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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Blood Proteins are shown below. Double-click or tap a node for more information.
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Publications
- Increased expression of an adhesion-promoting surface glycoprotein in the granulocytopenia of hemodialysis.
Arnaout MA, Hakim RM, Todd RF, Dana N, Colten HR
(1985) N Engl J Med 312: 457-62 - Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.
Harlan JE, Hajduk PJ, Yoon HS, Fesik SW
(1994) Nature 371: 168-70 - Solution structure of a pleckstrin-homology domain.
Yoon HS, Hajduk PJ, Petros AM, Olejniczak ET, Meadows RP, Fesik SW
(1994) Nature 369: 672-5 - A stomatin-like protein necessary for mechanosensation in C. elegans.
Huang M, Gu G, Ferguson EL, Chalfie M
(1995) Nature 378: 292-5 - Structure and ligand recognition of the phosphotyrosine binding domain of Shc.
Zhou MM, Ravichandran KS, Olejniczak EF, Petros AM, Meadows RP, Sattler M, Harlan JE, Wade WS, Burakoff SJ, Fesik SW
(1995) Nature 378: 584-92 - Integrin-linked kinase is an adaptor with essential functions during mouse development.
Lange A, Wickström SA, Jakobson M, Zent R, Sainio K, Fässler R
(2009) Nature 461: 1002-6 - Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma.
Addona TA, Abbatiello SE, Schilling B, Skates SJ, Mani DR, Bunk DM, Spiegelman CH, Zimmerman LJ, Ham AJ, Keshishian H, Hall SC, Allen S, Blackman RK, Borchers CH, Buck C, Cardasis HL, Cusack MP, Dodder NG, Gibson BW, Held JM, Hiltke T, Jackson A, Johansen EB, Kinsinger CR, Li J, Mesri M, Neubert TA, Niles RK, Pulsipher TC, Ransohoff D, Rodriguez H, Rudnick PA, Smith D, Tabb DL, Tegeler TJ, Variyath AM, Vega-Montoto LJ, Wahlander A, Waldemarson S, Wang M, Whiteaker JR, Zhao L, Anderson NL, Fisher SJ, Liebler DC, Paulovich AG, Regnier FE, Tempst P, Carr SA
(2009) Nat Biotechnol 27: 633-41 - Phosphoinositide binding domains: embracing 3-phosphate.
Fruman DA, Rameh LE, Cantley LC
(1999) Cell 97: 817-20 - A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor.
Trofatter JA, MacCollin MM, Rutter JL, Murrell JR, Duyao MP, Parry DM, Eldridge R, Kley N, Menon AG, Pulaski K
(1993) Cell 72: 791-800 - NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio.
Liu X, Wang H, Eberstadt M, Schnuchel A, Olejniczak ET, Meadows RP, Schkeryantz JM, Janowick DA, Harlan JE, Harris EA, Staunton DE, Fesik SW
(1998) Cell 95: 269-77 - Competition for related but nonidentical binding sites on the glycoprotein IIb-IIIa complex by peptides derived from platelet adhesive proteins.
Santoro SA, Lawing WJ
(1987) Cell 48: 867-73 - Mapping the proteo-genomic convergence of human diseases.
Pietzner M, Wheeler E, Carrasco-Zanini J, Cortes A, Koprulu M, Wörheide MA, Oerton E, Cook J, Stewart ID, Kerrison ND, Luan J, Raffler J, Arnold M, Arlt W, O'Rahilly S, Kastenmüller G, Gamazon ER, Hingorani AD, Scott RA, Wareham NJ, Langenberg C
(2021) Science 374: eabj1541 - Multiple biomarkers and risk of clinical and subclinical vascular brain injury: the Framingham Offspring Study.
Pikula A, Beiser AS, DeCarli C, Himali JJ, Debette S, Au R, Selhub J, Toffler GH, Wang TJ, Meigs JB, Kelly-Hayes M, Kase CS, Wolf PA, Vasan RS, Seshadri S
(2012) Circulation 125: 2100-7 - Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines.
Adachi Y, Lee CT, Coffee K, Yamagata N, Ohm JE, Park KH, Dikov MM, Nadaf SR, Arteaga CL, Carbone DP
(2002) Gastroenterology 123: 1191-204 - Modulation of human platelet protein kinase C by endotoxic lipid A.
Grabarek J, Timmons S, Hawiger J
(1988) J Clin Invest 82: 964-71 - Increased protein nitration burden in the atherosclerotic lesions and plasma of apolipoprotein A-I deficient mice.
Parastatidis I, Thomson L, Fries DM, Moore RE, Tohyama J, Fu X, Hazen SL, Heijnen HF, Dennehy MK, Liebler DC, Rader DJ, Ischiropoulos H
(2007) Circ Res 101: 368-76 - Inhaled nitric oxide reduces lung fluid filtration after endotoxin in awake sheep.
Bjertnaes LJ, Koizumi T, Newman JH
(1998) Am J Respir Crit Care Med 158: 1416-23 - Fibronectin and the multiple interaction model for platelet-collagen adhesion.
Santoro SA, Cunningham LW
(1979) Proc Natl Acad Sci U S A 76: 2644-8 - Membrane-bound myo1c powers asymmetric motility of actin filaments.
Pyrpassopoulos S, Feeser EA, Mazerik JN, Tyska MJ, Ostap EM
(2012) Curr Biol 22: 1688-92 - Oxidative stress is increased in critically ill patients with acute renal failure.
Himmelfarb J, McMonagle E, Freedman S, Klenzak J, McMenamin E, Le P, Pupim LB, Ikizler TA, The PICARD Group
(2004) J Am Soc Nephrol 15: 2449-56 - Gentamicin and phenytoin sieving through hollow-fiber polysulfone hemofilters.
Golper TA, Saad AM
(1986) Kidney Int 30: 937-43 - Influence of initiation of maintenance hemodialysis on biomarkers of inflammation and oxidative stress.
Pupim LB, Himmelfarb J, McMonagle E, Shyr Y, Ikizler TA
(2004) Kidney Int 65: 2371-9 - Localization of clusterin in the epimembranous deposits of passive Heymann nephritis.
Eddy AA, Fritz IB
(1991) Kidney Int 39: 247-52 - Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis.
Yang HC, Ma LJ, Ma J, Fogo AB
(2006) Kidney Int 69: 1756-64 - Proteinase activity in human and murine saliva as a biomarker for proteinase inhibitor efficacy.
Fingleton B, Menon R, Carter KJ, Overstreet PD, Hachey DL, Matrisian LM, McIntyre JO
(2004) Clin Cancer Res 10: 7865-74 - Evidence for eosinophil activation in cancer patients receiving recombinant interleukin-4: effects of interleukin-4 alone and following interleukin-2 administration.
Sosman JA, Bartemes K, Offord KP, Kita H, Fisher SG, Kefer C, Ellis TA, Fisher RI, Higgins TJ, Gleich GJ
(1995) Clin Cancer Res 1: 805-12 - Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
Wen W, Zheng W, Okada Y, Takeuchi F, Tabara Y, Hwang JY, Dorajoo R, Li H, Tsai FJ, Yang X, He J, Wu Y, He M, Zhang Y, Liang J, Guo X, Sheu WH, Delahanty R, Guo X, Kubo M, Yamamoto K, Ohkubo T, Go MJ, Liu JJ, Gan W, Chen CC, Gao Y, Li S, Lee NR, Wu C, Zhou X, Song H, Yao J, Lee IT, Long J, Tsunoda T, Akiyama K, Takashima N, Cho YS, Ong RT, Lu L, Chen CH, Tan A, Rice TK, Adair LS, Gui L, Allison M, Lee WJ, Cai Q, Isomura M, Umemura S, Kim YJ, Seielstad M, Hixson J, Xiang YB, Isono M, Kim BJ, Sim X, Lu W, Nabika T, Lee J, Lim WY, Gao YT, Takayanagi R, Kang DH, Wong TY, Hsiung CA, Wu IC, Juang JM, Shi J, Choi BY, Aung T, Hu F, Kim MK, Lim WY, Wang TD, Shin MH, Lee J, Ji BT, Lee YH, Young TL, Shin DH, Chun BY, Cho MC, Han BG, Hwu CM, Assimes TL, Absher D, Yan X, Kim E, Kuo JZ, Kwon S, Taylor KD, Chen YD, Rotter JI, Qi L, Zhu D, Wu T, Mohlke KL, Gu D, Mo Z, Wu JY, Lin X, Miki T, Tai ES, Lee JY, Kato N, Shu XO, Tanaka T
(2014) Hum Mol Genet 23: 5492-504 - An azido-biotin reagent for use in the isolation of protein adducts of lipid-derived electrophiles by streptavidin catch and photorelease.
Kim HY, Tallman KA, Liebler DC, Porter NA
(2009) Mol Cell Proteomics 8: 2080-9 - Global stability of plasma proteomes for mass spectrometry-based analyses.
Zimmerman LJ, Li M, Yarbrough WG, Slebos RJ, Liebler DC
(2012) Mol Cell Proteomics 11: M111.014340 - Identification of a monogenic locus (jams1) causing juvenile audiogenic seizures in mice.
Misawa H, Sherr EH, Lee DJ, Chetkovich DM, Tan A, Schreiner CE, Bredt DS
(2002) J Neurosci 22: 10088-93 - Association of alpha2-Heremans-Schmid glycoprotein polymorphisms with subclinical atherosclerosis.
Lehtinen AB, Burdon KP, Lewis JP, Langefeld CD, Ziegler JT, Rich SS, Register TC, Carr JJ, Freedman BI, Bowden DW
(2007) J Clin Endocrinol Metab 92: 345-52 - Determining the aetiology of pulmonary oedema by the oedema fluid-to-plasma protein ratio.
Ware LB, Fremont RD, Bastarache JA, Calfee CS, Matthay MA
(2010) Eur Respir J 35: 331-7 - Albumin and furosemide therapy in hypoproteinemic patients with acute lung injury.
Martin GS, Mangialardi RJ, Wheeler AP, Dupont WD, Morris JA, Bernard GR
(2002) Crit Care Med 30: 2175-82 - Hypoproteinemia predicts acute respiratory distress syndrome development, weight gain, and death in patients with sepsis. Ibuprofen in Sepsis Study Group.
Mangialardi RJ, Martin GS, Bernard GR, Wheeler AP, Christman BW, Dupont WD, Higgins SB, Swindell BB
(2000) Crit Care Med 28: 3137-45 - Interaction of Histoplasma capsulatum with human platelets.
Des Prez RM, Steckley S, Stroud RM, Hawiger J
(1980) J Infect Dis 142: 32-9 - Parallel electrophoretic depletion, fractionation, concentration, and desalting of 96 complex biological samples for mass spectrometry.
Harkins JB, Katz BB, Pastor SJ, Osucha P, Hafeman DG, Witkowski CE, Norris JL
(2008) Anal Chem 80: 2734-43 - Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor.
Lavieri RR, Scott SA, Selvy PE, Kim K, Jadhav S, Morrison RD, Daniels JS, Brown HA, Lindsley CW
(2010) J Med Chem 53: 6706-19 - Electrochemical detection and characterization of proteins.
Smiechowski MF, Lvovich VF, Roy S, Fleischman A, Fissell WH, Riga AT
(2006) Biosens Bioelectron 22: 670-7 - Identification of a TAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentiation.
Xu Z, Huang S, Chang LS, Agulnick AD, Brandt SJ
(2003) Mol Cell Biol 23: 7585-99 - GDF-15, Galectin 3, Soluble ST2, and Risk of Mortality and Cardiovascular Events in CKD.
Tuegel C, Katz R, Alam M, Bhat Z, Bellovich K, de Boer I, Brosius F, Gadegbeku C, Gipson D, Hawkins J, Himmelfarb J, Ju W, Kestenbaum B, Kretzler M, Robinson-Cohen C, Steigerwalt S, Bansal N
(2018) Am J Kidney Dis 72: 519-528
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