CXCL1 induced by prostaglandin E2 promotes angiogenesis in colorectal cancer. Wang D, Wang H, Brown J, Daikoku T, Ning W, Shi Q, Richmond A, Strieter R, Dey SK, DuBois RN (2006) J Exp Med 203: 941-51 Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma. Ijichi H, Chytil A, Gorska AE, Aakre ME, Bierie B, Tada M, Mohri D, Miyabayashi K, Asaoka Y, Maeda S, Ikenoue T, Tateishi K, Wright CV, Koike K, Omata M, Moses HL (2011) J Clin Invest 121: 4106-17 TGF-β receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms. Novitskiy SV, Pickup MW, Gorska AE, Owens P, Chytil A, Aakre M, Wu H, Shyr Y, Moses HL (2011) Cancer Discov 1: 430-41 Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thromboglobulin. Richmond A, Balentien E, Thomas HG, Flaggs G, Barton DE, Spiess J, Bordoni R, Francke U, Derynck R (1988) EMBO J 7: 2025-33 Elevated constitutive IkappaB kinase activity and IkappaB-alpha phosphorylation in Hs294T melanoma cells lead to increased basal MGSA/GRO-alpha transcription. Devalaraja MN, Wang DZ, Ballard DW, Richmond A (1999) Cancer Res 59: 1372-7 Constitutive IkappaB kinase activity correlates with nuclear factor-kappaB activation in human melanoma cells. Yang J, Richmond A (2001) Cancer Res 61: 4901-9 Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium. Ao M, Franco OE, Park D, Raman D, Williams K, Hayward SW (2007) Cancer Res 67: 4244-53 HMGI(Y) and Sp1 in addition to NF-kappa B regulate transcription of the MGSA/GRO alpha gene. Wood LD, Farmer AA, Richmond A (1995) Nucleic Acids Res 23: 4210-9 Nucleotide sequence of the human melanoma growth stimulatory activity (MGSA) gene. Baker NE, Kucera G, Richmond A (1990) Nucleic Acids Res 18: 6453 Mob-1, a Ras target gene, is overexpressed in colorectal cancer. Zhang R, Zhang H, Zhu W, Pardee AB, Coffey RJ, Liang P (1997) Oncogene 14: 1607-10 Differential regulation of CXC ligand 1 transcription in melanoma cell lines by poly(ADP-ribose) polymerase-1. Amiri KI, Ha HC, Smulson ME, Richmond A (2006) Oncogene 25: 7714-22 Effects of MGSA/GRO alpha on melanocyte transformation. Balentien E, Mufson BE, Shattuck RL, Derynck R, Richmond A (1991) Oncogene 6: 1115-24 MGSA/GRO-mediated melanocyte transformation involves induction of Ras expression. Wang D, Yang W, Du J, Devalaraja MN, Liang P, Matsumoto K, Tsubakimoto K, Endo T, Richmond A (2000) Oncogene 19: 4647-59 The angiostatic activity of interferon-inducible protein-10/CXCL10 in human melanoma depends on binding to CXCR3 but not to glycosaminoglycan. Yang J, Richmond A (2004) Mol Ther 9: 846-55 Signals from both sides: Control of cardiac development by the endocardium and epicardium. Smith TK, Bader DM (2007) Semin Cell Dev Biol 18: 84-9 Enhanced tumor-forming capacity for immortalized melanocytes expressing melanoma growth stimulatory activity/growth-regulated cytokine beta and gamma proteins. Owen JD, Strieter R, Burdick M, Haghnegahdar H, Nanney L, Shattuck-Brandt R, Richmond A (1997) Int J Cancer 73: 94-103 The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity. Addison CL, Daniel TO, Burdick MD, Liu H, Ehlert JE, Xue YY, Buechi L, Walz A, Richmond A, Strieter RM (2000) J Immunol 165: 5269-77 The melanoma growth stimulatory activity receptor consists of two proteins. Ligand binding results in enhanced tyrosine phosphorylation. Cheng QC, Han JH, Thomas HG, Balentien E, Richmond A (1992) J Immunol 148: 451-6 TNF influences chemokine expression of macrophages in vitro and that of CD11b+ cells in vivo during Mycobacterium tuberculosis infection. Algood HM, Lin PL, Yankura D, Jones A, Chan J, Flynn JL (2004) J Immunol 172: 6846-57 In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation. Blackwell TS, Blackwell TR, Holden EP, Christman BW, Christman JW (1996) J Immunol 157: 1630-7 Downregulation of JE and KC genes by glucocorticoids does not prevent the G0----G1 transition in BALB/3T3 cells. Rameh LE, Armelin MC (1992) Mol Cell Biol 12: 4612-21 MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells. Shattuck RL, Wood LD, Jaffe GJ, Richmond A (1994) Mol Cell Biol 14: 791-802 Activation of protein kinase C enhances the phosphorylation of the type B interleukin-8 receptor and stimulates its degradation in non-hematopoietic cells. Mueller SG, Schraw WP, Richmond A (1995) J Biol Chem 270: 10439-48 Melanoma growth stimulatory activity enhances the phosphorylation of the class II interleukin-8 receptor in non-hematopoietic cells. Mueller SG, Schraw WP, Richmond A (1994) J Biol Chem 269: 1973-80 Ligand-induced desensitization of the human CXC chemokine receptor-2 is modulated by multiple serine residues in the carboxyl-terminal domain of the receptor. Mueller SG, White JR, Schraw WP, Lam V, Richmond A (1997) J Biol Chem 272: 8207-14 Role of clathrin-mediated endocytosis in CXCR2 sequestration, resensitization, and signal transduction. Yang W, Wang D, Richmond A (1999) J Biol Chem 274: 11328-33 A role for poly(ADP-ribose) polymerase in the transcriptional regulation of the melanoma growth stimulatory activity (CXCL1) gene expression. Nirodi C, NagDas S, Gygi SP, Olson G, Aebersold R, Richmond A (2001) J Biol Chem 276: 9366-74 Nuclear factor-kappa B activation by the CXC chemokine melanoma growth-stimulatory activity/growth-regulated protein involves the MEKK1/p38 mitogen-activated protein kinase pathway. Wang D, Richmond A (2001) J Biol Chem 276: 3650-9 Constitutive and cytokine-induced expression of the melanoma growth stimulatory activity/GRO alpha gene requires both NF-kappa B and novel constitutive factors. Wood LD, Richmond A (1995) J Biol Chem 270: 30619-26 Rab11-family interacting protein 2 and myosin Vb are required for CXCR2 recycling and receptor-mediated chemotaxis. Fan GH, Lapierre LA, Goldenring JR, Sai J, Richmond A (2004) Mol Biol Cell 15: 2456-69 The tumorigenic and angiogenic effects of MGSA/GRO proteins in melanoma. Haghnegahdar H, Du J, Wang D, Strieter RM, Burdick MD, Nanney LB, Cardwell N, Luan J, Shattuck-Brandt R, Richmond A (2000) J Leukoc Biol 67: 53-62 Role of CXCL1 in tumorigenesis of melanoma. Dhawan P, Richmond A (2002) J Leukoc Biol 72: 9-18 Mechanism and biological significance of constitutive expression of MGSA/GRO chemokines in malignant melanoma tumor progression. Luan J, Shattuck-Brandt R, Haghnegahdar H, Owen JD, Strieter R, Burdick M, Nirodi C, Beauchamp D, Johnson KN, Richmond A (1997) J Leukoc Biol 62: 588-97 Potential role for Duffy antigen chemokine-binding protein in angiogenesis and maintenance of homeostasis in response to stress. Du J, Luan J, Liu H, Daniel TO, Peiper S, Chen TS, Yu Y, Horton LW, Nanney LB, Strieter RM, Richmond A (2002) J Leukoc Biol 71: 141-53 Distributions of melanoma growth stimulatory activity of growth-regulated gene and the interleukin-8 receptor B in human wound repair. Nanney LB, Mueller SG, Bueno R, Peiper SC, Richmond A (1995) Am J Pathol 147: 1248-60 A 588-gene microarray analysis of the peripheral blood mononuclear cells of spondyloarthropathy patients. Gu J, Märker-Hermann E, Baeten D, Tsai WC, Gladman D, Xiong M, Deister H, Kuipers JG, Huang F, Song YW, Maksymowych W, Kalsi J, Bannai M, Seta N, Rihl M, Crofford LJ, Veys E, De Keyser F, Yu DT (2002) Rheumatology (Oxford) 41: 759-66 Role of granulocyte macrophage colony-stimulating factor during gram-negative lung infection with Pseudomonas aeruginosa. Ballinger MN, Paine R, Serezani CH, Aronoff DM, Choi ES, Standiford TJ, Toews GB, Moore BB (2006) Am J Respir Cell Mol Biol 34: 766-74 Inhibition of pulmonary fibrosis by the chemokine IP-10/CXCL10. Tager AM, Kradin RL, LaCamera P, Bercury SD, Campanella GS, Leary CP, Polosukhin V, Zhao LH, Sakamoto H, Blackwell TS, Luster AD (2004) Am J Respir Cell Mol Biol 31: 395-404 Cytokine-induced neutrophil chemoattractant mediates neutrophilic alveolitis in rats: association with nuclear factor kappa B activation. Blackwell TS, Holden EP, Blackwell TR, DeLarco JE, Christman JW (1994) Am J Respir Cell Mol Biol 11: 464-72 Impaired pulmonary NF-kappaB activation in response to lipopolysaccharide in NADPH oxidase-deficient mice. Koay MA, Christman JW, Segal BH, Venkatakrishnan A, Blackwell TR, Holland SM, Blackwell TS (2001) Infect Immun 69: 5991-6
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