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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Myocytes, Smooth Muscle are shown below. Double-click or tap a node for more information.
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- Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery disease.
Guzik TJ, Chen W, Gongora MC, Guzik B, Lob HE, Mangalat D, Hoch N, Dikalov S, Rudzinski P, Kapelak B, Sadowski J, Harrison DG
(2008) J Am Coll Cardiol 52: 1803-9 - Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension.
Bertero T, Oldham WM, Cottrill KA, Pisano S, Vanderpool RR, Yu Q, Zhao J, Tai Y, Tang Y, Zhang YY, Rehman S, Sugahara M, Qi Z, Gorcsan J, Vargas SO, Saggar R, Saggar R, Wallace WD, Ross DJ, Haley KJ, Waxman AB, Parikh VN, De Marco T, Hsue PY, Morris A, Simon MA, Norris KA, Gaggioli C, Loscalzo J, Fessel J, Chan SY
(2016) J Clin Invest 126: 3313-35 - Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration.
Majka SM, Jackson KA, Kienstra KA, Majesky MW, Goodell MA, Hirschi KK
(2003) J Clin Invest 111: 71-9 - Retinal angiogenesis suppression through small molecule activation of p53.
Chavala SH, Kim Y, Tudisco L, Cicatiello V, Milde T, Kerur N, Claros N, Yanni S, Guaiquil VH, Hauswirth WW, Penn JS, Rafii S, De Falco S, Lee TC, Ambati J
(2013) J Clin Invest 123: 4170-81 - Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury.
Volckaert T, Dill E, Campbell A, Tiozzo C, Majka S, Bellusci S, De Langhe SP
(2011) J Clin Invest 121: 4409-19 - 5' CArG degeneracy in smooth muscle alpha-actin is required for injury-induced gene suppression in vivo.
Hendrix JA, Wamhoff BR, McDonald OG, Sinha S, Yoshida T, Owens GK
(2005) J Clin Invest 115: 418-27 - A G/C element mediates repression of the SM22alpha promoter within phenotypically modulated smooth muscle cells in experimental atherosclerosis.
Wamhoff BR, Hoofnagle MH, Burns A, Sinha S, McDonald OG, Owens GK
(2004) Circ Res 95: 981-8 - Programming smooth muscle plasticity with chromatin dynamics.
McDonald OG, Owens GK
(2007) Circ Res 100: 1428-41 - L-type voltage-gated Ca2+ channels modulate expression of smooth muscle differentiation marker genes via a rho kinase/myocardin/SRF-dependent mechanism.
Wamhoff BR, Bowles DK, McDonald OG, Sinha S, Somlyo AP, Somlyo AV, Owens GK
(2004) Circ Res 95: 406-14 - Wnt10b Gain-of-Function Improves Cardiac Repair by Arteriole Formation and Attenuation of Fibrosis.
Paik DT, Rai M, Ryzhov S, Sanders LN, Aisagbonhi O, Funke MJ, Feoktistov I, Hatzopoulos AK
(2015) Circ Res 117: 804-16 - Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension.
Aldred MA, Comhair SA, Varella-Garcia M, Asosingh K, Xu W, Noon GP, Thistlethwaite PA, Tuder RM, Erzurum SC, Geraci MW, Coldren CD
(2010) Am J Respir Crit Care Med 182: 1153-60 - Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin.
Bix G, Fu J, Gonzalez EM, Macro L, Barker A, Campbell S, Zutter MM, Santoro SA, Kim JK, Höök M, Reed CC, Iozzo RV
(2004) J Cell Biol 166: 97-109 - MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia.
Evans BC, Hocking KM, Osgood MJ, Voskresensky I, Dmowska J, Kilchrist KV, Brophy CM, Duvall CL
(2015) Sci Transl Med 7: 291ra95 - Hepatocyte growth factor mediates angiopoietin-induced smooth muscle cell recruitment.
Kobayashi H, DeBusk LM, Babichev YO, Dumont DJ, Lin PC
(2006) Blood 108: 1260-6 - Low nitric oxide bioavailability upregulates renal heparin binding EGF-like growth factor expression.
Miyazawa T, Zeng F, Wang S, Fan X, Cheng H, Yang H, Bian A, Fogo AB, Harris RC
(2013) Kidney Int 84: 1176-88 - Heparin-functionalized polymer graft surface eluting MK2 inhibitory peptide to improve hemocompatibility and anti-neointimal activity.
Lee Y, Le Thi P, Seon GM, Ryu SB, Brophy CM, Kim Y, Park JC, Park KD, Cheung-Flynn J, Sung HJ
(2017) J Control Release 266: 321-330 - A differential role for endocytosis in receptor-mediated activation of Nox1.
Miller FJ, Chu X, Stanic B, Tian X, Sharma RV, Davisson RL, Lamb FS
(2010) Antioxid Redox Signal 12: 583-93 - Functional regulation of ClC-3 in the migration of vascular smooth muscle cells.
Ganapathi SB, Wei SG, Zaremba A, Lamb FS, Shears SB
(2013) Hypertension 61: 174-9 - Hypoxia modulates adenosine receptors in human endothelial and smooth muscle cells toward an A2B angiogenic phenotype.
Feoktistov I, Ryzhov S, Zhong H, Goldstein AE, Matafonov A, Zeng D, Biaggioni I
(2004) Hypertension 44: 649-54 - Identification of small proline-rich repeat protein 3 as a novel atheroprotective factor that promotes adaptive Akt signaling in vascular smooth muscle cells.
Segedy AK, Pyle AL, Li B, Zhang Y, Babaev VR, Jat P, Fazio S, Atkinson JB, Linton MF, Young PP
(2014) Arterioscler Thromb Vasc Biol 34: 2527-36 - Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading.
Tian H, Ketova T, Hardy D, Xu X, Gao X, Zijlstra A, Blobe GC
(2017) Arterioscler Thromb Vasc Biol 37: 1115-1126 - ACAT inhibition: bad for macrophages, good for smooth muscle cells?
Fazio S, Dove DE, Linton MF
(2005) Arterioscler Thromb Vasc Biol 25: 7-9 - The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature.
Wilm B, Ipenberg A, Hastie ND, Burch JB, Bader DM
(2005) Development 132: 5317-28 - SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation.
Ai X, Kitazawa T, Do AT, Kusche-Gullberg M, Labosky PA, Emerson CP
(2007) Development 134: 3327-38 - Podosome formation in cultured A7r5 vascular smooth muscle cells requires Arp2/3-dependent de-novo actin polymerization at discrete microdomains.
Kaverina I, Stradal TE, Gimona M
(2003) J Cell Sci 116: 4915-24 - PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells.
Davis CA, Haberland M, Arnold MA, Sutherland LB, McDonald OG, Richardson JA, Childs G, Harris S, Owens GK, Olson EN
(2006) Mol Cell Biol 26: 2626-36 - LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis.
Choi H, Ettinger N, Rohrbough J, Dikalova A, Nguyen HN, Lamb FS
(2016) Free Radic Biol Med 101: 413-423 - Functional association of nox1 with p22phox in vascular smooth muscle cells.
Hanna IR, Hilenski LL, Dikalova A, Taniyama Y, Dikalov S, Lyle A, Quinn MT, Lassègue B, Griendling KK
(2004) Free Radic Biol Med 37: 1542-9 - c-Jun N-terminal kinase attenuates TNFα signaling by reducing Nox1-dependent endosomal ROS production in vascular smooth muscle cells.
Choi H, Dikalova A, Stark RJ, Lamb FS
(2015) Free Radic Biol Med 86: 219-27 - Modular polymer design to regulate phenotype and oxidative response of human coronary artery cells for potential stent coating applications.
Crowder SW, Gupta MK, Hofmeister LH, Zachman AL, Sung HJ
(2012) Acta Biomater 8: 559-69 - Nephrogenic fibrosing dermopathy: a novel cutaneous fibrosing disorder in patients with renal failure.
Swartz RD, Crofford LJ, Phan SH, Ike RW, Su LD
(2003) Am J Med 114: 563-72 - Early endosomal antigen 1 (EEA1) is an obligate scaffold for angiotensin II-induced, PKC-alpha-dependent Akt activation in endosomes.
Nazarewicz RR, Salazar G, Patrushev N, San Martin A, Hilenski L, Xiong S, Alexander RW
(2011) J Biol Chem 286: 2886-95 - Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
Miller M, Shi J, Zhu Y, Kustov M, Tian JB, Stevens A, Wu M, Xu J, Long S, Yang P, Zholos AV, Salovich JM, Weaver CD, Hopkins CR, Lindsley CW, McManus O, Li M, Zhu MX
(2011) J Biol Chem 286: 33436-46 - Somatic cell plasticity and Niemann-Pick type C2 protein: fibroblast activation.
Csepeggi C, Jiang M, Kojima F, Crofford LJ, Frolov A
(2011) J Biol Chem 286: 2078-87 - Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease.
Lewis TL, Cao D, Lu H, Mans RA, Su YR, Jungbauer L, Linton MF, Fazio S, LaDu MJ, Li L
(2010) J Biol Chem 285: 36958-68 - Calponin repeats regulate actin filament stability and formation of podosomes in smooth muscle cells.
Gimona M, Kaverina I, Resch GP, Vignal E, Burgstaller G
(2003) Mol Biol Cell 14: 2482-91 - Atheromas feel the pressure: biomechanical stress and atherosclerosis.
Pyle AL, Young PP
(2010) Am J Pathol 177: 4-9 - Regulation of the atheroma-enriched protein, SPRR3, in vascular smooth muscle cells through cyclic strain is dependent on integrin alpha1beta1/collagen interaction.
Pyle AL, Atkinson JB, Pozzi A, Reese J, Eckes B, Davidson JM, Crimmins DL, Young PP
(2008) Am J Pathol 173: 1577-88 - Comparative analysis of myometrial and vascular smooth muscle cells to determine optimal cells for use in drug discovery.
Siricilla S, Knapp KM, Rogers JH, Berger C, Shelton EL, Mi D, Vinson P, Condon J, Paria BC, Reese J, Sheng Q, Herington JL
(2019) Pharmacol Res 146: 104268 - Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species.
Samarakoon R, Dobberfuhl AD, Cooley C, Overstreet JM, Patel S, Goldschmeding R, Meldrum KK, Higgins PJ
(2013) Cell Signal 25: 2198-209
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