Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory. Morozov A, Muzzio IA, Bourtchouladze R, Van-Strien N, Lapidus K, Yin D, Winder DG, Adams JP, Sweatt JD, Kandel ER (2003) Neuron 39: 309-25 Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance. Münzel T, Sayegh H, Freeman BA, Tarpey MM, Harrison DG (1995) J Clin Invest 95: 187-94 Angiotensin II upregulates type-1 angiotensin II receptors in renal proximal tubule. Cheng HF, Becker BN, Burns KD, Harris RC (1995) J Clin Invest 95: 2012-9 Decreased adenylate cyclase activity and expression of Gs alpha in human myocardium after orthotopic cardiac transplantation. Loh E, Barnett JV, Feldman AM, Couper GS, Vatner DE, Colucci WS, Galper JB (1995) Circ Res 76: 852-60 Circadian gene expression in mammalian fibroblasts revealed by real-time luminescence reporting: temperature compensation and damping. Izumo M, Johnson CH, Yamazaki S (2003) Proc Natl Acad Sci U S A 100: 16089-94 Rapid endocytosis of the cystic fibrosis transmembrane conductance regulator chloride channel. Prince LS, Workman RB, Marchase RB (1994) Proc Natl Acad Sci U S A 91: 5192-6 GSK3beta mediates renal response to vasopressin by modulating adenylate cyclase activity. Rao R, Patel S, Hao C, Woodgett J, Harris R (2010) J Am Soc Nephrol 21: 428-37 Cocaine self-administration reduces excitatory responses in the mouse nucleus accumbens shell. Schramm-Sapyta NL, Olsen CM, Winder DG (2006) Neuropsychopharmacology 31: 1444-51 Protein kinase inhibitors selectively block phorbol ester- or forskolin-induced changes in excitability of Aplysia neurons. Conn PJ, Strong JA, Azhderian EM, Nairn AC, Greengard P, Kaczmarek LK (1989) J Neurosci 9: 473-9 Protein kinase C and A3 adenosine receptor activation inhibit presynaptic metabotropic glutamate receptor (mGluR) function and uncouple mGluRs from GTP-binding proteins. Macek TA, Schaffhauser H, Conn PJ (1998) J Neurosci 18: 6138-46 An essential role for modulation of hyperpolarization-activated current in the development of binaural temporal precision. Khurana S, Liu Z, Lewis AS, Rosa K, Chetkovich D, Golding NL (2012) J Neurosci 32: 2814-23 Proliferating human granulosa-lutein cells in long term monolayer culture: expression of aromatase, cholesterol side-chain cleavage, and 3 beta-hydroxysteroid dehydrogenase. McAllister JM, Mason JI, Byrd W, Trant JM, Waterman MR, Simpson ER (1990) J Clin Endocrinol Metab 71: 26-33 Beta 4 integrin expression in myelinating Schwann cells is polarized, developmentally regulated and axonally dependent. Feltri ML, Scherer SS, Nemni R, Kamholz J, Vogelbacker H, Scott MO, Canal N, Quaranta V, Wrabetz L (1994) Development 120: 1287-301 Dexamethasone inhibits corticotropin-induced accumulation of CYP11A and CYP17 messenger RNAs in bovine adrenocortical cells. Trzeciak WH, LeHoux JG, Waterman MR, Simpson ER (1993) Mol Endocrinol 7: 206-13 Interferon-stimulated gene ISG12b1 inhibits adipogenic differentiation and mitochondrial biogenesis in 3T3-L1 cells. Li B, Shin J, Lee K (2009) Endocrinology 150: 1217-24 Identification of the glucose transporter in mammalian cell membranes with a 125I-forskolin photoaffinity label. Wadzinski BE, Shanahan MF, Clark RB, Ruoho AE (1988) Biochem J 255: 983-90 Localization of the forskolin photolabelling site within the monosaccharide transporter of human erythrocytes. Wadzinski BE, Shanahan MF, Seamon KB, Ruoho AE (1990) Biochem J 272: 151-8 Antioxidant-induced nuclear translocation of CCAAT/enhancer-binding protein beta. A critical role for protein kinase A-mediated phosphorylation of Ser299. Chinery R, Brockman JA, Dransfield DT, Coffey RJ (1997) J Biol Chem 272: 30356-61 Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level. Hasty AH, Shimano H, Yahagi N, Amemiya-Kudo M, Perrey S, Yoshikawa T, Osuga J, Okazaki H, Tamura Y, Iizuka Y, Shionoiri F, Ohashi K, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N (2000) J Biol Chem 275: 31069-77 Protein kinase A-dependent transactivation by the E2A-Pbx1 fusion protein. Ogo A, Waterman MR, Kamps MP, Kagawa N (1995) J Biol Chem 270: 25340-3 Regulation of expression of the CYP11A (P450scc) gene in bovine ovarian luteal cells by forskolin and phorbol esters. Begeot M, Shetty U, Kilgore M, Waterman M, Simpson E (1993) J Biol Chem 268: 17317-25 Renin gene promoter activity in GC cells is regulated by cAMP and thyroid hormone through Pit-1-dependent mechanisms. Gilbert MT, Sun J, Yan Y, Oddoux C, Lazarus A, Tansey WP, Lavin TN, Catanzaro DF (1994) J Biol Chem 269: 28049-54 Distance-dependent interactions between basal, cyclic AMP, and thyroid hormone response elements in the rat growth hormone promoter. Tansey WP, Schaufele F, Heslewood M, Handford C, Reudelhuber TL, Catanzaro DF (1993) J Biol Chem 268: 14906-11 Targeting prostaglandin E2 receptors as an alternative strategy to block cyclooxygenase-2-dependent extracellular matrix-induced matrix metalloproteinase-9 expression by macrophages. Pavlovic S, Du B, Sakamoto K, Khan KM, Natarajan C, Breyer RM, Dannenberg AJ, Falcone DJ (2006) J Biol Chem 281: 3321-8 Regulation of CYP11A (P450SCC) and CYP17 (P450(17) alpha) gene expression in bovine luteal cells in primary culture. Lauber ME, Bengtson T, Waterman MR, Simpson ER (1991) J Biol Chem 266: 11170-5 Evidence that an adrenal-specific nuclear protein regulates the cAMP responsiveness of the human CYP21B (P450C21) gene. Kagawa N, Waterman MR (1991) J Biol Chem 266: 11199-204 cAMP-dependent transcription of the human CYP21B (P-450C21) gene requires a cis-regulatory element distinct from the consensus cAMP-regulatory element. Kagawa N, Waterman MR (1990) J Biol Chem 265: 11299-305 Characterization of the promoter/regulatory region of the bovine CYP11A (P-450scc) gene. Basal and cAMP-dependent expression. Ahlgren R, Simpson ER, Waterman MR, Lund J (1990) J Biol Chem 265: 3313-9 Phosphorylation of the inositol 1,4,5-trisphosphate receptor. Cyclic GMP-dependent protein kinase mediates cAMP and cGMP dependent phosphorylation in the intact rat aorta. Komalavilas P, Lincoln TM (1996) J Biol Chem 271: 21933-8 Derivatization of the human erythrocyte glucose transporter using a novel forskolin photoaffinity label. Wadzinski BE, Shanahan MF, Ruoho AE (1987) J Biol Chem 262: 17683-9 Axonal neuregulin 1 type III activates NF-kappaB in Schwann cells during myelin formation. Limpert AS, Carter BD (2010) J Biol Chem 285: 16614-22 Time-dependent biphasic regulation of Na+/K+/Cl- cotransport in rat glomerular mesangial cells. Homma T, Harris RC (1991) J Biol Chem 266: 13553-9 AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus. Larocca MC, Shanks RA, Tian L, Nelson DL, Stewart DM, Goldenring JR (2004) Mol Biol Cell 15: 2771-81 Cross-talk between G(s)- and G(q)-coupled pathways in regulation of interleukin-4 by A(2B) adenosine receptors in human mast cells. Ryzhov S, Goldstein AE, Biaggioni I, Feoktistov I (2006) Mol Pharmacol 70: 727-35 Androgen receptor activity at the prostate specific antigen locus: steroidal and non-steroidal mechanisms. Jia L, Kim J, Shen H, Clark PE, Tilley WD, Coetzee GA (2003) Mol Cancer Res 1: 385-92 Regulation of CYP11A gene expression in bovine ovarian granulosa cells in primary culture by cAMP and phorbol esters is conferred by a common cis-acting element. Lauber ME, Picton HM, Begeot M, Momoi K, Waterman MR, Simpson ER (1993) Mol Cell Endocrinol 94: 235-42 cAMP-dependent and tissue-specific expression of genes encoding steroidogenic enzymes in bovine luteal and granulosa cells in primary culture. Lauber ME, Kagawa N, Waterman MR, Simpson ER (1993) Mol Cell Endocrinol 93: 227-33 Cyclic AMP-dependent protein kinase phosphorylates group III metabotropic glutamate receptors and inhibits their function as presynaptic receptors. Cai Z, Saugstad JA, Sorensen SD, Ciombor KJ, Zhang C, Schaffhauser H, Hubalek F, Pohl J, Duvoisin RM, Conn PJ (2001) J Neurochem 78: 756-66 nMDA receptor activation increases cyclic AMP in area CA1 of the hippocampus via calcium/calmodulin stimulation of adenylyl cyclase. Chetkovich DM, Sweatt JD (1993) J Neurochem 61: 1933-42 Analysis of the proenkephalin second messenger-inducible enhancer in rat striatal cultures. Konradi C, Cole RL, Green D, Senatus P, Leveque JC, Pollack AE, Grossbard SJ, Hyman SE (1995) J Neurochem 65: 1007-15
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.