APOL1 risk variants, race, and progression of chronic kidney disease. Parsa A, Kao WH, Xie D, Astor BC, Li M, Hsu CY, Feldman HI, Parekh RS, Kusek JW, Greene TH, Fink JC, Anderson AH, Choi MJ, Wright JT, Lash JP, Freedman BI, Ojo A, Winkler CA, Raj DS, Kopp JB, He J, Jensvold NG, Tao K, Lipkowitz MS, Appel LJ, AASK Study Investigators, CRIC Study Investigators (2013) N Engl J Med 369: 2183-96 Association between intensification of metformin treatment with insulin vs sulfonylureas and cardiovascular events and all-cause mortality among patients with diabetes. Roumie CL, Greevy RA, Grijalva CG, Hung AM, Liu X, Murff HJ, Elasy TA, Griffin MR (2014) JAMA 311: 2288-96 Role of sulfonylurea receptor type 1 subunits of ATP-sensitive potassium channels in myocardial ischemia/reperfusion injury. Elrod JW, Harrell M, Flagg TP, Gundewar S, Magnuson MA, Nichols CG, Coetzee WA, Lefer DJ (2008) Circulation 117: 1405-13 Single versus multiple internal mammary artery grafting for coronary artery bypass: 15-year follow-up of a clinical practice trial. Burfeind WR, Glower DD, Wechsler AS, Tuttle RH, Shaw LK, Harrell FE, Rankin JS (2004) Circulation 110: II27-35 Impact of obesity on plasma natriuretic peptide levels. Wang TJ, Larson MG, Levy D, Benjamin EJ, Leip EP, Wilson PW, Vasan RS (2004) Circulation 109: 594-600 High normal fasting blood glucose is associated with dementia in Chinese elderly. Mortimer JA, Borenstein AR, Ding D, Decarli C, Zhao Q, Copenhaver C, Guo Q, Chu S, Galasko D, Salmon DP, Dai Q, Wu Y, Petersen R, Hong Z (2010) Alzheimers Dement 6: 440-7 Statin use and risk of primary liver cancer in the Clinical Practice Research Datalink. McGlynn KA, Hagberg K, Chen J, Graubard BI, London WT, Jick S, Sahasrabuddhe VV (2015) J Natl Cancer Inst 107: Spoiling the whole bunch: quality control aimed at preserving the integrity of high-throughput genotyping. Pluzhnikov A, Below JE, Konkashbaev A, Tikhomirov A, Kistner-Griffin E, Roe CA, Nicolae DL, Cox NJ (2010) Am J Hum Genet 87: 123-8 A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. Paterson AD, Waggott D, Boright AP, Hosseini SM, Shen E, Sylvestre MP, Wong I, Bharaj B, Cleary PA, Lachin JM, MAGIC (Meta-Analyses of Glucose and Insulin-related traits Consortium), Below JE, Nicolae D, Cox NJ, Canty AJ, Sun L, Bull SB, Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group (2010) Diabetes 59: 539-49 Disease associations. Chance, artifact, or susceptibility genes? Cox NJ, Bell GI (1989) Diabetes 38: 947-50 Prevalence and prognostic impact of subclinical cardiovascular disease in individuals with the metabolic syndrome and diabetes. Ingelsson E, Sullivan LM, Murabito JM, Fox CS, Benjamin EJ, Polak JF, Meigs JB, Keyes MJ, O'Donnell CJ, Wang TJ, D'Agostino RB, Wolf PA, Vasan RS (2007) Diabetes 56: 1718-26 A Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk. Redondo MJ, Geyer S, Steck AK, Sharp S, Wentworth JM, Weedon MN, Antinozzi P, Sosenko J, Atkinson M, Pugliese A, Oram RA, Type 1 Diabetes TrialNet Study Group (2018) Diabetes Care 41: 1887-1894 Do impotent men with diabetes have more severe erectile dysfunction and worse quality of life than the general population of impotent patients? Results from the Exploratory Comprehensive Evaluation of Erectile Dysfunction (ExCEED) database. Penson DF, Latini DM, Lubeck DP, Wallace KL, Henning JM, Lue TF, Comprehensive Evaluation of Erectile Dysfunction (ExCEED) database (2003) Diabetes Care 26: 1093-9 Gestational Diabetes Mellitus Is Strongly Associated With Non-Alcoholic Fatty Liver Disease. Ajmera VH, Gunderson EP, VanWagner LB, Lewis CE, Carr JJ, Terrault NA (2016) Am J Gastroenterol 111: 658-64 Ethnic differences in the relationship between pericardial adipose tissue and coronary artery calcified plaque: African-American-diabetes heart study. Divers J, Wagenknecht LE, Bowden DW, Carr JJ, Hightower RC, Register TC, Xu J, Langefeld CD, Freedman BI (2010) J Clin Endocrinol Metab 95: 5382-9 Sclerostin is positively associated with bone mineral density in men and women and negatively associated with carotid calcified atherosclerotic plaque in men from the African American-Diabetes Heart Study. Register TC, Hruska KA, Divers J, Bowden DW, Palmer ND, Carr JJ, Wagenknecht LE, Hightower RC, Xu J, Smith SC, Dietzen DJ, Langefeld CD, Freedman BI (2014) J Clin Endocrinol Metab 99: 315-21 Biomolecular signatures of diabetic wound healing by structural mass spectrometry. Hines KM, Ashfaq S, Davidson JM, Opalenik SR, Wikswo JP, McLean JA (2013) Anal Chem 85: 3651-9 Pyridoxamine as a multifunctional pharmaceutical: targeting pathogenic glycation and oxidative damage. Voziyan PA, Hudson BG (2005) Cell Mol Life Sci 62: 1671-81 Agreement of self-reported comorbid conditions with medical and physician reports varied by disease among end-stage renal disease patients. Merkin SS, Cavanaugh K, Longenecker JC, Fink NE, Levey AS, Powe NR (2007) J Clin Epidemiol 60: 634-42 Quality of life during and between hemodialysis treatments: role of L-carnitine supplementation. Sloan RS, Kastan B, Rice SI, Sallee CW, Yuenger NJ, Smith B, Ward RA, Brier ME, Golper TA (1998) Am J Kidney Dis 32: 265-72 Fenoldopam mesylate in early acute tubular necrosis: a randomized, double-blind, placebo-controlled clinical trial. Tumlin JA, Finkel KW, Murray PT, Samuels J, Cotsonis G, Shaw AD (2005) Am J Kidney Dis 46: 26-34 Microalbuminuria as a target to improve cardiovascular and renal outcomes. Basi S, Lewis JB (2006) Am J Kidney Dis 47: 927-46 Diabetes mellitus and prostate cancer risk among older men: population-based case-control study. Coker AL, Sanderson M, Zheng W, Fadden MK (2004) Br J Cancer 90: 2171-5 Estimating the likelihood of significant coronary artery disease. Pryor DB, Harrell FE, Lee KL, Califf RM, Rosati RA (1983) Am J Med 75: 771-80 K-ras and p53 in pancreatic cancer: association with medical history, histopathology, and environmental exposures in a population-based study. Slebos RJ, Hoppin JA, Tolbert PE, Holly EA, Brock JW, Zhang RH, Bracci PM, Foley J, Stockton P, McGregor LM, Flake GP, Taylor JA (2000) Cancer Epidemiol Biomarkers Prev 9: 1223-32 Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry. Hou N, Zheng Y, Gamazon ER, Ogundiran TO, Adebamowo C, Nathanson KL, Domchek SM, Rebbeck TR, Simon MS, John EM, Hennis A, Nemesure B, Wu SY, Leske MC, Ambs S, Niu Q, Zhang J, Pierce B, Cox NJ, Olopade OI, Huo D (2012) Cancer Epidemiol Biomarkers Prev 21: 552-6 The relationship between C-reactive protein and subclinical cardiovascular disease in the Diabetes Heart Study (DHS). Bowden DW, Lange LA, Langefeld CD, Brosnihan KB, Freedman BI, Carr JJ, Wagenknecht LE, Herrington DM (2005) Am Heart J 150: 1032-8 Targeting cardiovascular risk in patients with diabetes: management of dyslipidemia. Ali YS, Linton MF, Fazio S (2008) Curr Opin Endocrinol Diabetes Obes 15: 142-6 Variants in adiponectin signaling pathway genes show little association with subclinical CVD in the diabetes heart study. Cox AJ, Lambird JE, An SS, Register TC, Langefeld CD, Carr JJ, Freedman BI, Bowden DW (2013) Obesity (Silver Spring) 21: E456-62 Screening asymptomatic diabetic patients for coronary artery disease prior to renal transplantation. Ramanathan V, Goral S, Tanriover B, Feurer ID, Kazancioglu R, Shaffer D, Helderman JH (2005) Transplantation 79: 1453-8 Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study. Cox AJ, Ng MC, Xu J, Langefeld CD, Koch KL, Dawson PA, Carr JJ, Freedman BI, Hsu FC, Bowden DW (2013) Atherosclerosis 229: 155-60 Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study. Rudock ME, Liu Y, Ziegler JT, Allen SG, Lehtinen AB, Freedman BI, Carr JJ, Langefeld CD, Bowden DW (2009) Atherosclerosis 203: 459-65 Systemic diseases associated with nonarteritic anterior ischemic optic neuropathy. Hayreh SS, Joos KM, Podhajsky PA, Long CR (1994) Am J Ophthalmol 118: 766-80 Sexual dysfunction and symptom impact in men with long-standing type 1 diabetes in the DCCT/EDIC cohort. Penson DF, Wessells H, Cleary P, Rutledge BN, Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group (2009) J Sex Med 6: 1969-78 Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans. Cooke JN, Bostrom MA, Hicks PJ, Ng MC, Hellwege JN, Comeau ME, Divers J, Langefeld CD, Freedman BI, Bowden DW (2012) Nephrol Dial Transplant 27: 1505-11 Microalbuminuria as a target to improve cardiovascular and renal outcomes in diabetic patients. Basi S, Lewis JB (2007) Curr Diab Rep 7: 439-42 Diabetes mellitus, other medical conditions and pancreatic cancer: a case-control study. Lipworth L, Zucchetto A, Bosetti C, Franceschi S, Talamini R, Serraino D, McLaughlin JK, La Vecchia C, Negri E (2011) Diabetes Metab Res Rev 27: 255-61 End-stage renal disease. Parker T, Hakim R, Ismail N (1997) Semin Nephrol 17: 253-6 Association between prostate-specific antigen and leptin, adiponectin, HbA1c or C-peptide among African-American and Caucasian men. Fowke JH, Matthews CM, Buchowski MS, Signorello LB, Chang SS, Cookson MS, Blot WJ (2008) Prostate Cancer Prostatic Dis 11: 264-9 Effects of diabetes and cadaveric organs on functional performance and health-related quality of life after kidney transplantation. Kizilisik AT, Feurer ID, VanBuren DH, Wise P, Van Buren D, Hopkins J, Ray J, Nylander W, Shaffer D, Helderman JH, Langone AJ, Speroff T, Pinson CW (2003) Am J Surg 186: 535-9
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