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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Pulmonary Alveoli are shown below. Double-click or tap a node for more information.
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Publications
- Release of prostaglandin D2 into human airways during acute antigen challenge.
Murray JJ, Tonnel AB, Brash AR, Roberts LJ, Gosset P, Workman R, Capron A, Oates JA
(1986) N Engl J Med 315: 800-4 - Prevention of intraoperative awareness.
Wilson SH, McEvoy MD
(2011) N Engl J Med 365: 2032-3; author reply 2034 - ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization.
Lee Y, Fryer JD, Kang H, Crespo-Barreto J, Bowman AB, Gao Y, Kahle JJ, Hong JS, Kheradmand F, Orr HT, Finegold MJ, Zoghbi HY
(2011) Dev Cell 21: 746-57 - Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD.
Benjamin JT, Plosa EJ, Sucre JM, van der Meer R, Dave S, Gutor S, Nichols DS, Gulleman PM, Jetter CS, Han W, Xin M, Dinella PC, Catanzarite A, Kook S, Dolma K, Lal CV, Gaggar A, Blalock JE, Newcomb DC, Richmond BW, Kropski JA, Young LR, Guttentag SH, Blackwell TS
(2021) J Clin Invest 131: - Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.
Blackwell TS, Tager AM, Borok Z, Moore BB, Schwartz DA, Anstrom KJ, Bar-Joseph Z, Bitterman P, Blackburn MR, Bradford W, Brown KK, Chapman HA, Collard HR, Cosgrove GP, Deterding R, Doyle R, Flaherty KR, Garcia CK, Hagood JS, Henke CA, Herzog E, Hogaboam CM, Horowitz JC, King TE, Loyd JE, Lawson WE, Marsh CB, Noble PW, Noth I, Sheppard D, Olsson J, Ortiz LA, O'Riordan TG, Oury TD, Raghu G, Roman J, Sime PJ, Sisson TH, Tschumperlin D, Violette SM, Weaver TE, Wells RG, White ES, Kaminski N, Martinez FJ, Wynn TA, Thannickal VJ, Eu JP
(2014) Am J Respir Crit Care Med 189: 214-22 - Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis.
Tanjore H, Xu XC, Polosukhin VV, Degryse AL, Li B, Han W, Sherrill TP, Plieth D, Neilson EG, Blackwell TS, Lawson WE
(2009) Am J Respir Crit Care Med 180: 657-65 - β-catenin in the alveolar epithelium protects from lung fibrosis after intratracheal bleomycin.
Tanjore H, Degryse AL, Crossno PF, Xu XC, McConaha ME, Jones BR, Polosukhin VV, Bryant AJ, Cheng DS, Newcomb DC, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE
(2013) Am J Respir Crit Care Med 187: 630-9 - The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome.
Young LR, Gulleman PM, Bridges JP, Weaver TE, Deutsch GH, Blackwell TS, McCormack FX
(2012) Am J Respir Crit Care Med 186: 1014-24 - Novel Method for Noninvasive Sampling of the Distal Airspace in Acute Respiratory Distress Syndrome.
McNeil JB, Shaver CM, Kerchberger VE, Russell DW, Grove BS, Warren MA, Wickersham NE, Ware LB, McDonald WH, Bastarache JA
(2018) Am J Respir Crit Care Med 197: 1027-1035 - Early alveolar epithelial dysfunction promotes lung inflammation in a mouse model of Hermansky-Pudlak syndrome.
Atochina-Vasserman EN, Bates SR, Zhang P, Abramova H, Zhang Z, Gonzales L, Tao JQ, Gochuico BR, Gahl W, Guo CJ, Gow AJ, Beers MF, Guttentag S
(2011) Am J Respir Crit Care Med 184: 449-58 - Let It Be: microRNAs impact interstitial lung disease.
Lawson WE, Blackwell TS, Gauldie J
(2011) Am J Respir Crit Care Med 183: 1-2 - Proteomic patterns of preinvasive bronchial lesions.
Rahman SM, Shyr Y, Yildiz PB, Gonzalez AL, Li H, Zhang X, Chaurand P, Yanagisawa K, Slovis BS, Miller RF, Ninan M, Miller YE, Franklin WA, Caprioli RM, Carbone DP, Massion PP
(2005) Am J Respir Crit Care Med 172: 1556-62 - Chemotactic gradients predict neutrophilic alveolitis in endotoxin-treated rats.
Blackwell TS, Lancaster LH, Blackwell TR, Venkatakrishnan A, Christman JW
(1999) Am J Respir Crit Care Med 159: 1644-52 - Molecular and functional defects in kidneys of mice lacking collagen alpha 3(IV): implications for Alport syndrome.
Miner JH, Sanes JR
(1996) J Cell Biol 135: 1403-13 - K-ras oncogene activation in atypical alveolar hyperplasias of the human lung.
Westra WH, Baas IO, Hruban RH, Askin FB, Wilson K, Offerhaus GJ, Slebos RJ
(1996) Cancer Res 56: 2224-8 - Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis.
Forrester E, Chytil A, Bierie B, Aakre M, Gorska AE, Sharif-Afshar AR, Muller WJ, Moses HL
(2005) Cancer Res 65: 2296-302 - Low levels of tissue factor lead to alveolar haemorrhage, potentiating murine acute lung injury and oxidative stress.
Bastarache JA, Sebag SC, Clune JK, Grove BS, Lawson WE, Janz DR, Roberts LJ, Dworski R, Mackman N, Ware LB
(2012) Thorax 67: 1032-9 - The alveolar epithelium can initiate the extrinsic coagulation cascade through expression of tissue factor.
Bastarache JA, Wang L, Geiser T, Wang Z, Albertine KH, Matthay MA, Ware LB
(2007) Thorax 62: 608-16 - Determining the aetiology of pulmonary oedema by the oedema fluid-to-plasma protein ratio.
Ware LB, Fremont RD, Bastarache JA, Calfee CS, Matthay MA
(2010) Eur Respir J 35: 331-7 - Haemosiderin-laden macrophages in the bronchoalveolar lavage fluid of patients with diffuse alveolar damage.
Maldonado F, Parambil JG, Yi ES, Decker PA, Ryu JH
(2009) Eur Respir J 33: 1361-6 - Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization.
Plosa EJ, Young LR, Gulleman PM, Polosukhin VV, Zaynagetdinov R, Benjamin JT, Im AM, van der Meer R, Gleaves LA, Bulus N, Han W, Prince LS, Blackwell TS, Zent R
(2014) Development 141: 4751-62 - Sirolimus-associated diffuse alveolar hemorrhage.
Vlahakis NE, Rickman OB, Morgenthaler T
(2004) Mayo Clin Proc 79: 541-5 - Murine membranous nephropathy: immunization with α3(IV) collagen fragment induces subepithelial immune complexes and FcγR-independent nephrotic syndrome.
Zhang JJ, Malekpour M, Luo W, Ge L, Olaru F, Wang XP, Bah M, Sado Y, Heidet L, Kleinau S, Fogo AB, Borza DB
(2012) J Immunol 188: 3268-77 - Pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space.
Maus UA, Srivastava M, Paton JC, Mack M, Everhart MB, Blackwell TS, Christman JW, Schlöndorff D, Seeger W, Lohmeyer J
(2004) J Immunol 173: 1307-12 - Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: role of the CCL2-CCR2 axis.
Maus UA, Waelsch K, Kuziel WA, Delbeck T, Mack M, Blackwell TS, Christman JW, Schlöndorff D, Seeger W, Lohmeyer J
(2003) J Immunol 170: 3273-8 - IL-17A and TNF-α exert synergistic effects on expression of CXCL5 by alveolar type II cells in vivo and in vitro.
Liu Y, Mei J, Gonzales L, Yang G, Dai N, Wang P, Zhang P, Favara M, Malcolm KC, Guttentag S, Worthen GS
(2011) J Immunol 186: 3197-205 - Airway and lung in sepsis.
Martin GS, Bernard GR, International Sepsis Forum
(2001) Intensive Care Med 27 Suppl 1: S63-79 - Acute lung injury edema fluid decreases net fluid transport across human alveolar epithelial type II cells.
Lee JW, Fang X, Dolganov G, Fremont RD, Bastarache JA, Ware LB, Matthay MA
(2007) J Biol Chem 282: 24109-19 - Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress.
Tanjore H, Cheng DS, Degryse AL, Zoz DF, Abdolrasulnia R, Lawson WE, Blackwell TS
(2011) J Biol Chem 286: 30972-30980 - Loss of PECAM-1 function impairs alveolarization.
DeLisser HM, Helmke BP, Cao G, Egan PM, Taichman D, Fehrenbach M, Zaman A, Cui Z, Mohan GS, Baldwin HS, Davies PF, Savani RC
(2006) J Biol Chem 281: 8724-31 - Intratracheal administration of liposomal clodronate accelerates alveolar macrophage reconstitution following fetal liver transplantation.
Everhart MB, Han W, Parman KS, Polosukhin VV, Zeng H, Sadikot RT, Li B, Yull FE, Christman JW, Blackwell TS
(2005) J Leukoc Biol 77: 173-80 - p120-catenin expressed in alveolar type II cells is essential for the regulation of lung innate immune response.
Chignalia AZ, Vogel SM, Reynolds AB, Mehta D, Dull RO, Minshall RD, Malik AB, Liu Y
(2015) Am J Pathol 185: 1251-63 - Regulation of alveolar procoagulant activity and permeability in direct acute lung injury by lung epithelial tissue factor.
Shaver CM, Grove BS, Putz ND, Clune JK, Lawson WE, Carnahan RH, Mackman N, Ware LB, Bastarache JA
(2015) Am J Respir Cell Mol Biol 53: 719-27 - Novel role of the human alveolar epithelium in regulating intra-alveolar coagulation.
Wang L, Bastarache JA, Wickersham N, Fang X, Matthay MA, Ware LB
(2007) Am J Respir Cell Mol Biol 36: 497-503 - Surfactant protein B in type II pneumocytes and intra-alveolar surfactant forms of human lungs.
Brasch F, Johnen G, Winn-Brasch A, Guttentag SH, Schmiedl A, Kapp N, Suzuki Y, Müller KM, Richter J, Hawgood S, Ochs M
(2004) Am J Respir Cell Mol Biol 30: 449-58 - Animal models of fibrotic lung disease.
B Moore B, Lawson WE, Oury TD, Sisson TH, Raghavendran K, Hogaboam CM
(2013) Am J Respir Cell Mol Biol 49: 167-79 - Alveolar basement membrane: molecular properties of the noncollagenous domain (hexamer) of collagen IV and its reactivity with Goodpasture autoantibodies.
Gunwar S, Bejarano PA, Kalluri R, Langeveld JP, Wisdom BJ, Noelken ME, Hudson BG
(1991) Am J Respir Cell Mol Biol 5: 107-12 - Prenatal Diagnosis of Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins.
Prothro SL, Plosa E, Markham M, Szafranski P, Stankiewicz P, Killen SA
(2016) J Pediatr 170: 317-8 - Regulation of Acinetobacter baumannii biofilm formation.
Gaddy JA, Actis LA
(2009) Future Microbiol 4: 273-8 - Expression of cytochromes P450 1A1 and 1B1 in human lung from smokers, non-smokers, and ex-smokers.
Kim JH, Sherman ME, Curriero FC, Guengerich FP, Strickland PT, Sutter TR
(2004) Toxicol Appl Pharmacol 199: 210-9
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