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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Publications
- Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor.
Goodman OB, Krupnick JG, Santini F, Gurevich VV, Penn RB, Gagnon AW, Keen JH, Benovic JL
(1996) Nature 383: 447-50 - The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S.
Noel JP, Hamm HE, Sigler PB
(1993) Nature 366: 654-63 - GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4.
Sondek J, Lambright DG, Noel JP, Hamm HE, Sigler PB
(1994) Nature 372: 276-9 - Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide.
Myers PR, Minor RL, Guerra R, Bates JN, Harrison DG
(1990) Nature 345: 161-3 - The 2.0 A crystal structure of a heterotrimeric G protein.
Lambright DG, Sondek J, Bohm A, Skiba NP, Hamm HE, Sigler PB
(1996) Nature 379: 311-9 - Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein.
Lambright DG, Noel JP, Hamm HE, Sigler PB
(1994) Nature 369: 621-8 - M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity.
De Souza AT, Hankins GR, Washington MK, Orton TC, Jirtle RL
(1995) Nat Genet 11: 447-9 - ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity.
Brown HA, Gutowski S, Moomaw CR, Slaughter C, Sternweis PC
(1993) Cell 75: 1137-44 - The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2.
Wall MA, Coleman DE, Lee E, Iñiguez-Lluhi JA, Posner BA, Gilman AG, Sprang SR
(1995) Cell 83: 1047-58 - The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation.
Hirsch JA, Schubert C, Gurevich VV, Sigler PB
(1999) Cell 97: 257-69 - Expression of bovine 17 alpha-hydroxylase cytochrome P-450 cDNA in nonsteroidogenic (COS 1) cells.
Zuber MX, Simpson ER, Waterman MR
(1986) Science 234: 1258-61 - A sulfilimine bond identified in collagen IV.
Vanacore R, Ham AJ, Voehler M, Sanders CR, Conrads TP, Veenstra TD, Sharpless KB, Dawson PE, Hudson BG
(2009) Science 325: 1230-4 - ATP serves as a negative feedback inhibitor of voltage-gated Ca2+ channel currents in cultured bovine adrenal chromaffin cells.
Currie KP, Fox AP
(1996) Neuron 16: 1027-36 - Release of nitrogen oxides from cultured bovine aortic endothelial cells is not impaired by calcium channel antagonists.
Mügge A, Peterson T, Harrison DG
(1991) Circulation 83: 1404-9 - Influence of Arrestin on the Photodecay of Bovine Rhodopsin.
Chatterjee D, Eckert CE, Slavov C, Saxena K, Fürtig B, Sanders CR, Gurevich VV, Wachtveitl J, Schwalbe H
(2015) Angew Chem Int Ed Engl 54: 13555-60 - The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents.
Carlomagno T, Blommers MJ, Meiler J, Jahnke W, Schupp T, Petersen F, Schinzer D, Altmann KH, Griesinger C
(2003) Angew Chem Int Ed Engl 42: 2511-5 - Proteolytic surface functionalization enhances in vitro magnetic nanoparticle mobility through extracellular matrix.
Kuhn SJ, Finch SK, Hallahan DE, Giorgio TD
(2006) Nano Lett 6: 306-12 - Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase.
Nishida K, Harrison DG, Navas JP, Fisher AA, Dockery SP, Uematsu M, Nerem RM, Alexander RW, Murphy TJ
(1992) J Clin Invest 90: 2092-6 - IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation.
Yamaoka-Tojo M, Ushio-Fukai M, Hilenski L, Dikalov SI, Chen YE, Tojo T, Fukai T, Fujimoto M, Patrushev NA, Wang N, Kontos CD, Bloom GS, Alexander RW
(2004) Circ Res 95: 276-83 - Therapeutic targeting of mitochondrial superoxide in hypertension.
Dikalova AE, Bikineyeva AT, Budzyn K, Nazarewicz RR, McCann L, Lewis W, Harrison DG, Dikalov SI
(2010) Circ Res 107: 106-16 - Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction.
Doughan AK, Harrison DG, Dikalov SI
(2008) Circ Res 102: 488-96 - Biosynthesis and in vivo localization of the decapentaplegic-Vg-related protein, DVR-6 (bone morphogenetic protein-6).
Wall NA, Blessing M, Wright CV, Hogan BL
(1993) J Cell Biol 120: 493-502 - Extracellular chloride signals collagen IV network assembly during basement membrane formation.
Cummings CF, Pedchenko V, Brown KL, Colon S, Rafi M, Jones-Paris C, Pokydeshava E, Liu M, Pastor-Pareja JC, Stothers C, Ero-Tolliver IA, McCall AS, Vanacore R, Bhave G, Santoro S, Blackwell TS, Zent R, Pozzi A, Hudson BG
(2016) J Cell Biol 213: 479-94 - Surface relocation of alpha 6 beta 4 integrins and assembly of hemidesmosomes in an in vitro model of wound healing.
Kurpakus MA, Quaranta V, Jones JC
(1991) J Cell Biol 115: 1737-50 - Elongation arrest is not a prerequisite for secretory protein translocation across the microsomal membrane.
Siegel V, Walter P
(1985) J Cell Biol 100: 1913-21 - Superoxide reaction with tyrosyl radicals generates para-hydroperoxy and para-hydroxy derivatives of tyrosine.
Möller MN, Hatch DM, Kim HY, Porter NA
(2012) J Am Chem Soc 134: 16773-80 - CpG island density and its correlations with genomic features in mammalian genomes.
Han L, Su B, Li WH, Zhao Z
(2008) Genome Biol 9: R79 - Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension.
Newman JH, Holt TN, Cogan JD, Womack B, Phillips JA, Li C, Kendall Z, Stenmark KR, Thomas MG, Brown RD, Riddle SR, West JD, Hamid R
(2015) Nat Commun 6: 6863 - Structural basis of arrestin-3 activation and signaling.
Chen Q, Perry NA, Vishnivetskiy SA, Berndt S, Gilbert NC, Zhuo Y, Singh PK, Tholen J, Ohi MD, Gurevich EV, Brautigam CA, Klug CS, Gurevich VV, Iverson TM
(2017) Nat Commun 8: 1427 - Structure and function of the visual arrestin oligomer.
Hanson SM, Van Eps N, Francis DJ, Altenbach C, Vishnivetskiy SA, Arshavsky VY, Klug CS, Hubbell WL, Gurevich VV
(2007) EMBO J 26: 1726-36 - The affinity of signal recognition particle for presecretory proteins is dependent on nascent chain length.
Siegel V, Walter P
(1988) EMBO J 7: 1769-75 - Evolutionarily divergent electron donor proteins interact with P450MT2 through the same helical domain but different contact points.
Anandatheerthavarada HK, Amuthan G, Biswas G, Robin MA, Murali R, Waterman MR, Avadhani NG
(2001) EMBO J 20: 2394-403 - Definition of cytochrome c binding domains by chemical modification: kinetics of reaction with beef mitochondrial reductase and functional organization of the respiratory chain.
Speck SH, Ferguson-Miller S, Osheroff N, Margoliash E
(1979) Proc Natl Acad Sci U S A 76: 155-9 - LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin.
Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E
(2008) Proc Natl Acad Sci U S A 105: 8032-7 - Inhibition of the mitogenic effects of plasma by a monoclonal antibody to somatomedin C.
Russell WE, Van Wyk JJ, Pledger WJ
(1984) Proc Natl Acad Sci U S A 81: 2389-92 - Evidence for a higher molecular weight precursor of cholesterol side-chain-cleavage cytochrome P-450 and induction of mitochondrial and cytosolic proteins by corticotropin in adult bovine adrenal cells.
DuBois RN, Simpson ER, Tuckey J, Lambeth JD, Waterman MR
(1981) Proc Natl Acad Sci U S A 78: 1028-32 - Expression at the cell surface of biologically active fusion and hemagglutinin/neuraminidase proteins of the paramyxovirus simian virus 5 from cloned cDNA.
Paterson RG, Hiebert SW, Lamb RA
(1985) Proc Natl Acad Sci U S A 82: 7520-4 - Molecular cloning and transformation of cyclodiene resistance in Drosophila: an invertebrate gamma-aminobutyric acid subtype A receptor locus.
Ffrench-Constant RH, Mortlock DP, Shaffer CD, MacIntyre RJ, Roush RT
(1991) Proc Natl Acad Sci U S A 88: 7209-13 - The role of dynamic palmitoylation in Ca2+ channel inactivation.
Hurley JH, Cahill AL, Currie KP, Fox AP
(2000) Proc Natl Acad Sci U S A 97: 9293-8
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