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•  Julie Bastarache

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Publications

• The transcription factor NF-ATc is essential for cardiac valve formation.
  Ranger AM, Grusby MJ, Hodge MR, Gravallese EM, de la Brousse FC, Hoey T, Mickanin C, Baldwin HS, Glimcher LH
  (1998) Nature 392: 186-90
• LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.
  Wang X, Abraham S, McKenzie JAG, Jeffs N, Swire M, Tripathi VB, Luhmann UFO, Lange CAK, Zhai Z, Arthur HM, Bainbridge J, Moss SE, Greenwood J
  (2013) Nature 499: 306-11
• Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide.
  Myers PR, Minor RL, Guerra R, Bates JN, Harrison DG
  (1990) Nature 345: 161-3
• Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension.
  Germain M, Eyries M, Montani D, Poirier O, Girerd B, Dorfmüller P, Coulet F, Nadaud S, Maugenre S, Guignabert C, Carpentier W, Vonk-Noordegraaf A, Lévy M, Chaouat A, Lambert JC, Bertrand M, Dupuy AM, Letenneur L, Lathrop M, Amouyel P, de Ravel TJ, Delcroix M, Austin ED, Robbins IM, Hemnes AR, Loyd JE, Berman-Rosenzweig E, Barst RJ, Chung WK, Simonneau G, Trégouët DA, Humbert M, Soubrier F
  (2013) Nat Genet 45: 518-21
• Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells.
  Lippmann ES, Azarin SM, Kay JE, Nessler RA, Wilson HK, Al-Ahmad A, Palecek SP, Shusta EV
  (2012) Nat Biotechnol 30: 783-91
• Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart.
  Brown CB, Boyer AS, Runyan RB, Barnett JV
  (1999) Science 283: 2080-2
• The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity.
  Pruenster M, Mudde L, Bombosi P, Dimitrova S, Zsak M, Middleton J, Richmond A, Graham GJ, Segerer S, Nibbs RJ, Rot A
  (2009) Nat Immunol 10: 101-8
• Embryonic endothelial progenitor cells armed with a suicide gene target hypoxic lung metastases after intravenous delivery.
  Wei J, Blum S, Unger M, Jarmy G, Lamparter M, Geishauser A, Vlastos GA, Chan G, Fischer KD, Rattat D, Debatin KM, Hatzopoulos AK, Beltinger C
  (2004) Cancer Cell 5: 477-88
• Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis.
  Yang L, DeBusk LM, Fukuda K, Fingleton B, Green-Jarvis B, Shyr Y, Matrisian LM, Carbone DP, Lin PC
  (2004) Cancer Cell 6: 409-21
• Viral nanoparticles as tools for intravital vascular imaging.
  Lewis JD, Destito G, Zijlstra A, Gonzalez MJ, Quigley JP, Manchester M, Stuhlmann H
  (2006) Nat Med 12: 354-60
• The perivascular niche regulates breast tumour dormancy.
  Ghajar CM, Peinado H, Mori H, Matei IR, Evason KJ, Brazier H, Almeida D, Koller A, Hajjar KA, Stainier DY, Chen EI, Lyden D, Bissell MJ
  (2013) Nat Cell Biol 15: 807-17
• A Metabolic Basis for Endothelial-to-Mesenchymal Transition.
  Xiong J, Kawagishi H, Yan Y, Liu J, Wells QS, Edmunds LR, Fergusson MM, Yu ZX, Rovira II, Brittain EL, Wolfgang MJ, Jurczak MJ, Fessel JP, Finkel T
  (2018) Mol Cell 69: 689-698.e7
• NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis.
  Brown JD, Lin CY, Duan Q, Griffin G, Federation A, Paranal RM, Bair S, Newton G, Lichtman A, Kung A, Yang T, Wang H, Luscinskas FW, Croce K, Bradner JE, Plutzky J
  (2014) Mol Cell 56: 219-231
• Cross-sectional relations of multiple biomarkers from distinct biological pathways to brachial artery endothelial function.
  Kathiresan S, Gona P, Larson MG, Vita JA, Mitchell GF, Tofler GH, Levy D, Newton-Cheh C, Wang TJ, Benjamin EJ, Vasan RS
  (2006) Circulation 113: 938-45
• Ischemia-reperfusion impairs endothelium-dependent relaxation of coronary microvessels but does not affect large arteries.
  Quillen JE, Sellke FW, Brooks LA, Harrison DG
  (1990) Circulation 82: 586-94
• Endothelium-dependent vascular relaxation is abnormal in the coronary microcirculation of atherosclerotic primates.
  Sellke FW, Armstrong ML, Harrison DG
  (1990) Circulation 81: 1586-93
• Angiotensin-converting enzyme inhibition increases human vascular tissue-type plasminogen activator release through endogenous bradykinin.
  Pretorius M, Rosenbaum D, Vaughan DE, Brown NJ
  (2003) Circulation 107: 579-85
• Low-grade albuminuria and the risks of hypertension and blood pressure progression.
  Wang TJ, Evans JC, Meigs JB, Rifai N, Fox CS, D'Agostino RB, Levy D, Vasan RS
  (2005) Circulation 111: 1370-6
• Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation.
  Spiekermann S, Landmesser U, Dikalov S, Bredt M, Gamez G, Tatge H, Reepschläger N, Hornig B, Drexler H, Harrison DG
  (2003) Circulation 107: 1383-9
• Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine-oxidase and extracellular superoxide dismutase.
  Landmesser U, Spiekermann S, Dikalov S, Tatge H, Wilke R, Kohler C, Harrison DG, Hornig B, Drexler H
  (2002) Circulation 106: 3073-8
• Dietary correction of hypercholesterolemia in the rabbit normalizes endothelial superoxide anion production.
  Ohara Y, Peterson TE, Sayegh HS, Subramanian RR, Wilcox JN, Harrison DG
  (1995) Circulation 92: 898-903
• Current perspectives on statins.
  Maron DJ, Fazio S, Linton MF
  (2000) Circulation 101: 207-13
• Bradykinin stimulates tissue plasminogen activator release from human forearm vasculature through B(2) receptor-dependent, NO synthase-independent, and cyclooxygenase-independent pathway.
  Brown NJ, Gainer JV, Murphey LJ, Vaughan DE
  (2000) Circulation 102: 2190-6
• Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation.
  Miriyala S, Gongora Nieto MC, Mingone C, Smith D, Dikalov S, Harrison DG, Jo H
  (2006) Circulation 113: 2818-25
• Endothelial modulation of the coronary vasculature in vessels perfused via mature collaterals.
  Sellke FW, Quillen JE, Brooks LA, Harrison DG
  (1990) Circulation 81: 1938-47
• Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study.
  Pikula A, Beiser AS, DeCarli C, Himali JJ, Debette S, Au R, Selhub J, Toffler GH, Wang TJ, Meigs JB, Kelly-Hayes M, Kase CS, Wolf PA, Vasan RS, Seshadri S
  (2012) Circulation 125: 2100-7
• Release of nitrogen oxides from cultured bovine aortic endothelial cells is not impaired by calcium channel antagonists.
  Mügge A, Peterson T, Harrison DG
  (1991) Circulation 83: 1404-9
• Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery disease.
  Guzik TJ, Chen W, Gongora MC, Guzik B, Lob HE, Mangalat D, Hoch N, Dikalov S, Rudzinski P, Kapelak B, Sadowski J, Harrison DG
  (2008) J Am Coll Cardiol 52: 1803-9
• Regulation of local tissue-type plasminogen activator release by endothelium-dependent and endothelium-independent agonists in human vasculature.
  Stein CM, Brown N, Vaughan DE, Lang CC, Wood AJ
  (1998) J Am Coll Cardiol 32: 117-22
• Cellular and molecular pathobiology of pulmonary arterial hypertension.
  Humbert M, Morrell NW, Archer SL, Stenmark KR, MacLean MR, Lang IM, Christman BW, Weir EK, Eickelberg O, Voelkel NF, Rabinovitch M
  (2004) J Am Coll Cardiol 43: 13S-24S
• Insights into (the interstitium of) degenerative aortic valve disease.
  Merryman WD
  (2008) J Am Coll Cardiol 51: 1415; author reply 1416
• Multistep nature of microvascular recruitment of ex vivo-expanded embryonic endothelial progenitor cells during tumor angiogenesis.
  Vajkoczy P, Blum S, Lamparter M, Mailhammer R, Erber R, Engelhardt B, Vestweber D, Hatzopoulos AK
  (2003) J Exp Med 197: 1755-65
• CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer.
  Wang D, Wang H, Brown J, Daikoku T, Ning W, Shi Q, Richmond A, Strieter R, Dey SK, DuBois RN
  (2006) J Exp Med 203: 941-51
• Forearm beta adrenergic receptor-mediated vasodilation is impaired, without alteration of forearm norepinephrine spillover, in borderline hypertension.
  Stein CM, Nelson R, Deegan R, He H, Wood M, Wood AJ
  (1995) J Clin Invest 96: 579-85
• Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells.
  Jackson KA, Majka SM, Wang H, Pocius J, Hartley CJ, Majesky MW, Entman ML, Michael LH, Hirschi KK, Goodell MA
  (2001) J Clin Invest 107: 1395-402
• Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration.
  Majka SM, Jackson KA, Kienstra KA, Majesky MW, Goodell MA, Hirschi KK
  (2003) J Clin Invest 111: 71-9
• From ST segments to endothelial pathophysiology: hypercholesterolemia and endothelial superoxide production.
  Harrison DG
  (2014) J Clin Invest 124: 473-5
• Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance.
  Münzel T, Sayegh H, Freeman BA, Tarpey MM, Harrison DG
  (1995) J Clin Invest 95: 187-94
• Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis.
  Harrison DG, Armstrong ML, Freiman PC, Heistad DD
  (1987) J Clin Invest 80: 1808-11
• Fibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate.
  Weiss HJ, Hawiger J, Ruggeri ZM, Turitto VT, Thiagarajan P, Hoffmann T
  (1989) J Clin Invest 83: 288-97