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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Symporters are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Symporters.
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Publications
- Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency.
Shannon JR, Flattem NL, Jordan J, Jacob G, Black BK, Biaggioni I, Blakely RD, Robertson D
(2000) N Engl J Med 342: 541-9 - Long-term use of thiazide diuretics and risk of hip fracture.
Ray WA, Griffin MR, Downey W, Melton LJ
(1989) Lancet 1: 687-90 - Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter.
Pacholczyk T, Blakely RD, Amara SG
(1991) Nature 350: 350-4 - Deafness and imbalance associated with inactivation of the secretory Na-K-2Cl co-transporter.
Delpire E, Lu J, England R, Dull C, Thorne T
(1999) Nat Genet 22: 192-5 - The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum.
Howard HC, Mount DB, Rochefort D, Byun N, Dupré N, Lu J, Fan X, Song L, Rivière JB, Prévost C, Horst J, Simonati A, Lemcke B, Welch R, England R, Zhan FQ, Mercado A, Siesser WB, George AL, McDonald MP, Bouchard JP, Mathieu J, Delpire E, Rouleau GA
(2002) Nat Genet 32: 384-92 - Lactate Metabolism in Human Lung Tumors.
Faubert B, Li KY, Cai L, Hensley CT, Kim J, Zacharias LG, Yang C, Do QN, Doucette S, Burguete D, Li H, Huet G, Yuan Q, Wigal T, Butt Y, Ni M, Torrealba J, Oliver D, Lenkinski RE, Malloy CR, Wachsmann JW, Young JD, Kernstine K, DeBerardinis RJ
(2017) Cell 171: 358-371.e9 - Cryo-EM structures of the human cation-chloride cotransporter KCC1.
Liu S, Chang S, Han B, Xu L, Zhang M, Zhao C, Yang W, Wang F, Li J, Delpire E, Ye S, Bai XC, Guo J
(2019) Science 366: 505-508 - Regulation of chromatin remodeling by inositol polyphosphates.
Steger DJ, Haswell ES, Miller AL, Wente SR, O'Shea EK
(2003) Science 299: 114-6 - NKCC1 transporter facilitates seizures in the developing brain.
Dzhala VI, Talos DM, Sdrulla DA, Brumback AC, Mathews GC, Benke TA, Delpire E, Jensen FE, Staley KJ
(2005) Nat Med 11: 1205-13 - Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival.
Sotiriou S, Gispert S, Cheng J, Wang Y, Chen A, Hoogstraten-Miller S, Miller GF, Kwon O, Levine M, Guttentag SH, Nussbaum RL
(2002) Nat Med 8: 514-7 - Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway.
Perry JSA, Morioka S, Medina CB, Iker Etchegaray J, Barron B, Raymond MH, Lucas CD, Onengut-Gumuscu S, Delpire E, Ravichandran KS
(2019) Nat Cell Biol 21: 1532-1543 - Paradoxical effect of sibutramine on autonomic cardiovascular regulation.
Birkenfeld AL, Schroeder C, Boschmann M, Tank J, Franke G, Luft FC, Biaggioni I, Sharma AM, Jordan J
(2002) Circulation 106: 2459-65 - Clinical assessment of norepinephrine transporter blockade through biochemical and pharmacological profiles.
Vincent S, Bieck PR, Garland EM, Loghin C, Bymaster FP, Black BK, Gonzales C, Potter WZ, Robertson D
(2004) Circulation 109: 3202-7 - Trends in antihypertensive drug advertising, 1985-1996.
Wang TJ, Ausiello JC, Stafford RS
(1999) Circulation 99: 2055-7 - AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure.
Gurley SB, Riquier-Brison ADM, Schnermann J, Sparks MA, Allen AM, Haase VH, Snouwaert JN, Le TH, McDonough AA, Koller BH, Coffman TM
(2011) Cell Metab 13: 469-475 - Chloride Dysregulation, Seizures, and Cerebral Edema: A Relationship with Therapeutic Potential.
Glykys J, Dzhala V, Egawa K, Kahle KT, Delpire E, Staley K
(2017) Trends Neurosci 40: 276-294 - Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.
Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, Kim RB
(2006) Gastroenterology 130: 1793-806 - Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice.
Zhang MZ, Yao B, Wang S, Fan X, Wu G, Yang H, Yin H, Yang S, Harris RC
(2011) J Clin Invest 121: 2845-54 - Integrated compensatory network is activated in the absence of NCC phosphorylation.
Grimm PR, Lazo-Fernandez Y, Delpire E, Wall SM, Dorsey SG, Weinman EJ, Coleman R, Wade JB, Welling PA
(2015) J Clin Invest 125: 2136-50 - Role of p38 in the regulation of renal cortical cyclooxygenase-2 expression by extracellular chloride.
Cheng HF, Wang JL, Zhang MZ, McKanna JA, Harris RC
(2000) J Clin Invest 106: 681-8 - Defective presynaptic choline transport underlies hereditary motor neuropathy.
Barwick KE, Wright J, Al-Turki S, McEntagart MM, Nair A, Chioza B, Al-Memar A, Modarres H, Reilly MM, Dick KJ, Ruggiero AM, Blakely RD, Hurles ME, Crosby AH
(2012) Am J Hum Genet 91: 1103-7 - Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2.
Delpire E, Days E, Lewis LM, Mi D, Kim K, Lindsley CW, Weaver CD
(2009) Proc Natl Acad Sci U S A 106: 5383-8 - Norepinephrine transporters have channel modes of conduction.
Galli A, Blakely RD, DeFelice LJ
(1996) Proc Natl Acad Sci U S A 93: 8671-6 - Patch-clamp and amperometric recordings from norepinephrine transporters: channel activity and voltage-dependent uptake.
Galli A, Blakely RD, DeFelice LJ
(1998) Proc Natl Acad Sci U S A 95: 13260-5 - Renal cortical cyclooxygenase 2 expression is differentially regulated by angiotensin II AT(1) and AT(2) receptors.
Zhang MZ, Yao B, Cheng HF, Wang SW, Inagami T, Harris RC
(2006) Proc Natl Acad Sci U S A 103: 16045-50 - K-Cl cotransporters, cell volume homeostasis, and neurological disease.
Kahle KT, Khanna AR, Alper SL, Adragna NC, Lauf PK, Sun D, Delpire E
(2015) Trends Mol Med 21: 513-23 - Constitutively Active SPAK Causes Hyperkalemia by Activating NCC and Remodeling Distal Tubules.
Grimm PR, Coleman R, Delpire E, Welling PA
(2017) J Am Soc Nephrol 28: 2597-2606 - and Loci Associate with Plasma Osmolality.
Böger CA, Gorski M, McMahon GM, Xu H, Chang YC, van der Most PJ, Navis G, Nolte IM, de Borst MH, Zhang W, Lehne B, Loh M, Tan ST, Boerwinkle E, Grams ME, Sekula P, Li M, Wilmot B, Moon JG, Scheet P, Cucca F, Xiao X, Lyytikäinen LP, Delgado G, Grammer TB, Kleber ME, Sedaghat S, Rivadeneira F, Corre T, Kutalik Z, Bergmann S, Nielson CM, Srikanth P, Teumer A, Müller-Nurasyid M, Brockhaus AC, Pfeufer A, Rathmann W, Peters A, Matsumoto M, de Andrade M, Atkinson EJ, Robinson-Cohen C, de Boer IH, Hwang SJ, Heid IM, Gögele M, Concas MP, Tanaka T, Bandinelli S, Nalls MA, Singleton A, Tajuddin SM, Adeyemo A, Zhou J, Doumatey A, McWeeney S, Murabito J, Franceschini N, Flessner M, Shlipak M, Wilson JG, Chen G, Rotimi CN, Zonderman AB, Evans MK, Ferrucci L, Devuyst O, Pirastu M, Shuldiner A, Hicks AA, Pramstaller PP, Kestenbaum B, Kardia SLR, Turner ST, Study LC, Briske TE, Gieger C, Strauch K, Meisinger C, Meitinger T, Völker U, Nauck M, Völzke H, Vollenweider P, Bochud M, Waeber G, Kähönen M, Lehtimäki T, März W, Dehghan A, Franco OH, Uitterlinden AG, Hofman A, Taylor HA, Chambers JC, Kooner JS, Fox CS, Hitzemann R, Orwoll ES, Pattaro C, Schlessinger D, Köttgen A, Snieder H, Parsa A, Cohen DM
(2017) J Am Soc Nephrol 28: 2311-2321 - A mutation in the human norepinephrine transporter gene (SLC6A2) associated with orthostatic intolerance disrupts surface expression of mutant and wild-type transporters.
Hahn MK, Robertson D, Blakely RD
(2003) J Neurosci 23: 4470-8 - Physiological genomics of antidepressant targets: keeping the periphery in mind.
Blakely RD
(2001) J Neurosci 21: 8319-23 - NKCC1 phosphorylation stimulates neurite growth of injured adult sensory neurons.
Pieraut S, Laurent-Matha V, Sar C, Hubert T, Méchaly I, Hilaire C, Mersel M, Delpire E, Valmier J, Scamps F
(2007) J Neurosci 27: 6751-9 - Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A.
Bauman AL, Apparsundaram S, Ramamoorthy S, Wadzinski BE, Vaughan RA, Blakely RD
(2000) J Neurosci 20: 7571-8 - Molecular cloning and characterization of an L-epinephrine transporter from sympathetic ganglia of the bullfrog, Rana catesbiana.
Apparsundaram S, Moore KR, Malone MD, Hartzell HC, Blakely RD
(1997) J Neurosci 17: 2691-702 - A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity.
Sung U, Apparsundaram S, Galli A, Kahlig KM, Savchenko V, Schroeter S, Quick MW, Blakely RD
(2003) J Neurosci 23: 1697-709 - Abnormal GABAA receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice.
Sung KW, Kirby M, McDonald MP, Lovinger DM, Delpire E
(2000) J Neurosci 20: 7531-8
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