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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Retroviridae are shown below. Double-click or tap a node for more information.
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- Immunology: TRIM5 does double duty.
Aiken C, Joyce S
(2011) Nature 472: 305-6 - Inhibition of NF-kappaB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis.
Bushdid PB, Brantley DM, Yull FE, Blaeuer GL, Hoffman LH, Niswander L, Kerr LD
(1998) Nature 392: 615-8 - Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development.
Golling G, Amsterdam A, Sun Z, Antonelli M, Maldonado E, Chen W, Burgess S, Haldi M, Artzt K, Farrington S, Lin SY, Nissen RM, Hopkins N
(2002) Nat Genet 31: 135-40 - Protein kinase C phosphorylates pp60src at a novel site.
Gould KL, Woodgett JR, Cooper JA, Buss JE, Shalloway D, Hunter T
(1985) Cell 42: 849-57 - Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1.
Sorrentino BP, Brandt SJ, Bodine D, Gottesman M, Pastan I, Cline A, Nienhuis AW
(1992) Science 257: 99-103 - Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart.
Brown CB, Boyer AS, Runyan RB, Barnett JV
(1999) Science 283: 2080-2 - Gene therapy insertional mutagenesis insights.
Davé UP, Jenkins NA, Copeland NG
(2004) Science 303: 333 - Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer.
Roth JA, Nguyen D, Lawrence DD, Kemp BL, Carrasco CH, Ferson DZ, Hong WK, Komaki R, Lee JJ, Nesbitt JC, Pisters KM, Putnam JB, Schea R, Shin DM, Walsh GL, Dolormente MM, Han CI, Martin FD, Yen N, Xu K, Stephens LC, McDonnell TJ, Mukhopadhyay T, Cai D
(1996) Nat Med 2: 985-91 - Isoform-specific effects of apolipoprotein E on atherogenesis: gene transduction studies in mice.
Yoshida H, Hasty AH, Major AS, Ishiguro H, Su YR, Gleaves LA, Babaev VR, Linton MF, Fazio S
(2001) Circulation 104: 2820-5 - Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation.
Hasty AH, Linton MF, Brandt SJ, Babaev VR, Gleaves LA, Fazio S
(1999) Circulation 99: 2571-6 - Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.
Brandt SJ, Bodine DM, Dunbar CE, Nienhuis AW
(1990) J Clin Invest 86: 592-9 - Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.
Biswas S, Guix M, Rinehart C, Dugger TC, Chytil A, Moses HL, Freeman ML, Arteaga CL
(2007) J Clin Invest 117: 1305-13 - Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies.
Packham G, White EL, Eischen CM, Yang H, Parganas E, Ihle JN, Grillot DA, Zambetti GP, Nuñez G, Cleveland JL
(1998) Genes Dev 12: 2475-87 - Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus.
Reynolds AB, Vila J, Lansing TJ, Potts WM, Weber MJ, Parsons JT
(1987) EMBO J 6: 2359-64 - Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis.
Keller UB, Old JB, Dorsey FC, Nilsson JA, Nilsson L, MacLean KH, Chung L, Yang C, Spruck C, Boyd K, Reed SI, Cleveland JL
(2007) EMBO J 26: 2562-74 - Isolation of cellular promoters by using a retrovirus promoter trap.
von Melchner H, Reddy S, Ruley HE
(1990) Proc Natl Acad Sci U S A 87: 3733-7 - Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.
Bodine DM, McDonagh KT, Brandt SJ, Ney PA, Agricola B, Byrne E, Nienhuis AW
(1990) Proc Natl Acad Sci U S A 87: 3738-42 - Tissue-targeted antisense c-fos retroviral vector inhibits established breast cancer xenografts in nude mice.
Arteaga CL, Holt JT
(1996) Cancer Res 56: 1098-1103 - Deletion of the COOH-terminal domain of CXC chemokine receptor 4 leads to the down-regulation of cell-to-cell contact, enhanced motility and proliferation in breast carcinoma cells.
Ueda Y, Neel NF, Schutyser E, Raman D, Richmond A
(2006) Cancer Res 66: 5665-75 - Retroviruses as genetic tools to isolate transcriptionally active chromosomal regions.
von Melchner H, Ruley HE
(1990) Environ Health Perspect 88: 141-8 - Identification of a novel cardiac-specific transcript critical for cardiac myocyte differentiation.
Wei Y, Bader D, Litvin J
(1996) Development 122: 2779-89 - Radiosensitivity of small-cell lung cancer xenografts compared with activity of c-myc, N-myc, L-myc, c-raf-1 and K-ras proto-oncogenes.
Rygaard K, Slebos RJ, Spang-Thomsen M
(1991) Int J Cancer 49: 279-84 - EGFR signaling to p120-catenin through phosphorylation at Y228.
Mariner DJ, Davis MA, Reynolds AB
(2004) J Cell Sci 117: 1339-50 - Immune Regulation in Eutherian Pregnancy: Live Birth Coevolved with Novel Immune Genes and Gene Regulation.
Moon JM, Capra JA, Abbot P, Rokas A
(2019) Bioessays 41: e1900072 - deltaNp73 facilitates cell immortalization and cooperates with oncogenic Ras in cellular transformation in vivo.
Petrenko O, Zaika A, Moll UM
(2003) Mol Cell Biol 23: 5540-55 - Identification of rCop-1, a new member of the CCN protein family, as a negative regulator for cell transformation.
Zhang R, Averboukh L, Zhu W, Zhang H, Jo H, Dempsey PJ, Coffey RJ, Pardee AB, Liang P
(1998) Mol Cell Biol 18: 6131-41 - Stable association of activated pp60src with two tyrosine-phosphorylated cellular proteins.
Reynolds AB, Kanner SB, Wang HC, Parsons JT
(1989) Mol Cell Biol 9: 3951-8 - High-throughput selection of retrovirus producer cell lines leads to markedly improved efficiency of germ line-transmissible insertions in zebra fish.
Chen W, Burgess S, Golling G, Amsterdam A, Hopkins N
(2002) J Virol 76: 2192-8 - Identification of cellular promoters by using a retrovirus promoter trap.
von Melchner H, Ruley HE
(1989) J Virol 63: 3227-33 - Cell surface expression and orientation in membranes of the 44-amino-acid SH protein of simian virus 5.
Hiebert SW, Richardson CD, Lamb RA
(1988) J Virol 62: 2347-57 - Retroviral-mediated transfer of interleukin-6 into hematopoietic cells of mice results in a syndrome resembling Castleman's disease.
Brandt SJ, Bodine DM, Dunbar CE, Nienhuis AW
(1990) Curr Top Microbiol Immunol 166: 37-41 - Prostaglandin A2 blocks the activation of G1 phase cyclin-dependent kinase without altering mitogen-activated protein kinase stimulation.
Hitomi M, Shu J, Strom D, Hiebert SW, Harter ML, Stacey DW
(1996) J Biol Chem 271: 9376-83 - SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells.
Huang IC, Bosch BJ, Li F, Li W, Lee KH, Ghiran S, Vasilieva N, Dermody TS, Harrison SC, Dormitzer PR, Farzan M, Rottier PJ, Choe H
(2006) J Biol Chem 281: 3198-203 - Differential roles of C-terminal activation motifs in the establishment of Stat6 transcriptional specificity.
Goenka S, Marlar C, Schindler U, Boothby M
(2003) J Biol Chem 278: 50362-70 - Overexpression of HER2 (erbB2) in human breast epithelial cells unmasks transforming growth factor beta-induced cell motility.
Ueda Y, Wang S, Dumont N, Yi JY, Koh Y, Arteaga CL
(2004) J Biol Chem 279: 24505-13 - Integrin alpha6beta4-erbB2 complex inhibits haptotaxis by up-regulating E-cadherin cell-cell junctions in keratinocytes.
Hintermann E, Yang N, O'Sullivan D, Higgins JM, Quaranta V
(2005) J Biol Chem 280: 8004-15 - Retrovirus-mediated expression of apolipoprotein A-I in the macrophage protects against atherosclerosis in vivo.
Ishiguro H, Yoshida H, Major AS, Zhu T, Babaev VR, Linton MF, Fazio S
(2001) J Biol Chem 276: 36742-8 - Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes.
Breyer JP, McReynolds KM, Yaspan BL, Bradley KM, Dupont WD, Smith JR
(2009) Cancer Epidemiol Biomarkers Prev 18: 2137-44 - Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells.
Brábek J, Constancio SS, Siesser PF, Shin NY, Pozzi A, Hanks SK
(2005) Mol Cancer Res 3: 307-15 - Rapid extravasation and establishment of breast cancer micrometastases in the liver microenvironment.
Martin MD, Kremers GJ, Short KW, Rocheleau JV, Xu L, Piston DW, Matrisian LM, Gorden DL
(2010) Mol Cancer Res 8: 1319-27
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