p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Wildenberg GA, Dohn MR, Carnahan RH, Davis MA, Lobdell NA, Settleman J, Reynolds AB (2006) Cell 127: 1027-39 Competition for related but nonidentical binding sites on the glycoprotein IIb-IIIa complex by peptides derived from platelet adhesive proteins. Santoro SA, Lawing WJ (1987) Cell 48: 867-73 A novel vitronectin receptor integrin (alpha v beta x) is responsible for distinct adhesive properties of carcinoma cells. Cheresh DA, Smith JW, Cooper HM, Quaranta V (1989) Cell 57: 59-69 Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis. Sakai T, Johnson KJ, Murozono M, Sakai K, Magnuson MA, Wieloch T, Cronberg T, Isshiki A, Erickson HP, Fässler R (2001) Nat Med 7: 324-30 Angiotensin II type 2 receptor is essential for left ventricular hypertrophy and cardiac fibrosis in chronic angiotensin II-induced hypertension. Ichihara S, Senbonmatsu T, Price E, Ichiki T, Gaffney FA, Inagami T (2001) Circulation 104: 346-51 Immunolocalization of alpha-integrin subunits and extracellular matrix components during human colonic organogenesis. Dieckgraefe BK, Santoro SA, Alpers DH (1996) Gastroenterology 110: 58-71 Collagen-induced release of interleukin 1 from human blood mononuclear cells. Potentiation by fibronectin binding to the alpha 5 beta 1 integrin. Pacifici R, Basilico C, Roman J, Zutter MM, Santoro SA, McCracken R (1992) J Clin Invest 89: 61-7 Regulation of extracellular matrix by mechanical stress in rat glomerular mesangial cells. Yasuda T, Kondo S, Homma T, Harris RC (1996) J Clin Invest 98: 1991-2000 Integrin cytoplasmic domains mediate inside-out signal transduction. O'Toole TE, Katagiri Y, Faull RJ, Peter K, Tamura R, Quaranta V, Loftus JC, Shattil SJ, Ginsberg MH (1994) J Cell Biol 124: 1047-59 Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin. Erdogan B, Ao M, White LM, Means AL, Brewer BM, Yang L, Washington MK, Shi C, Franco OE, Weaver AM, Hayward SW, Li D, Webb DJ (2017) J Cell Biol 216: 3799-3816 CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling. Féral CC, Zijlstra A, Tkachenko E, Prager G, Gardel ML, Slepak M, Ginsberg MH (2007) J Cell Biol 178: 701-11 Directional cell movement through tissues is controlled by exosome secretion. Sung BH, Ketova T, Hoshino D, Zijlstra A, Weaver AM (2015) Nat Commun 6: 7164 Inhibition of platelet aggregation by a monoclonal antibody against human fibronectin. Dixit VM, Haverstick DM, O'Rourke K, Hennessy SW, Broekelmann TJ, McDonald JA, Grant GA, Santoro SA, Frazier WA (1985) Proc Natl Acad Sci U S A 82: 3844-8 Cortactin controls cell motility and lamellipodial dynamics by regulating ECM secretion. Sung BH, Zhu X, Kaverina I, Weaver AM (2011) Curr Biol 21: 1460-9 Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by a synthetic tetrapeptide derived from the cell-binding domain of fibronectin. Haverstick DM, Cowan JF, Yamada KM, Santoro SA (1985) Blood 66: 946-52 Platelet interactions with fibronectin: divalent cation-independent platelet adhesion to the gelatin-binding domain of fibronectin. Winters KJ, Walsh JJ, Rubin BG, Santoro SA (1993) Blood 81: 1778-86 Fibronectins are essential for heart and blood vessel morphogenesis but are dispensable for initial specification of precursor cells. George EL, Baldwin HS, Hynes RO (1997) Blood 90: 3073-81 Reactivity of synthetic peptide analogs of adhesive proteins in regard to the interaction of human endothelial cells with extracellular matrix. Chen CS, Hawiger J (1991) Blood 77: 2200-6 Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by complex gangliosides. Santoro SA (1989) Blood 73: 484-9 Failure of antioxidant therapy to attenuate interstitial disease in rats with reversible nephrotic syndrome. Drukker A, Eddy AA (1998) J Am Soc Nephrol 9: 243-51 In vitro and in vivo models analyzing von Hippel-Lindau disease-specific mutations. Rathmell WK, Hickey MM, Bezman NA, Chmielecki CA, Carraway NC, Simon MC (2004) Cancer Res 64: 8595-603 Human carcinoid cell production of paracrine growth factors that can stimulate fibroblast and endothelial cell growth. Beauchamp RD, Coffey RJ, Lyons RM, Perkett EA, Townsend CM, Moses HL (1991) Cancer Res 51: 5253-60 A monoclonal antibody inhibits adhesion to fibronectin and vitronectin of a colon carcinoma cell line and recognizes the integrins alpha v beta 3, alpha v beta 5, and alpha v beta 6. Lehmann M, Rabenandrasana C, Tamura R, Lissitzky JC, Quaranta V, Pichon J, Marvaldi J (1994) Cancer Res 54: 2102-7 Plasminogen activator inhibitor-1 deficiency protects against aldosterone-induced glomerular injury. Ma J, Weisberg A, Griffin JP, Vaughan DE, Fogo AB, Brown NJ (2006) Kidney Int 69: 1064-72 Effects of sulfonylureas, alpha-endosulfine counterparts, on glomerulosclerosis in type 1 and type 2 models of diabetes. Biederman JI, Vera E, Rankhaniya R, Hassett C, Giannico G, Yee J, Cortes P (2005) Kidney Int 67: 554-65 Pharmacological inhibition and genetic deficiency of plasminogen activator inhibitor-1 attenuates angiotensin II/salt-induced aortic remodeling. Weisberg AD, Albornoz F, Griffin JP, Crandall DL, Elokdah H, Fogo AB, Vaughan DE, Brown NJ (2005) Arterioscler Thromb Vasc Biol 25: 365-71 Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin: incisional wound model. Quaglino D, Nanney LB, Ditesheim JA, Davidson JM (1991) J Invest Dermatol 97: 34-42 Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape. Sims JR, Karp S, Ingber DE (1992) J Cell Sci 103 ( Pt 4): 1215-22 Integrin-dependent PLC-gamma1 phosphorylation mediates fibronectin-dependent adhesion. Tvorogov D, Wang XJ, Zent R, Carpenter G (2005) J Cell Sci 118: 601-10 Transforming growth factor beta mimetics: discovery of 7-[4-(4-cyanophenyl)phenoxy]-heptanohydroxamic acid, a biaryl hydroxamate inhibitor of histone deacetylase. Glaser KB, Li J, Aakre ME, Morgan DW, Sheppard G, Stewart KD, Pollock J, Lee P, O'Connor CZ, Anderson SN, Mussatto DJ, Wegner CW, Moses HL (2002) Mol Cancer Ther 1: 759-68 pVHL function is essential for endothelial extracellular matrix deposition. Tang N, Mack F, Haase VH, Simon MC, Johnson RS (2006) Mol Cell Biol 26: 2519-30 Cellular traction stresses mediate extracellular matrix degradation by invadopodia. Jerrell RJ, Parekh A (2014) Acta Biomater 10: 1886-96 Identification and characterization of a conformational heparin-binding site involving two fibronectin type III modules of bovine tenascin-X. Lethias C, Elefteriou F, Parsiegla G, Exposito JY, Garrone R (2001) J Biol Chem 276: 16432-8 Regulation of mRNAs for type-1 plasminogen activator inhibitor, fibronectin, and type I procollagen by transforming growth factor-beta. Divergent responses in lung fibroblasts and carcinoma cells. Keski-Oja J, Raghow R, Sawdey M, Loskutoff DJ, Postlethwaite AE, Kang AH, Moses HL (1988) J Biol Chem 263: 3111-5 Endo180 binds to the C-terminal region of type I collagen. Thomas EK, Nakamura M, Wienke D, Isacke CM, Pozzi A, Liang P (2005) J Biol Chem 280: 22596-605 Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells. Miller CG, Pozzi A, Zent R, Schwarzbauer JE (2014) Mol Biol Cell 25: 2342-50 Bves and NDRG4 regulate directional epicardial cell migration through autocrine extracellular matrix deposition. Benesh EC, Miller PM, Pfaltzgraff ER, Grega-Larson NE, Hager HA, Sung BH, Qu X, Baldwin HS, Weaver AM, Bader DM (2013) Mol Biol Cell 24: 3496-510 Focal adhesion kinase modulates cell adhesion strengthening via integrin activation. Michael KE, Dumbauld DW, Burns KL, Hanks SK, García AJ (2009) Mol Biol Cell 20: 2508-19 Integrin alpha 6A beta 1 induces CD81-dependent cell motility without engaging the extracellular matrix migration substrate. Domanico SZ, Pelletier AJ, Havran WL, Quaranta V (1997) Mol Biol Cell 8: 2253-65
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.