Keyword Connections

•  Dorin Bogdan Borza

Resources

• No matching connections

Communities

• No matching connections

Publications

• Molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis.
  Pedchenko V, Bondar O, Fogo AB, Vanacore R, Voziyan P, Kitching AR, Wieslander J, Kashtan C, Borza DB, Neilson EG, Wilson CB, Hudson BG
  (2010) N Engl J Med 363: 343-54
• Alport's syndrome, Goodpasture's syndrome, and type IV collagen.
  Hudson BG, Tryggvason K, Sundaramoorthy M, Neilson EG
  (2003) N Engl J Med 348: 2543-56
• Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
  Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Ramarathinam SH, Eggenhuizen PJ, Loh KL, Watson KA, Gan PY, Alikhan MA, Dudek NL, Handel A, Hudson BG, Fugger L, Power DA, Holt SG, Coates PT, Gregersen JW, Purcell AW, Holdsworth SR, La Gruta NL, Reid HH, Rossjohn J, Kitching AR
  (2017) Nature 545: 243-247
• Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals.
  Fox MA, Sanes JR, Borza DB, Eswarakumar VP, Fässler R, Hudson BG, John SW, Ninomiya Y, Pedchenko V, Pfaff SL, Rheault MN, Sado Y, Segal Y, Werle MJ, Umemori H
  (2007) Cell 129: 179-93
• A sulfilimine bond identified in collagen IV.
  Vanacore R, Ham AJ, Voehler M, Sanders CR, Conrads TP, Veenstra TD, Sharpless KB, Dawson PE, Hudson BG
  (2009) Science 325: 1230-4
• Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.
  de la Croix Ndong J, Makowski AJ, Uppuganti S, Vignaux G, Ono K, Perrien DS, Joubert S, Baglio SR, Granchi D, Stevenson DA, Rios JJ, Nyman JS, Elefteriou F
  (2014) Nat Med 20: 904-10
• Re: Microfibrillar structure of type I collagen in situ.
  Okuyama K, Bächinger HP, Mizuno K, Boudko S, Engel J, Berisio R, Vitagliano L
  (2009) Acta Crystallogr D Biol Crystallogr 65: 1007-8; author reply 1009-10
• Peroxidasin forms sulfilimine chemical bonds using hypohalous acids in tissue genesis.
  Bhave G, Cummings CF, Vanacore RM, Kumagai-Cresse C, Ero-Tolliver IA, Rafi M, Kang JS, Pedchenko V, Fessler LI, Fessler JH, Hudson BG
  (2012) Nat Chem Biol 8: 784-90
• MT2-MMP-dependent release of collagen IV NC1 domains regulates submandibular gland branching morphogenesis.
  Rebustini IT, Myers C, Lassiter KS, Surmak A, Szabova L, Holmbeck K, Pedchenko V, Hudson BG, Hoffman MP
  (2009) Dev Cell 17: 482-93
• Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice.
  Scholten D, Osterreicher CH, Scholten A, Iwaisako K, Gu G, Brenner DA, Kisseleva T
  (2010) Gastroenterology 139: 987-98
• Absence of angiotensin II type 1 receptor in bone marrow-derived cells is detrimental in the evolution of renal fibrosis.
  Nishida M, Fujinaka H, Matsusaka T, Price J, Kon V, Fogo AB, Davidson JM, Linton MF, Fazio S, Homma T, Yoshida H, Ichikawa I
  (2002) J Clin Invest 110: 1859-68
• Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
  Gomez IG, MacKenna DA, Johnson BG, Kaimal V, Roach AM, Ren S, Nakagawa N, Xin C, Newitt R, Pandya S, Xia TH, Liu X, Borza DB, Grafals M, Shankland SJ, Himmelfarb J, Portilla D, Liu S, Chau BN, Duffield JS
  (2015) J Clin Invest 125: 141-56
• Recessive osteogenesis imperfecta caused by missense mutations in SPARC.
  Mendoza-Londono R, Fahiminiya S, Majewski J, Care4Rare Canada Consortium, Tétreault M, Nadaf J, Kannu P, Sochett E, Howard A, Stimec J, Dupuis L, Roschger P, Klaushofer K, Palomo T, Ouellet J, Al-Jallad H, Mort JS, Moffatt P, Boudko S, Bächinger HP, Rauch F
  (2015) Am J Hum Genet 96: 979-85
• Serum endostatin is a genetically determined predictor of survival in pulmonary arterial hypertension.
  Damico R, Kolb TM, Valera L, Wang L, Housten T, Tedford RJ, Kass DA, Rafaels N, Gao L, Barnes KC, Benza RL, Rand JL, Hamid R, Loyd JE, Robbins IM, Hemnes AR, Chung WK, Austin ED, Drummond MB, Mathai SC, Hassoun PM
  (2015) Am J Respir Crit Care Med 191: 208-18
• Extracellular chloride signals collagen IV network assembly during basement membrane formation.
  Cummings CF, Pedchenko V, Brown KL, Colon S, Rafi M, Jones-Paris C, Pokydeshava E, Liu M, Pastor-Pareja JC, Stothers C, Ero-Tolliver IA, McCall AS, Vanacore R, Bhave G, Santoro S, Blackwell TS, Zent R, Pozzi A, Hudson BG
  (2016) J Cell Biol 213: 479-94
• PD-1 up-regulation on CD4 T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production.
  Celada LJ, Kropski JA, Herazo-Maya JD, Luo W, Creecy A, Abad AT, Chioma OS, Lee G, Hassell NE, Shaginurova GI, Wang Y, Johnson JE, Kerrigan A, Mason WR, Baughman RP, Ayers GD, Bernard GR, Culver DA, Montgomery CG, Maher TM, Molyneaux PL, Noth I, Mutsaers SE, Prele CM, Peebles RS, Newcomb DC, Kaminski N, Blackwell TS, Van Kaer L, Drake WP
  (2018) Sci Transl Med 10:
• Molecular targets for tumour progression in gastrointestinal stromal tumours.
  Koon N, Schneider-Stock R, Sarlomo-Rikala M, Lasota J, Smolkin M, Petroni G, Zaika A, Boltze C, Meyer F, Andersson L, Knuutila S, Miettinen M, El-Rifai W
  (2004) Gut 53: 235-40
• Collagen triple-helix formation in all-trans chains proceeds by a nucleation/growth mechanism with a purely entropic barrier.
  Bachmann A, Kiefhaber T, Boudko S, Engel J, Bächinger HP
  (2005) Proc Natl Acad Sci U S A 102: 13897-902
• A unique covalent bond in basement membrane is a primordial innovation for tissue evolution.
  Fidler AL, Vanacore RM, Chetyrkin SV, Pedchenko VK, Bhave G, Yin VP, Stothers CL, Rose KL, McDonald WH, Clark TA, Borza DB, Steele RE, Ivy MT, Aspirnauts, Hudson JK, Hudson BG
  (2014) Proc Natl Acad Sci U S A 111: 331-6
• Biological role of prolyl 3-hydroxylation in type IV collagen.
  Pokidysheva E, Boudko S, Vranka J, Zientek K, Maddox K, Moser M, Fässler R, Ware J, Bächinger HP
  (2014) Proc Natl Acad Sci U S A 111: 161-6
• Modification of collagen IV by glucose or methylglyoxal alters distinct mesangial cell functions.
  Pozzi A, Zent R, Chetyrkin S, Borza C, Bulus N, Chuang P, Chen D, Hudson B, Voziyan P
  (2009) J Am Soc Nephrol 20: 2119-25
• Quaternary epitopes of α345(IV) collagen initiate Alport post-transplant anti-GBM nephritis.
  Olaru F, Luo W, Wang XP, Ge L, Hertz JM, Kashtan CE, Sado Y, Segal Y, Hudson BG, Borza DB
  (2013) J Am Soc Nephrol 24: 889-95
• Distinct epitopes for anti-glomerular basement membrane alport alloantibodies and goodpasture autoantibodies within the noncollagenous domain of alpha3(IV) collagen: a janus-faced antigen.
  Wang XP, Fogo AB, Colon S, Giannico G, Abul-Ezz SR, Miner JH, Borza DB
  (2005) J Am Soc Nephrol 16: 3563-71
• Mannose receptor 2 attenuates renal fibrosis.
  López-Guisa JM, Cai X, Collins SJ, Yamaguchi I, Okamura DM, Bugge TH, Isacke CM, Emson CL, Turner SM, Shankland SJ, Eddy AA
  (2012) J Am Soc Nephrol 23: 236-51
• The Extracellular Matrix Receptor Discoidin Domain Receptor 1 Regulates Collagen Transcription by Translocating to the Nucleus.
  Chiusa M, Hu W, Liao HJ, Su Y, Borza CM, de Caestecker MP, Skrypnyk NI, Fogo AB, Pedchenko V, Li X, Zhang MZ, Hudson BG, Basak T, Vanacore RM, Zent R, Pozzi A
  (2019) J Am Soc Nephrol 30: 1605-1624
• Inhibitory Anti-Peroxidasin Antibodies in Pulmonary-Renal Syndromes.
  McCall AS, Bhave G, Pedchenko V, Hess J, Free M, Little DJ, Baker TP, Pendergraft WF, Falk RJ, Olson SW, Hudson BG
  (2018) J Am Soc Nephrol 29: 2619-2625
• Neonatal Fc receptor promotes immune complex-mediated glomerular disease.
  Olaru F, Luo W, Suleiman H, St John PL, Ge L, Mezo AR, Shaw AS, Abrahamson DR, Miner JH, Borza DB
  (2014) J Am Soc Nephrol 25: 918-25
• A nephritogenic peptide induces intermolecular epitope spreading on collagen IV in experimental autoimmune glomerulonephritis.
  Chen L, Hellmark T, Pedchenko V, Hudson BG, Pusey CD, Fox JW, Bolton WK
  (2006) J Am Soc Nephrol 17: 3076-81
• Antiangiogenic therapy in diabetic nephropathy.
  Zent R, Pozzi A
  (2006) J Am Soc Nephrol 17: 325-7
• Global analysis reveals the complexity of the human glomerular extracellular matrix.
  Lennon R, Byron A, Humphries JD, Randles MJ, Carisey A, Murphy S, Knight D, Brenchley PE, Zent R, Humphries MJ
  (2014) J Am Soc Nephrol 25: 939-51
• Imaging of podocyte foot processes by fluorescence microscopy.
  Grgic I, Brooks CR, Hofmeister AF, Bijol V, Bonventre JV, Humphreys BD
  (2012) J Am Soc Nephrol 23: 785-91
• Cellular origins of type IV collagen networks in developing glomeruli.
  Abrahamson DR, Hudson BG, Stroganova L, Borza DB, St John PL
  (2009) J Am Soc Nephrol 20: 1471-9
• Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice.
  Kang JS, Wang XP, Miner JH, Morello R, Sado Y, Abrahamson DR, Borza DB
  (2006) J Am Soc Nephrol 17: 1962-9
• The molecular basis of Goodpasture and Alport syndromes: beacons for the discovery of the collagen IV family.
  Hudson BG
  (2004) J Am Soc Nephrol 15: 2514-27
• The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN.
  Ooi JD, Chang J, O'Sullivan KM, Pedchenko V, Hudson BG, Vandenbark AA, Fugger L, Holdsworth SR, Kitching AR
  (2013) J Am Soc Nephrol 24: 419-31
• Human podocytes adhere to the KRGDS motif of the alpha3alpha4alpha5 collagen IV network.
  Borza CM, Borza DB, Pedchenko V, Saleem MA, Mathieson PW, Sado Y, Hudson HM, Pozzi A, Saus J, Abrahamson DR, Zent R, Hudson BG
  (2008) J Am Soc Nephrol 19: 677-84