Keyword Connections

•  David Cortez
•  James Goldenring
•  Kathleen Gould

•  Laura Lee
•  Sandra Zinkel
•  Scott Hiebert

•  Stephen Hann

Resources

• No matching connections

Communities

• Goldenring Lab
• Hiebert Lab
• Zinkel Lab

Publications

• Conducting the mitotic symphony.
  Cortez D, Elledge SJ
  (2000) Nature 406: 354-6
• Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis.
  Gould KL, Nurse P
  (1989) Nature 342: 39-45
• Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants.
  Hemann MT, Bric A, Teruya-Feldstein J, Herbst A, Nilsson JA, Cordon-Cardo C, Cleveland JL, Tansey WP, Lowe SW
  (2005) Nature 436: 807-11
• NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein.
  Tooley CE, Petkowski JJ, Muratore-Schroeder TL, Balsbaugh JL, Shabanowitz J, Sabat M, Minor W, Hunt DF, Macara IG
  (2010) Nature 466: 1125-8
• Comprehensive molecular profiling of lung adenocarcinoma.
  Cancer Genome Atlas Research Network
  (2014) Nature 511: 543-50
• p19ARF directly and differentially controls the functions of c-Myc independently of p53.
  Qi Y, Gregory MA, Li Z, Brousal JP, West K, Hann SR
  (2004) Nature 431: 712-7
• ATR: an essential regulator of genome integrity.
  Cimprich KA, Cortez D
  (2008) Nat Rev Mol Cell Biol 9: 616-27
• Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.
  Dunning AM, Michailidou K, Kuchenbaecker KB, Thompson D, French JD, Beesley J, Healey CS, Kar S, Pooley KA, Lopez-Knowles E, Dicks E, Barrowdale D, Sinnott-Armstrong NA, Sallari RC, Hillman KM, Kaufmann S, Sivakumaran H, Moradi Marjaneh M, Lee JS, Hills M, Jarosz M, Drury S, Canisius S, Bolla MK, Dennis J, Wang Q, Hopper JL, Southey MC, Broeks A, Schmidt MK, Lophatananon A, Muir K, Beckmann MW, Fasching PA, Dos-Santos-Silva I, Peto J, Sawyer EJ, Tomlinson I, Burwinkel B, Marme F, Guénel P, Truong T, Bojesen SE, Flyger H, González-Neira A, Perez JI, Anton-Culver H, Eunjung L, Arndt V, Brenner H, Meindl A, Schmutzler RK, Brauch H, Hamann U, Aittomäki K, Blomqvist C, Ito H, Matsuo K, Bogdanova N, Dörk T, Lindblom A, Margolin S, Kosma VM, Mannermaa A, Tseng CC, Wu AH, Lambrechts D, Wildiers H, Chang-Claude J, Rudolph A, Peterlongo P, Radice P, Olson JE, Giles GG, Milne RL, Haiman CA, Henderson BE, Goldberg MS, Teo SH, Yip CH, Nord S, Borresen-Dale AL, Kristensen V, Long J, Zheng W, Pylkäs K, Winqvist R, Andrulis IL, Knight JA, Devilee P, Seynaeve C, Figueroa J, Sherman ME, Czene K, Darabi H, Hollestelle A, van den Ouweland AM, Humphreys K, Gao YT, Shu XO, Cox A, Cross SS, Blot W, Cai Q, Ghoussaini M, Perkins BJ, Shah M, Choi JY, Kang D, Lee SC, Hartman M, Kabisch M, Torres D, Jakubowska A, Lubinski J, Brennan P, Sangrajrang S, Ambrosone CB, Toland AE, Shen CY, Wu PE, Orr N, Swerdlow A, McGuffog L, Healey S, Lee A, Kapuscinski M, John EM, Terry MB, Daly MB, Goldgar DE, Buys SS, Janavicius R, Tihomirova L, Tung N, Dorfling CM, van Rensburg EJ, Neuhausen SL, Ejlertsen B, Hansen TV, Osorio A, Benitez J, Rando R, Weitzel JN, Bonanni B, Peissel B, Manoukian S, Papi L, Ottini L, Konstantopoulou I, Apostolou P, Garber J, Rashid MU, Frost D, EMBRACE, Izatt L, Ellis S, Godwin AK, Arnold N, Niederacher D, Rhiem K, Bogdanova-Markov N, Sagne C, Stoppa-Lyonnet D, Damiola F, GEMO Study Collaborators, Sinilnikova OM, Mazoyer S, Isaacs C, Claes KB, De Leeneer K, de la Hoya M, Caldes T, Nevanlinna H, Khan S, Mensenkamp AR, HEBON, Hooning MJ, Rookus MA, Kwong A, Olah E, Diez O, Brunet J, Pujana MA, Gronwald J, Huzarski T, Barkardottir RB, Laframboise R, Soucy P, Montagna M, Agata S, Teixeira MR, kConFab Investigators, Park SK, Lindor N, Couch FJ, Tischkowitz M, Foretova L, Vijai J, Offit K, Singer CF, Rappaport C, Phelan CM, Greene MH, Mai PL, Rennert G, Imyanitov EN, Hulick PJ, Phillips KA, Piedmonte M, Mulligan AM, Glendon G, Bojesen A, Thomassen M, Caligo MA, Yoon SY, Friedman E, Laitman Y, Borg A, von Wachenfeldt A, Ehrencrona H, Rantala J, Olopade OI, Ganz PA, Nussbaum RL, Gayther SA, Nathanson KL, Domchek SM, Arun BK, Mitchell G, Karlan BY, Lester J, Maskarinec G, Woolcott C, Scott C, Stone J, Apicella C, Tamimi R, Luben R, Khaw KT, Helland Å, Haakensen V, Dowsett M, Pharoah PD, Simard J, Hall P, García-Closas M, Vachon C, Chenevix-Trench G, Antoniou AC, Easton DF, Edwards SL
  (2016) Nat Genet 48: 374-86
• Abnormal TNF activity in Timp3-/- mice leads to chronic hepatic inflammation and failure of liver regeneration.
  Mohammed FF, Smookler DS, Taylor SE, Fingleton B, Kassiri Z, Sanchez OH, English JL, Matrisian LM, Au B, Yeh WC, Khokha R
  (2004) Nat Genet 36: 969-77
• p53-dependent apoptosis modulates the cytotoxicity of anticancer agents.
  Lowe SW, Ruley HE, Jacks T, Housman DE
  (1993) Cell 74: 957-67
• The E2F transcription factor is a cellular target for the RB protein.
  Chellappan SP, Hiebert S, Mudryj M, Horowitz JM, Nevins JR
  (1991) Cell 65: 1053-61
• Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion.
  Crawley SW, Shifrin DA, Grega-Larson NE, McConnell RE, Benesh AE, Mao S, Zheng Y, Zheng QY, Nam KT, Millis BA, Kachar B, Tyska MJ
  (2014) Cell 157: 433-446
• Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A.
  Mudryj M, Devoto SH, Hiebert SW, Hunter T, Pines J, Nevins JR
  (1991) Cell 65: 1243-53
• Bid plays a role in the DNA damage response.
  Zinkel SS, Hurov KE, Gross A
  (2007) Cell 130: 9-10; author reply 10-1
• A role for proapoptotic BID in the DNA-damage response.
  Zinkel SS, Hurov KE, Ong C, Abtahi FM, Gross A, Korsmeyer SJ
  (2005) Cell 122: 579-91
• Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks.
  Cortez D, Wang Y, Qin J, Elledge SJ
  (1999) Science 286: 1162-6
• ATR and ATRIP: partners in checkpoint signaling.
  Cortez D, Guntuku S, Qin J, Elledge SJ
  (2001) Science 294: 1713-6
• Complementation of the mitotic activator, p80cdc25, by a human protein-tyrosine phosphatase.
  Gould KL, Moreno S, Tonks NK, Nurse P
  (1990) Science 250: 1573-6
• Neuroscience. Synapses here and not everywhere.
  Miller DM
  (2007) Science 317: 907-8
• Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.
  Zhang B, Beeghly-Fadiel A, Long J, Zheng W
  (2011) Lancet Oncol 12: 477-88
• Crashing waves of destruction: the cell cycle and APC(Cdh1) regulation of SCF(Skp2).
  Kurland JF, Tansey WP
  (2004) Cancer Cell 5: 305-6
• Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis.
  McCaffrey LM, Montalbano J, Mihai C, Macara IG
  (2012) Cancer Cell 22: 601-14
• HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma.
  Gordan JD, Lal P, Dondeti VR, Letrero R, Parekh KN, Oquendo CE, Greenberg RA, Flaherty KT, Rathmell WK, Keith B, Simon MC, Nathanson KL
  (2008) Cancer Cell 14: 435-46
• lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.
  Wang Z, Yang B, Zhang M, Guo W, Wu Z, Wang Y, Jia L, Li S, Cancer Genome Atlas Research Network, Xie W, Yang D
  (2018) Cancer Cell 33: 706-720.e9
• Genomic and Functional Approaches to Understanding Cancer Aneuploidy.
  Taylor AM, Shih J, Ha G, Gao GF, Zhang X, Berger AC, Schumacher SE, Wang C, Hu H, Liu J, Lazar AJ, Cancer Genome Atlas Research Network, Cherniack AD, Beroukhim R, Meyerson M
  (2018) Cancer Cell 33: 676-689.e3
• LZAP, a putative tumor suppressor, selectively inhibits NF-kappaB.
  Wang J, An H, Mayo MW, Baldwin AS, Yarbrough WG
  (2007) Cancer Cell 12: 239-51
• The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma.
  Rosenwald A, Wright G, Wiestner A, Chan WC, Connors JM, Campo E, Gascoyne RD, Grogan TM, Muller-Hermelink HK, Smeland EB, Chiorazzi M, Giltnane JM, Hurt EM, Zhao H, Averett L, Henrickson S, Yang L, Powell J, Wilson WH, Jaffe ES, Simon R, Klausner RD, Montserrat E, Bosch F, Greiner TC, Weisenburger DD, Sanger WG, Dave BJ, Lynch JC, Vose J, Armitage JO, Fisher RI, Miller TP, LeBlanc M, Ott G, Kvaloy S, Holte H, Delabie J, Staudt LM
  (2003) Cancer Cell 3: 185-97
• p53 and MDM2: antagonists or partners in crime?
  Eischen CM, Lozano G
  (2009) Cancer Cell 15: 161-2
• PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.
  Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL
  (2002) Nat Med 8: 1145-52
• Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury.
  Yang L, Besschetnova TY, Brooks CR, Shah JV, Bonventre JV
  (2010) Nat Med 16: 535-43, 1p following 143
• The Par3-like polarity protein Par3L is essential for mammary stem cell maintenance.
  Huo Y, Macara IG
  (2014) Nat Cell Biol 16: 529-37
• ETAA1 acts at stalled replication forks to maintain genome integrity.
  Bass TE, Luzwick JW, Kavanaugh G, Carroll C, Dungrawala H, Glick GG, Feldkamp MD, Putney R, Chazin WJ, Cortez D
  (2016) Nat Cell Biol 18: 1185-1195
• Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma.
  Trunzer K, Pavlick AC, Schuchter L, Gonzalez R, McArthur GA, Hutson TE, Moschos SJ, Flaherty KT, Kim KB, Weber JS, Hersey P, Long GV, Lawrence D, Ott PA, Amaravadi RK, Lewis KD, Puzanov I, Lo RS, Koehler A, Kockx M, Spleiss O, Schell-Steven A, Gilbert HN, Cockey L, Bollag G, Lee RJ, Joe AK, Sosman JA, Ribas A
  (2013) J Clin Oncol 31: 1767-74
• Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues.
  Lee LA, Orr-Weaver TL
  (2003) Annu Rev Genet 37: 545-78
• The Replication Checkpoint Prevents Two Types of Fork Collapse without Regulating Replisome Stability.
  Dungrawala H, Rose KL, Bhat KP, Mohni KN, Glick GG, Couch FB, Cortez D
  (2015) Mol Cell 59: 998-1010
• Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site.
  Roberts-Galbraith RH, Ohi MD, Ballif BA, Chen JS, McLeod I, McDonald WH, Gygi SP, Yates JR, Gould KL
  (2010) Mol Cell 39: 86-99
• SOSS1/2: Sensors of single-stranded DNA at a break.
  Nam EA, Cortez D
  (2009) Mol Cell 35: 258-9