Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation. Omatsu Y, Seike M, Sugiyama T, Kume T, Nagasawa T (2014) Nature 508: 536-40 Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice. Rickert RC, Rajewsky K, Roes J (1995) Nature 376: 352-5 A severe combined immunodeficiency mutation in the mouse. Bosma GC, Custer RP, Bosma MJ (1983) Nature 301: 527-30 Syk tyrosine kinase required for mouse viability and B-cell development. Cheng AM, Rowley B, Pao W, Hayday A, Bolen JB, Pawson T (1995) Nature 378: 303-6 Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death. Hicks GG, Singh N, Nashabi A, Mai S, Bozek G, Klewes L, Arapovic D, White EK, Koury MJ, Oltz EM, Van Kaer L, Ruley HE (2000) Nat Genet 24: 175-9 Isoform-specific effects of apolipoprotein E on atherogenesis: gene transduction studies in mice. Yoshida H, Hasty AH, Major AS, Ishiguro H, Su YR, Gleaves LA, Babaev VR, Linton MF, Fazio S (2001) Circulation 104: 2820-5 Cyclooxygenase-1 deficiency in bone marrow cells increases early atherosclerosis in apolipoprotein E- and low-density lipoprotein receptor-null mice. Babaev VR, Ding L, Reese J, Morrow JD, Breyer MD, Dey SK, Fazio S, Linton MF (2006) Circulation 113: 108-17 CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow. Beck TC, Gomes AC, Cyster JG, Pereira JP (2014) J Exp Med 211: 2567-81 Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus. Johansson C, Wetzel JD, He J, Mikacenic C, Dermody TS, Kelsall BL (2007) J Exp Med 204: 1349-58 Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells. Crossno JT, Majka SM, Grazia T, Gill RG, Klemm DJ (2006) J Clin Invest 116: 3220-8 Evidence that fibroblasts derive from epithelium during tissue fibrosis. Iwano M, Plieth D, Danoff TM, Xue C, Okada H, Neilson EG (2002) J Clin Invest 110: 341-50 Constitutive production of macrophage colony-stimulating factor by human ovarian and breast cancer cell lines. Ramakrishnan S, Xu FJ, Brandt SJ, Niedel JE, Bast RC, Brown EL (1989) J Clin Invest 83: 921-6 Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration. Majka SM, Jackson KA, Kienstra KA, Majesky MW, Goodell MA, Hirschi KK (2003) J Clin Invest 111: 71-9 HDAC3 is essential for DNA replication in hematopoietic progenitor cells. Summers AR, Fischer MA, Stengel KR, Zhao Y, Kaiser JF, Wells CE, Hunt A, Bhaskara S, Luzwick JW, Sampathi S, Chen X, Thompson MA, Cortez D, Hiebert SW (2013) J Clin Invest 123: 3112-23 Coronavirus replication does not require the autophagy gene ATG5. Zhao Z, Thackray LB, Miller BC, Lynn TM, Becker MM, Ward E, Mizushima NN, Denison MR, Virgin HW (2007) Autophagy 3: 581-5 Reply: Expanded Role for Bone Marrow-derived Hematopoietic Stem and Progenitor Cells in Pulmonary Arterial Hypertension. Yan L, West J, Hamid R (2016) Am J Respir Crit Care Med 194: 384-5 Follow-up of residual disease using metaphase-FISH in patients with acute lymphoblastic leukemia in remission. El-Rifai W, Ruutu T, Vettenranta K, Elonen E, Saarinen UM, Volin L, Knuutila S (1997) Leukemia 11: 633-8 Comparative genomic hybridization in childhood acute lymphoblastic leukemia. Larramendy ML, Huhta T, Vettenranta K, El-Rifai W, Lundin J, Pakkala S, Saarinen-Pihkala UM, Knuutila S (1998) Leukemia 12: 1638-44 Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis. Keller UB, Old JB, Dorsey FC, Nilsson JA, Nilsson L, MacLean KH, Chung L, Yang C, Spruck C, Boyd K, Reed SI, Cleveland JL (2007) EMBO J 26: 2562-74 Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death. Ko DC, Gamazon ER, Shukla KP, Pfuetzner RA, Whittington D, Holden TD, Brittnacher MJ, Fong C, Radey M, Ogohara C, Stark AL, Akey JM, Dolan ME, Wurfel MM, Miller SI (2012) Proc Natl Acad Sci U S A 109: E2343-52 De novo generation of white adipocytes from the myeloid lineage via mesenchymal intermediates is age, adipose depot, and gender specific. Majka SM, Fox KE, Psilas JC, Helm KM, Childs CR, Acosta AS, Janssen RC, Friedman JE, Woessner BT, Shade TR, Varella-Garcia M, Klemm DJ (2010) Proc Natl Acad Sci U S A 107: 14781-6 Specific recognition of human leukemic cells by allogeneic T cells: II. Evidence for HLA-D restricted determinants on leukemic cells that are crossreactive with determinants present on unrelated nonleukemic cells. Sosman JA, Oettel KR, Smith SD, Hank JA, Fisch P, Sondel PM (1990) Blood 75: 2005-16 The relative quiescence of hematopoietic stem cells in nonhuman primates. Mahmud N, Devine SM, Weller KP, Parmar S, Sturgeon C, Nelson MC, Hewett T, Hoffman R (2001) Blood 97: 3061-8 Human CD34(+) stem cells express the hiwi gene, a human homologue of the Drosophila gene piwi. Sharma AK, Nelson MC, Brandt JE, Wessman M, Mahmud N, Weller KP, Hoffman R (2001) Blood 97: 426-34 Synthesis of transforming growth factor-beta 1 by megakaryocytes and its localization to megakaryocyte and platelet alpha-granules. Fava RA, Casey TT, Wilcox J, Pelton RW, Moses HL, Nanney LB (1990) Blood 76: 1946-55 Selective roles for antiapoptotic MCL-1 during granulocyte development and macrophage effector function. Steimer DA, Boyd K, Takeuchi O, Fisher JK, Zambetti GP, Opferman JT (2009) Blood 113: 2805-15 Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis. Tai YT, Fulciniti M, Hideshima T, Song W, Leiba M, Li XF, Rumizen M, Burger P, Morrison A, Podar K, Chauhan D, Tassone P, Richardson P, Munshi NC, Ghobrial IM, Anderson KC (2007) Blood 110: 1656-63 Leukemia inhibitory factor upregulates cytokine expression by a murine stromal cell line enabling the maintenance of highly enriched competitive repopulating stem cells. Szilvassy SJ, Weller KP, Lin W, Sharma AK, Ho AS, Tsukamoto A, Hoffman R, Leiby KR, Gearing DP (1996) Blood 87: 4618-28 Natural killer T cells accelerate atherogenesis in mice. Nakai Y, Iwabuchi K, Fujii S, Ishimori N, Dashtsoodol N, Watano K, Mishima T, Iwabuchi C, Tanaka S, Bezbradica JS, Nakayama T, Taniguchi M, Miyake S, Yamamura T, Kitabatake A, Joyce S, Van Kaer L, Onoé K (2004) Blood 104: 2051-9 Negative regulation of activated alpha-2 integrins during thrombopoiesis. Zou Z, Schmaier AA, Cheng L, Mericko P, Dickeson SK, Stricker TP, Santoro SA, Kahn ML (2009) Blood 113: 6428-39 Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment. Acuff HB, Carter KJ, Fingleton B, Gorden DL, Matrisian LM (2006) Cancer Res 66: 259-66 Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment. Bierie B, Stover DG, Abel TW, Chytil A, Gorska AE, Aakre M, Forrester E, Yang L, Wagner KU, Moses HL (2008) Cancer Res 68: 1809-19 Parathyroid hormone-related protein drives a CD11b+Gr1+ cell-mediated positive feedback loop to support prostate cancer growth. Park SI, Lee C, Sadler WD, Koh AJ, Jones J, Seo JW, Soki FN, Cho SW, Daignault SD, McCauley LK (2013) Cancer Res 73: 6574-83 Proteasome inhibition drastically but reversibly impairs murine lymphocyte development. Maseda D, Meister S, Neubert K, Herrmann M, Voll RE (2008) Cell Death Differ 15: 600-12 Proapoptotic Bid mediates the Atr-directed DNA damage response to replicative stress. Liu Y, Bertram CC, Shi Q, Zinkel SS (2011) Cell Death Differ 18: 841-52 Hostile Takeover: Tregs Expand in IFNγ-Rich AML Microenvironment. Ferrell PB, Kordasti S (2022) Clin Cancer Res 28: 2986-2988 Regulation of differentiation by TGF-beta. Moses HL, Serra R (1996) Curr Opin Genet Dev 6: 581-6 Restriction landmark genome scanning for aberrant methylation in primary refractory and relapsed acute myeloid leukemia; involvement of the WIT-1 gene. Plass C, Yu F, Yu L, Strout MP, El-Rifai W, Elonen E, Knuutila S, Marcucci G, Young DC, Held WA, Bloomfield CD, Caligiuri MA (1999) Oncogene 18: 3159-65 Macrophage apolipoprotein A-I expression protects against atherosclerosis in ApoE-deficient mice and up-regulates ABC transporters. Su YR, Ishiguro H, Major AS, Dove DE, Zhang W, Hasty AH, Babaev VR, Linton MF, Fazio S (2003) Mol Ther 8: 576-83 A comprehensive analysis of transfection-assisted delivery of iron oxide nanoparticles to dendritic cells. Toki S, Omary RA, Wilson K, Gore JC, Peebles RS, Pham W (2013) Nanomedicine 9: 1235-44
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.