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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Proto-Oncogene Proteins c-myc are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Proto-Oncogene Proteins c-myc.
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Publications
- p19ARF directly and differentially controls the functions of c-Myc independently of p53.
Qi Y, Gregory MA, Li Z, Brousal JP, West K, Hann SR
(2004) Nature 431: 712-7 - Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants.
Hemann MT, Bric A, Teruya-Feldstein J, Herbst A, Nilsson JA, Cordon-Cardo C, Cleveland JL, Tansey WP, Lowe SW
(2005) Nature 436: 807-11 - A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas.
Hann SR, King MW, Bentley DL, Anderson CW, Eisenman RN
(1988) Cell 52: 185-95 - TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains.
Pietenpol JA, Stein RW, Moran E, Yaciuk P, Schlegel R, Lyons RM, Pittelkow MR, Münger K, Howley PM, Moses HL
(1990) Cell 61: 777-85 - A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins.
Murre C, McCaw PS, Baltimore D
(1989) Cell 56: 777-83 - Systemic elevation of PTEN induces a tumor-suppressive metabolic state.
Garcia-Cao I, Song MS, Hobbs RM, Laurent G, Giorgi C, de Boer VC, Anastasiou D, Ito K, Sasaki AT, Rameh L, Carracedo A, Vander Heiden MG, Cantley LC, Pinton P, Haigis MC, Pandolfi PP
(2012) Cell 149: 49-62 - HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma.
Gordan JD, Lal P, Dondeti VR, Letrero R, Parekh KN, Oquendo CE, Greenberg RA, Flaherty KT, Rathmell WK, Keith B, Simon MC, Nathanson KL
(2008) Cancer Cell 14: 435-46 - Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics.
Sarosiek KA, Fraser C, Muthalagu N, Bhola PD, Chang W, McBrayer SK, Cantlon A, Fisch S, Golomb-Mello G, Ryan JA, Deng J, Jian B, Corbett C, Goldenberg M, Madsen JR, Liao R, Walsh D, Sedivy J, Murphy DJ, Carrasco DR, Robinson S, Moslehi J, Letai A
(2017) Cancer Cell 31: 142-156 - lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.
Wang Z, Yang B, Zhang M, Guo W, Wu Z, Wang Y, Jia L, Li S, Cancer Genome Atlas Research Network, Xie W, Yang D
(2018) Cancer Cell 33: 706-720.e9 - Cytogenetic prognostication within medulloblastoma subgroups.
Shih DJ, Northcott PA, Remke M, Korshunov A, Ramaswamy V, Kool M, Luu B, Yao Y, Wang X, Dubuc AM, Garzia L, Peacock J, Mack SC, Wu X, Rolider A, Morrissy AS, Cavalli FM, Jones DT, Zitterbart K, Faria CC, Schüller U, Kren L, Kumabe T, Tominaga T, Shin Ra Y, Garami M, Hauser P, Chan JA, Robinson S, Bognár L, Klekner A, Saad AG, Liau LM, Albrecht S, Fontebasso A, Cinalli G, De Antonellis P, Zollo M, Cooper MK, Thompson RC, Bailey S, Lindsey JC, Di Rocco C, Massimi L, Michiels EM, Scherer SW, Phillips JJ, Gupta N, Fan X, Muraszko KM, Vibhakar R, Eberhart CG, Fouladi M, Lach B, Jung S, Wechsler-Reya RJ, Fèvre-Montange M, Jouvet A, Jabado N, Pollack IF, Weiss WA, Lee JY, Cho BK, Kim SK, Wang KC, Leonard JR, Rubin JB, de Torres C, Lavarino C, Mora J, Cho YJ, Tabori U, Olson JM, Gajjar A, Packer RJ, Rutkowski S, Pomeroy SL, French PJ, Kloosterhof NK, Kros JM, Van Meir EG, Clifford SC, Bourdeaut F, Delattre O, Doz FF, Hawkins CE, Malkin D, Grajkowska WA, Perek-Polnik M, Bouffet E, Rutka JT, Pfister SM, Taylor MD
(2014) J Clin Oncol 32: 886-96 - Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC.
Thomas LR, Wang Q, Grieb BC, Phan J, Foshage AM, Sun Q, Olejniczak ET, Clark T, Dey S, Lorey S, Alicie B, Howard GC, Cawthon B, Ess KC, Eischen CM, Zhao Z, Fesik SW, Tansey WP
(2015) Mol Cell 58: 440-52 - Skp2 regulates Myc protein stability and activity.
Kim SY, Herbst A, Tworkowski KA, Salghetti SE, Tansey WP
(2003) Mol Cell 11: 1177-88 - MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation.
Lee KM, Giltnane JM, Balko JM, Schwarz LJ, Guerrero-Zotano AL, Hutchinson KE, Nixon MJ, Estrada MV, Sánchez V, Sanders ME, Lee T, Gómez H, Lluch A, Pérez-Fidalgo JA, Wolf MM, Andrejeva G, Rathmell JC, Fesik SW, Arteaga CL
(2017) Cell Metab 26: 633-647.e7 - Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.
Anderson PD, McKissic SA, Logan M, Roh M, Franco OE, Wang J, Doubinskaia I, van der Meer R, Hayward SW, Eischen CM, Eltoum IE, Abdulkadir SA
(2012) J Clin Invest 122: 1907-19 - Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis.
Xiao Q, Claassen G, Shi J, Adachi S, Sedivy J, Hann SR
(1998) Genes Dev 12: 3803-8 - A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice.
Davis AC, Wims M, Spotts GD, Hann SR, Bradley A
(1993) Genes Dev 7: 671-82 - Translational activation of the non-AUG-initiated c-myc 1 protein at high cell densities due to methionine deprivation.
Hann SR, Sloan-Brown K, Spotts GD
(1992) Genes Dev 6: 1229-40 - The alternatively initiated c-Myc proteins differentially regulate transcription through a noncanonical DNA-binding site.
Hann SR, Dixit M, Sears RC, Sealy L
(1994) Genes Dev 8: 2441-52 - c-Myc downregulation is required for preacinar to acinar maturation and pancreatic homeostasis.
Sánchez-Arévalo Lobo VJ, Fernández LC, Carrillo-de-Santa-Pau E, Richart L, Cobo I, Cendrowski J, Moreno U, Del Pozo N, Megías D, Bréant B, Wright CV, Magnuson M, Real FX
(2018) Gut 67: 707-718 - BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesis.
Parang B, Kaz AM, Barrett CW, Short SP, Ning W, Keating CE, Mittal MK, Naik RD, Washington MK, Revetta FL, Smith JJ, Chen X, Wilson KT, Brand T, Bader DM, Tansey WP, Chen R, Brentnall TA, Grady WM, Williams CS
(2017) Gut 66: 852-862 - A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells.
Moad M, Pal D, Hepburn AC, Williamson SC, Wilson L, Lako M, Armstrong L, Hayward SW, Franco OE, Cates JM, Fordham SE, Przyborski S, Carr-Wilkinson J, Robson CN, Heer R
(2013) Eur Urol 64: 753-61 - Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis.
Keller UB, Old JB, Dorsey FC, Nilsson JA, Nilsson L, MacLean KH, Chung L, Yang C, Spruck C, Boyd K, Reed SI, Cleveland JL
(2007) EMBO J 26: 2562-74 - Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.
Salghetti SE, Kim SY, Tansey WP
(1999) EMBO J 18: 717-26 - MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme.
Suh SS, Yoo JY, Nuovo GJ, Jeon YJ, Kim S, Lee TJ, Kim T, Bakàcs A, Alder H, Kaur B, Aqeilan RI, Pichiorri F, Croce CM
(2012) Proc Natl Acad Sci U S A 109: 5316-21 - Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.
Alexandrow MG, Kawabata M, Aakre M, Moses HL
(1995) Proc Natl Acad Sci U S A 92: 3239-43 - E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor.
Hiebert SW, Lipp M, Nevins JR
(1989) Proc Natl Acad Sci U S A 86: 3594-8 - Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation.
Pietenpol JA, Holt JT, Stein RW, Moses HL
(1990) Proc Natl Acad Sci U S A 87: 3758-62 - Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism.
Boone DN, Qi Y, Li Z, Hann SR
(2011) Proc Natl Acad Sci U S A 108: 632-7 - A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest.
Claassen GF, Hann SR
(2000) Proc Natl Acad Sci U S A 97: 9498-503 - Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation.
Li Z, Boone D, Hann SR
(2008) Proc Natl Acad Sci U S A 105: 18794-9 - Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc.
Tworkowski KA, Chakraborty AA, Samuelson AV, Seger YR, Narita M, Hannon GJ, Lowe SW, Tansey WP
(2008) Proc Natl Acad Sci U S A 105: 6103-8 - Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity.
Zhang Q, Spears E, Boone DN, Li Z, Gregory MA, Hann SR
(2013) Proc Natl Acad Sci U S A 110: 978-83 - Epithelial cell organization suppresses Myc function by attenuating Myc expression.
Simpson DR, Yu M, Zheng S, Zhao Z, Muthuswamy SK, Tansey WP
(2011) Cancer Res 71: 3822-30 - Myc Induces miRNA-Mediated Apoptosis in Response to HDAC Inhibition in Hematologic Malignancies.
Adams CM, Hiebert SW, Eischen CM
(2016) Cancer Res 76: 736-48 - The MYC-WDR5 Nexus and Cancer.
Thomas LR, Foshage AM, Weissmiller AM, Tansey WP
(2015) Cancer Res 75: 4012-5 - Myc-mediated transcriptional repression by recruitment of histone deacetylase.
Kurland JF, Tansey WP
(2008) Cancer Res 68: 3624-9 - Adenoviral E1A function through Myc.
Chakraborty AA, Tansey WP
(2009) Cancer Res 69: 6-9 - c-myc overexpression causes anaplasia in medulloblastoma.
Stearns D, Chaudhry A, Abel TW, Burger PC, Dang CV, Eberhart CG
(2006) Cancer Res 66: 673-81 - Oncogenic protein MTBP interacts with MYC to promote tumorigenesis.
Grieb BC, Gramling MW, Arrate MP, Chen X, Beauparlant SL, Haines DS, Xiao H, Eischen CM
(2014) Cancer Res 74: 3591-602 - Id2 is dispensable for myc-induced lymphomagenesis.
Nilsson JA, Nilsson LM, Keller U, Yokota Y, Boyd K, Cleveland JL
(2004) Cancer Res 64: 7296-301
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