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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Publications
- The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Bernard GR, Wheeler AP, Russell JA, Schein R, Summer WR, Steinberg KP, Fulkerson WJ, Wright PE, Christman BW, Dupont WD, Higgins SB, Swindell BB
(1997) N Engl J Med 336: 912-8 - Mechanisms and management of retinopathy of prematurity.
Hartnett ME, Penn JS
(2012) N Engl J Med 367: 2515-26 - Anthracyclines and heart failure.
Sawyer DB
(2013) N Engl J Med 368: 1154-6 - High-dose corticosteroids in patients with the adult respiratory distress syndrome.
Bernard GR, Luce JM, Sprung CL, Rinaldo JE, Tate RM, Sibbald WJ, Kariman K, Higgins S, Bradley R, Metz CA
(1987) N Engl J Med 317: 1565-70 - Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: cross-talk between the eicosanoid and endocannabinoid signaling pathways.
Rouzer CA, Marnett LJ
(2011) Chem Rev 111: 5899-921 - Isoprostane generation and function.
Milne GL, Yin H, Hardy KD, Davies SS, Roberts LJ
(2011) Chem Rev 111: 5973-96 - Telomere dysfunction induces metabolic and mitochondrial compromise.
Sahin E, Colla S, Liesa M, Moslehi J, Müller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, Shukla SA, Jaskelioff M, Martin ES, Heffernan TP, Protopopov A, Ivanova E, Mahoney JE, Kost-Alimova M, Perry SR, Bronson R, Liao R, Mulligan R, Shirihai OS, Chin L, DePinho RA
(2011) Nature 470: 359-65 - Epidermal sensing of oxygen is essential for systemic hypoxic response.
Boutin AT, Weidemann A, Fu Z, Mesropian L, Gradin K, Jamora C, Wiesener M, Eckardt KU, Koch CJ, Ellies LG, Haddad G, Haase VH, Simon MC, Poellinger L, Powell FL, Johnson RS
(2008) Cell 133: 223-34 - Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.
Emerling BM, Hurov JB, Poulogiannis G, Tsukazawa KS, Choo-Wing R, Wulf GM, Bell EL, Shim HS, Lamia KA, Rameh LE, Bellinger G, Sasaki AT, Asara JM, Yuan X, Bullock A, Denicola GM, Song J, Brown V, Signoretti S, Cantley LC
(2013) Cell 155: 844-57 - Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.
Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA
(2013) Cell 155: 1624-38 - Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment.
Anderson AR, Weaver AM, Cummings PT, Quaranta V
(2006) Cell 127: 905-15 - Colonocyte metabolism shapes the gut microbiota.
Litvak Y, Byndloss MX, Bäumler AJ
(2018) Science 362: - Suppression of aging in mice by the hormone Klotho.
Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, Kuro-o M
(2005) Science 309: 1829-33 - Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity.
Uno K, Katagiri H, Yamada T, Ishigaki Y, Ogihara T, Imai J, Hasegawa Y, Gao J, Kaneko K, Iwasaki H, Ishihara H, Sasano H, Inukai K, Mizuguchi H, Asano T, Shiota M, Nakazato M, Oka Y
(2006) Science 312: 1656-9 - Effect of transendocardial delivery of autologous bone marrow mononuclear cells on functional capacity, left ventricular function, and perfusion in chronic heart failure: the FOCUS-CCTRN trial.
Perin EC, Willerson JT, Pepine CJ, Henry TD, Ellis SG, Zhao DX, Silva GV, Lai D, Thomas JD, Kronenberg MW, Martin AD, Anderson RD, Traverse JH, Penn MS, Anwaruddin S, Hatzopoulos AK, Gee AP, Taylor DA, Cogle CR, Smith D, Westbrook L, Chen J, Handberg E, Olson RE, Geither C, Bowman S, Francescon J, Baraniuk S, Piller LB, Simpson LM, Loghin C, Aguilar D, Richman S, Zierold C, Bettencourt J, Sayre SL, Vojvodic RW, Skarlatos SI, Gordon DJ, Ebert RF, Kwak M, Moyé LA, Simari RD, Cardiovascular Cell Therapy Research Network (CCTRN)
(2012) JAMA 307: 1717-26 - A channel to neurodegeneration.
Deutch AY, Winder DG
(2006) Nat Med 12: 17-8 - Training improves multitasking performance by increasing the speed of information processing in human prefrontal cortex.
Dux PE, Tombu MN, Harrison S, Rogers BP, Tong F, Marois R
(2009) Neuron 63: 127-38 - The neural correlates of third-party punishment.
Buckholtz JW, Asplund CL, Dux PE, Zald DH, Gore JC, Jones OD, Marois R
(2008) Neuron 60: 930-40 - Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M Muscarinic Receptor.
Moehle MS, Pancani T, Byun N, Yohn SE, Wilson GH, Dickerson JW, Remke DH, Xiang Z, Niswender CM, Wess J, Jones CK, Lindsley CW, Rook JM, Conn PJ
(2017) Neuron 96: 1358-1372.e4 - Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction.
Silberman GA, Fan TH, Liu H, Jiao Z, Xiao HD, Lovelock JD, Boulden BM, Widder J, Fredd S, Bernstein KE, Wolska BM, Dikalov S, Harrison DG, Dudley SC
(2010) Circulation 121: 519-28 - Vascular oxidant stress enhances progression and angiogenesis of experimental atheroma.
Khatri JJ, Johnson C, Magid R, Lessner SM, Laude KM, Dikalov SI, Harrison DG, Sung HJ, Rong Y, Galis ZS
(2004) Circulation 109: 520-5 - Antioxidants and myocardial contractility: illuminating the "Dark Side" of beta-adrenergic receptor activation?
Givertz MM, Sawyer DB, Colucci WS
(2001) Circulation 103: 782-3 - Recognition and Initial Management of Fulminant Myocarditis: A Scientific Statement From the American Heart Association.
Kociol RD, Cooper LT, Fang JC, Moslehi JJ, Pang PS, Sabe MA, Shah RV, Sims DB, Thiene G, Vardeny O, American Heart Association Heart Failure and Transplantation Committee of the Council on Clinical Cardiology
(2020) Circulation 141: e69-e92 - Berlin Heart EXCOR pediatric ventricular assist device for bridge to heart transplantation in US children.
Almond CS, Morales DL, Blackstone EH, Turrentine MW, Imamura M, Massicotte MP, Jordan LC, Devaney EJ, Ravishankar C, Kanter KR, Holman W, Kroslowitz R, Tjossem C, Thuita L, Cohen GA, Buchholz H, St Louis JD, Nguyen K, Niebler RA, Walters HL, Reemtsen B, Wearden PD, Reinhartz O, Guleserian KJ, Mitchell MB, Bleiweis MS, Canter CE, Humpl T
(2013) Circulation 127: 1702-11 - Altered functional and structural connectivity in a schizophrenia patient with complete agenesis of the corpus callosum.
Rane S, Kose S, Gore JC, Heckers S
(2013) Am J Psychiatry 170: 122-3 - MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation.
Lee KM, Giltnane JM, Balko JM, Schwarz LJ, Guerrero-Zotano AL, Hutchinson KE, Nixon MJ, Estrada MV, Sánchez V, Sanders ME, Lee T, Gómez H, Lluch A, Pérez-Fidalgo JA, Wolf MM, Andrejeva G, Rathmell JC, Fesik SW, Arteaga CL
(2017) Cell Metab 26: 633-647.e7 - Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery disease.
Guzik TJ, Chen W, Gongora MC, Guzik B, Lob HE, Mangalat D, Hoch N, Dikalov S, Rudzinski P, Kapelak B, Sadowski J, Harrison DG
(2008) J Am Coll Cardiol 52: 1803-9 - The neural basis of relational memory deficits in schizophrenia.
Ongür D, Cullen TJ, Wolf DH, Rohan M, Barreira P, Zalesak M, Heckers S
(2006) Arch Gen Psychiatry 63: 356-65 - Molecular aspects of sickle cell disease.
Waterman MR, Cottam GL
(1976) Angew Chem Int Ed Engl 15: 749-57 - Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans.
Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin CT, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD
(2009) J Clin Invest 119: 573-81 - Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin.
Farsijani NM, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, Ikizler TA, O'Connor PM, Haase VH
(2016) J Clin Invest 126: 1425-37 - Oxidized CaMKII: a "heart stopper" for the sinus node?
Huke S, Knollmann BC
(2011) J Clin Invest 121: 2975-7 - Diabetes increases mortality after myocardial infarction by oxidizing CaMKII.
Luo M, Guan X, Luczak ED, Lang D, Kutschke W, Gao Z, Yang J, Glynn P, Sossalla S, Swaminathan PD, Weiss RM, Yang B, Rokita AG, Maier LS, Efimov IR, Hund TJ, Anderson ME
(2013) J Clin Invest 123: 1262-74 - Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension.
Landmesser U, Dikalov S, Price SR, McCann L, Fukai T, Holland SM, Mitch WE, Harrison DG
(2003) J Clin Invest 111: 1201-9 - Induction of heparin-binding epidermal growth factor-like growth factor mRNA in rat kidney after acute injury.
Homma T, Sakai M, Cheng HF, Yasuda T, Coffey RJ, Harris RC
(1995) J Clin Invest 96: 1018-25 - Principles and practice of functional MRI of the human brain.
Gore JC
(2003) J Clin Invest 112: 4-9 - Frataxin deficiency in pancreatic islets causes diabetes due to loss of beta cell mass.
Ristow M, Mulder H, Pomplun D, Schulz TJ, Müller-Schmehl K, Krause A, Fex M, Puccio H, Müller J, Isken F, Spranger J, Müller-Wieland D, Magnuson MA, Möhlig M, Koenig M, Pfeiffer AF
(2003) J Clin Invest 112: 527-34 - DC isoketal-modified proteins activate T cells and promote hypertension.
Kirabo A, Fontana V, de Faria AP, Loperena R, Galindo CL, Wu J, Bikineyeva AT, Dikalov S, Xiao L, Chen W, Saleh MA, Trott DW, Itani HA, Vinh A, Amarnath V, Amarnath K, Guzik TJ, Bernstein KE, Shen XZ, Shyr Y, Chen SC, Mernaugh RL, Laffer CL, Elijovich F, Davies SS, Moreno H, Madhur MS, Roberts J, Harrison DG
(2014) J Clin Invest 124: 4642-56 - Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
Gomez IG, MacKenna DA, Johnson BG, Kaimal V, Roach AM, Ren S, Nakagawa N, Xin C, Newitt R, Pandya S, Xia TH, Liu X, Borza DB, Grafals M, Shankland SJ, Himmelfarb J, Portilla D, Liu S, Chau BN, Duffield JS
(2015) J Clin Invest 125: 141-56 - Arachidonic acid as a bioactive molecule.
Brash AR
(2001) J Clin Invest 107: 1339-45
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