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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Osteoclasts are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Osteoclasts.
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- Boning up on ephrin signaling.
Mundy GR, Elefteriou F
(2006) Cell 126: 441-3 - MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL.
Lynch CC, Hikosaka A, Acuff HB, Martin MD, Kawai N, Singh RK, Vargo-Gogola TC, Begtrup JL, Peterson TE, Fingleton B, Shirai T, Matrisian LM, Futakuchi M
(2005) Cancer Cell 7: 485-96 - ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae.
Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G
(2006) Cell Metab 4: 441-51 - Hedgehog coordination of postnatal osteoclast and osteoblast activities.
Mundy GR, Yang X
(2008) Dev Cell 14: 637-8 - A new dress code for MMPs: cleavage optional.
Fingleton B, Lynch CC
(2010) Dev Cell 18: 3-4 - Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion.
Raghu H, Cruz C, Rewerts CL, Frederick MD, Thornton S, Mullins ES, Schoenecker JG, Degen JL, Flick MJ
(2015) Blood 125: 427-37 - Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis.
Tai YT, Fulciniti M, Hideshima T, Song W, Leiba M, Li XF, Rumizen M, Burger P, Morrison A, Podar K, Chauhan D, Tassone P, Richardson P, Munshi NC, Ghobrial IM, Anderson KC
(2007) Blood 110: 1656-63 - Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis.
Thiolloy S, Halpern J, Holt GE, Schwartz HS, Mundy GR, Matrisian LM, Lynch CC
(2009) Cancer Res 69: 6747-55 - Tie2 signaling regulates osteoclastogenesis and osteolytic bone invasion of breast cancer.
Min Y, Ren X, Vaught DB, Chen J, Donnelly E, Lynch CC, Lin PC
(2010) Cancer Res 70: 2819-28 - FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation.
Karolak MR, Yang X, Elefteriou F
(2015) Hum Mol Genet 24: 2552-64 - Bisphosphonates inhibit osteosarcoma-mediated osteolysis via attenuation of tumor expression of MCP-1 and RANKL.
Ohba T, Cole HA, Cates JM, Slosky DA, Haro H, Ando T, Schwartz HS, Schoenecker JG
(2014) J Bone Miner Res 29: 1431-45 - The primary function of gp130 signaling in osteoblasts is to maintain bone formation and strength, rather than promote osteoclast formation.
Johnson RW, Brennan HJ, Vrahnas C, Poulton IJ, McGregor NE, Standal T, Walker EC, Koh TT, Nguyen H, Walsh NC, Forwood MR, Martin TJ, Sims NA
(2014) J Bone Miner Res 29: 1492-505 - Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling.
Edwards JR, Perrien DS, Fleming N, Nyman JS, Ono K, Connelly L, Moore MM, Lwin ST, Yull FE, Mundy GR, Elefteriou F
(2013) J Bone Miner Res 28: 960-9 - Localization and possible role of two different alpha v beta 3 integrin conformations in resting and resorbing osteoclasts.
Faccio R, Grano M, Colucci S, Villa A, Giannelli G, Quaranta V, Zallone A
(2002) J Cell Sci 115: 2919-29 - Human osteoclast-like cells selectively recognize laminin isoforms, an event that induces migration and activates Ca2+ mediated signals.
Colucci S, Giannelli G, Grano M, Faccio R, Quaranta V, Zallone AZ
(1996) J Cell Sci 109 ( Pt 6): 1527-35 - Staphylococcus aureus Infects Osteoclasts and Replicates Intracellularly.
Krauss JL, Roper PM, Ballard A, Shih CC, Fitzpatrick JAJ, Cassat JE, Ng PY, Pavlos NJ, Veis DJ
(2019) mBio 10: - Neuronal signaling and the regulation of bone remodeling.
Elefteriou F
(2005) Cell Mol Life Sci 62: 2339-49 - Loss of Nrf2 accelerates ionizing radiation-induced bone loss by upregulating RANKL.
Rana T, Schultz MA, Freeman ML, Biswas S
(2012) Free Radic Biol Med 53: 2298-307 - Effects of anti-tumor necrosis factor α agents on bone.
Kawai VK, Stein CM, Perrien DS, Griffin MR
(2012) Curr Opin Rheumatol 24: 576-85 - Multiple actions of parathyroid hormone-related protein in breast cancer bone metastasis.
Martin TJ, Johnson RW
(2021) Br J Pharmacol 178: 1923-1935 - Knockout of the murine prostaglandin EP2 receptor impairs osteoclastogenesis in vitro.
Li X, Okada Y, Pilbeam CC, Lorenzo JA, Kennedy CR, Breyer RM, Raisz LG
(2000) Endocrinology 141: 2054-61 - Extracellular norepinephrine clearance by the norepinephrine transporter is required for skeletal homeostasis.
Ma Y, Krueger JJ, Redmon SN, Uppuganti S, Nyman JS, Hahn MK, Elefteriou F
(2013) J Biol Chem 288: 30105-30113 - Bone turnover across the menopause transition : The role of gonadal inhibins.
Nicks KM, Fowler TW, Akel NS, Perrien DS, Suva LJ, Gaddy D
(2010) Ann N Y Acad Sci 1192: 153-60 - Impact of sarA and Phenol-Soluble Modulins on the Pathogenesis of Osteomyelitis in Diverse Clinical Isolates of Staphylococcus aureus.
Loughran AJ, Gaddy D, Beenken KE, Meeker DG, Morello R, Zhao H, Byrum SD, Tackett AJ, Cassat JE, Smeltzer MS
(2016) Infect Immun 84: 2586-94 - Regulation of osteoblastogenesis and osteoclastogenesis by the other reproductive hormones, Activin and Inhibin.
Nicks KM, Perrien DS, Akel NS, Suva LJ, Gaddy D
(2009) Mol Cell Endocrinol 310: 11-20 - Activation of NF-kappa B signaling promotes growth of prostate cancer cells in bone.
Jin R, Sterling JA, Edwards JR, DeGraff DJ, Lee C, Park SI, Matusik RJ
(2013) PLoS One 8: e60983 - Osteoclasts in multiple myeloma are derived from Gr-1+CD11b+myeloid-derived suppressor cells.
Zhuang J, Zhang J, Lwin ST, Edwards JR, Edwards CM, Mundy GR, Yang X
(2012) PLoS One 7: e48871 - Matrix rigidity induces osteolytic gene expression of metastatic breast cancer cells.
Ruppender NS, Merkel AR, Martin TJ, Mundy GR, Sterling JA, Guelcher SA
(2010) PLoS One 5: e15451 - Anti-transforming growth factor ß antibody treatment rescues bone loss and prevents breast cancer metastasis to bone.
Biswas S, Nyman JS, Alvarez J, Chakrabarti A, Ayres A, Sterling J, Edwards J, Rana T, Johnson R, Perrien DS, Lonning S, Shyr Y, Matrisian LM, Mundy GR
(2011) PLoS One 6: e27090 - The proto-oncogene function of Mdm2 in bone.
Olivos DJ, Perrien DS, Hooker A, Cheng YH, Fuchs RK, Hong JM, Bruzzaniti A, Chun K, Eischen CM, Kacena MA, Mayo LD
(2018) J Cell Biochem 119: 8830-8840 - Lysine392, a K63-linked ubiquitination site in NEMO, mediates inflammatory osteoclastogenesis and osteolysis.
Alhawagri M, Yamanaka Y, Ballard D, Oltz E, Abu-Amer Y
(2012) J Orthop Res 30: 554-60 - Diagnostic value of histone 3 mutations in osteoclast-rich bone tumors.
Nohr E, Lee LH, Cates JM, Perizzolo M, Itani D
(2017) Hum Pathol 68: 119-127 - Alterations in osteoclast morphology following long-term 17beta-estradiol administration in the mouse.
Gruber HE, Puzanov IJ, Bennett M, Kumar V, Gordon B
(2001) BMC Cell Biol 2: 3 - D-amino acid inhibits biofilm but not new bone formation in an ovine model.
Harmata AJ, Ma Y, Sanchez CJ, Zienkiewicz KJ, Elefteriou F, Wenke JC, Guelcher SA
(2015) Clin Orthop Relat Res 473: 3951-61 - A mathematical model of bone remodeling dynamics for normal bone cell populations and myeloma bone disease.
Ayati BP, Edwards CM, Webb GF, Wikswo JP
(2010) Biol Direct 5: 28 - Hallmarks of Bone Metastasis.
Johnson RW, Suva LJ
(2018) Calcif Tissue Int 102: 141-151 - Prostaglandin receptor EP2 mediates PGE2 stimulated hypercalcemia in mice in vivo.
Li X, Tomita M, Pilbeam CC, Breyer RM, Raisz LG
(2002) Prostaglandins Other Lipid Mediat 67: 173-80 - Activation of alphav beta3 integrin on human osteoclast-like cells stimulates adhesion and migration in response to osteopontin.
Faccio R, Grano M, Colucci S, Zallone AZ, Quaranta V, Pelletier AJ
(1998) Biochem Biophys Res Commun 249: 522-5
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