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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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- Calpains play a role in insulin secretion and action.
Sreenan SK, Zhou YP, Otani K, Hansen PA, Currie KP, Pan CY, Lee JP, Ostrega DM, Pugh W, Horikawa Y, Cox NJ, Hanis CL, Burant CF, Fox AP, Bell GI, Polonsky KS
(2001) Diabetes 50: 2013-20 - Mechanisms of time-dependent potentiation of insulin release: involvement of nitric oxide synthase.
Gunawardana SC, Rocheleau JV, Head WS, Piston DW
(2006) Diabetes 55: 1029-33 - GSH is required to recycle ascorbic acid in cultured liver cell lines.
Li X, Qu ZC, May JM
(2001) Antioxid Redox Signal 3: 1089-97 - Pyridine Dinucleotides from Molecules to Man.
Fessel JP, Oldham WM
(2018) Antioxid Redox Signal 28: 180-212 - TRPM2 ion channels regulate macrophage polarization and gastric inflammation during Helicobacter pylori infection.
Beceiro S, Radin JN, Chatuvedi R, Piazuelo MB, Horvarth DJ, Cortado H, Gu Y, Dixon B, Gu C, Lange I, Koomoa DL, Wilson KT, Algood HM, Partida-Sánchez S
(2017) Mucosal Immunol 10: 493-507 - Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase.
Swart P, Swart AC, Waterman MR, Estabrook RW, Mason JI
(1993) J Clin Endocrinol Metab 77: 98-102 - No mutation in cytochrome P450 side chain cleavage in a patient with congenital lipoid adrenal hyperplasia.
Sakai Y, Yanase T, Okabe Y, Hara T, Waterman MR, Takayanagi R, Haji M, Nawata H
(1994) J Clin Endocrinol Metab 79: 1198-201 - Clinical, genetic, and enzymatic characterization of P450 oxidoreductase deficiency in four patients.
Sahakitrungruang T, Huang N, Tee MK, Agrawal V, Russell WE, Crock P, Murphy N, Migeon CJ, Miller WL
(2009) J Clin Endocrinol Metab 94: 4992-5000 - Microsomal cytochrome P450 and eicosanoid metabolism.
Capdevila JH, Harris RC, Falck JR
(2002) Cell Mol Life Sci 59: 780-9 - Polyamine- and NADPH-dependent generation of ROS during Helicobacter pylori infection: A blessing in disguise.
Gobert AP, Wilson KT
(2017) Free Radic Biol Med 105: 16-27 - Enzyme-dependent ascorbate recycling in human erythrocytes: role of thioredoxin reductase.
Mendiratta S, Qu ZC, May JM
(1998) Free Radic Biol Med 25: 221-8 - Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells.
Jones W, Li X, Qu ZC, Perriott L, Whitesell RR, May JM
(2002) Free Radic Biol Med 33: 83-93 - Developmentally regulated expression of adrenal 17 alpha-hydroxylase cytochrome P450 in the mouse embryo.
Keeney DS, Jenkins CM, Waterman MR
(1995) Endocrinology 136: 4872-9 - Pyruvate dehydrogenase complex and nicotinamide nucleotide transhydrogenase constitute an energy-consuming redox circuit.
Fisher-Wellman KH, Lin CT, Ryan TE, Reese LR, Gilliam LA, Cathey BL, Lark DS, Smith CD, Muoio DM, Neufer PD
(2015) Biochem J 467: 271-80 - The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3.
Capdevila JH, Wei S, Helvig C, Falck JR, Belosludtsev Y, Truan G, Graham-Lorence SE, Peterson JA
(1996) J Biol Chem 271: 22663-71 - Flavodoxin and NADPH-flavodoxin reductase from Escherichia coli support bovine cytochrome P450c17 hydroxylase activities.
Jenkins CM, Waterman MR
(1994) J Biol Chem 269: 27401-8 - Analysis of coumarin 7-hydroxylation activity of cytochrome P450 2A6 using random mutagenesis.
Kim D, Wu ZL, Guengerich FP
(2005) J Biol Chem 280: 40319-27 - Oxidation of N-Nitrosoalkylamines by human cytochrome P450 2A6: sequential oxidation to aldehydes and carboxylic acids and analysis of reaction steps.
Chowdhury G, Calcutt MW, Guengerich FP
(2010) J Biol Chem 285: 8031-44 - Pancreatic islet beta-cells transiently metabolize pyruvate.
Rocheleau JV, Head WS, Nicholson WE, Powers AC, Piston DW
(2002) J Biol Chem 277: 30914-20 - An active site substitution, F87V, converts cytochrome P450 BM-3 into a regio- and stereoselective (14S,15R)-arachidonic acid epoxygenase.
Graham-Lorence S, Truan G, Peterson JA, Falck JR, Wei S, Helvig C, Capdevila JH
(1997) J Biol Chem 272: 1127-35 - Coding nucleotide sequence of rat liver malic enzyme mRNA.
Magnuson MA, Morioka H, Tecce MF, Nikodem VM
(1986) J Biol Chem 261: 1183-6 - Quantitative subcellular imaging of glucose metabolism within intact pancreatic islets.
Bennett BD, Jetton TL, Ying G, Magnuson MA, Piston DW
(1996) J Biol Chem 271: 3647-51 - Reduction of dehydroascorbate to ascorbate by the selenoenzyme thioredoxin reductase.
May JM, Mendiratta S, Hill KE, Burk RF
(1997) J Biol Chem 272: 22607-10 - Reduction of the ascorbyl free radical to ascorbate by thioredoxin reductase.
May JM, Cobb CE, Mendiratta S, Hill KE, Burk RF
(1998) J Biol Chem 273: 23039-45 - Adenovirus-mediated knockout of a conditional glucokinase gene in isolated pancreatic islets reveals an essential role for proximal metabolic coupling events in glucose-stimulated insulin secretion.
Piston DW, Knobel SM, Postic C, Shelton KD, Magnuson MA
(1999) J Biol Chem 274: 1000-4 - Molecular cloning, expression, and enzymatic characterization of the rat kidney cytochrome P-450 arachidonic acid epoxygenase.
Karara A, Makita K, Jacobson HR, Falck JR, Guengerich FP, DuBois RN, Capdevila JH
(1993) J Biol Chem 268: 13565-70 - Oxidation of methoxyphenethylamines by cytochrome P450 2D6. Analysis of rate-limiting steps.
Guengerich FP, Miller GP, Hanna IH, Sato H, Martin MV
(2002) J Biol Chem 277: 33711-9 - Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines.
Wu L, Nicholson W, Knobel SM, Steffner RJ, May JM, Piston DW, Powers AC
(2004) J Biol Chem 279: 12126-34 - Quantitative NAD(P)H/flavoprotein autofluorescence imaging reveals metabolic mechanisms of pancreatic islet pyruvate response.
Rocheleau JV, Head WS, Piston DW
(2004) J Biol Chem 279: 31780-7 - Human erythrocyte recycling of ascorbic acid: relative contributions from the ascorbate free radical and dehydroascorbic acid.
May JM, Qu ZC, Cobb CE
(2004) J Biol Chem 279: 14975-82 - The identification and formation of 20-aldehyde leukotriene B4.
Soberman RJ, Sutyak JP, Okita RT, Wendelborn DF, Roberts LJ, Austen KF
(1988) J Biol Chem 263: 7996-8002 - Oxidation of halogenated compounds by cytochrome P-450, peroxidases, and model metalloporphyrins.
Guengerich FP
(1989) J Biol Chem 264: 17098-205 - Glucose suppression of glucagon secretion: metabolic and calcium responses from alpha-cells in intact mouse pancreatic islets.
Le Marchand SJ, Piston DW
(2010) J Biol Chem 285: 14389-98 - Cysteine 707 is involved in the dehydrogenase activity site of rat 10-formyltetrahydrofolate dehydrogenase.
Krupenko SA, Wagner C, Cook RJ
(1995) J Biol Chem 270: 519-22 - Purification and characterization of N-methylalanine dehydrogenase.
Lin MC, Wagner C
(1975) J Biol Chem 250: 3746-51 - Digitoxin metabolism by rat liver microsomes.
Schmoldt A, Benthe HF, Haberland G
(1975) Biochem Pharmacol 24: 1639-41 - Generation of oxidant stress in cultured endothelial cells by methylene blue: protective effects of glucose and ascorbic acid.
May JM, Qu ZC, Whitesell RR
(2003) Biochem Pharmacol 66: 777-84 - MTR and MTRR polymorphisms, dietary intake, and breast cancer risk.
Shrubsole MJ, Gao YT, Cai Q, Shu XO, Dai Q, Jin F, Zheng W
(2006) Cancer Epidemiol Biomarkers Prev 15: 586-8 - Glucose uptake and metabolism by cultured human skeletal muscle cells: rate-limiting steps.
Perriott LM, Kono T, Whitesell RR, Knobel SM, Piston DW, Granner DK, Powers AC, May JM
(2001) Am J Physiol Endocrinol Metab 281: E72-80
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