Keyword Connections

•  Albert Beth
•  Charles Sanders

•  Mark Vincent dela Cerna
•  Romell Gletten

•  Todd Graham

Resources

• No matching connections

Communities

• No matching connections

Publications

• Rational use of analgesic and antiinflammatory drugs.
  Crofford LJ
  (2001) N Engl J Med 345: 1844-6
• Inactivating mutations in NPC1L1 and protection from coronary heart disease.
  Myocardial Infarction Genetics Consortium Investigators, Stitziel NO, Won HH, Morrison AC, Peloso GM, Do R, Lange LA, Fontanillas P, Gupta N, Duga S, Goel A, Farrall M, Saleheen D, Ferrario P, König I, Asselta R, Merlini PA, Marziliano N, Notarangelo MF, Schick U, Auer P, Assimes TL, Reilly M, Wilensky R, Rader DJ, Hovingh GK, Meitinger T, Kessler T, Kastrati A, Laugwitz KL, Siscovick D, Rotter JI, Hazen SL, Tracy R, Cresci S, Spertus J, Jackson R, Schwartz SM, Natarajan P, Crosby J, Muzny D, Ballantyne C, Rich SS, O'Donnell CJ, Abecasis G, Sunaev S, Nickerson DA, Buring JE, Ridker PM, Chasman DI, Austin E, Kullo IJ, Weeke PE, Shaffer CM, Bastarache LA, Denny JC, Roden DM, Palmer C, Deloukas P, Lin DY, Tang ZZ, Erdmann J, Schunkert H, Danesh J, Marrugat J, Elosua R, Ardissino D, McPherson R, Watkins H, Reiner AP, Wilson JG, Altshuler D, Gibbs RA, Lander ES, Boerwinkle E, Gabriel S, Kathiresan S
  (2014) N Engl J Med 371: 2072-82
• Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency.
  Shannon JR, Flattem NL, Jordan J, Jacob G, Black BK, Biaggioni I, Blakely RD, Robertson D
  (2000) N Engl J Med 342: 541-9
• Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis.
  Marinko JT, Huang H, Penn WD, Capra JA, Schlebach JP, Sanders CR
  (2019) Chem Rev 119: 5537-5606
• COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease.
  Ray WA, Stein CM, Daugherty JR, Hall K, Arbogast PG, Griffin MR
  (2002) Lancet 360: 1071-3
• Proteogenomic characterization of human colon and rectal cancer.
  Zhang B, Wang J, Wang X, Zhu J, Liu Q, Shi Z, Chambers MC, Zimmerman LJ, Shaddox KF, Kim S, Davies SR, Wang S, Wang P, Kinsinger CR, Rivers RC, Rodriguez H, Townsend RR, Ellis MJ, Carr SA, Tabb DL, Coffey RJ, Slebos RJ, Liebler DC, NCI CPTAC
  (2014) Nature 513: 382-7
• Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants.
  Hemann MT, Bric A, Teruya-Feldstein J, Herbst A, Nilsson JA, Cordon-Cardo C, Cleveland JL, Tansey WP, Lowe SW
  (2005) Nature 436: 807-11
• HIV: Antiviral action countered by Nef.
  Aiken C
  (2015) Nature 526: 202-3
• An RNA-export mediator with an essential nuclear export signal.
  Murphy R, Wente SR
  (1996) Nature 383: 357-60
• A stomatin-like protein necessary for mechanosensation in C. elegans.
  Huang M, Gu G, Ferguson EL, Chalfie M
  (1995) Nature 378: 292-5
• Patched acts catalytically to suppress the activity of Smoothened.
  Taipale J, Cooper MK, Maiti T, Beachy PA
  (2002) Nature 418: 892-7
• Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.
  Taipale J, Chen JK, Cooper MK, Wang B, Mann RK, Milenkovic L, Scott MP, Beachy PA
  (2000) Nature 406: 1005-9
• Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter.
  Pacholczyk T, Blakely RD, Amara SG
  (1991) Nature 350: 350-4
• Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.
  Huppert SS, Le A, Schroeter EH, Mumm JS, Saxena MT, Milner LA, Kopan R
  (2000) Nature 405: 966-70
• Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms.
  Chen L, Chetkovich DM, Petralia RS, Sweeney NT, Kawasaki Y, Wenthold RJ, Bredt DS, Nicoll RA
  (2000) Nature 408: 936-43
• A genome-wide linkage and association scan reveals novel loci for autism.
  Weiss LA, Arking DE, Gene Discovery Project of Johns Hopkins & the Autism Consortium, Daly MJ, Chakravarti A
  (2009) Nature 461: 802-8
• Sonic hedgehog is essential to foregut development.
  Litingtung Y, Lei L, Westphal H, Chiang C
  (1998) Nat Genet 20: 58-61
• A second signal recognition event required for translocation into the endoplasmic reticulum.
  Siegel V
  (1995) Cell 82: 167-70
• Perp is a p63-regulated gene essential for epithelial integrity.
  Ihrie RA, Marques MR, Nguyen BT, Horner JS, Papazoglu C, Bronson RT, Mills AA, Attardi LD
  (2005) Cell 120: 843-56
• A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor.
  Trofatter JA, MacCollin MM, Rutter JL, Murrell JR, Duyao MP, Parry DM, Eldridge R, Kley N, Menon AG, Pulaski K
  (1993) Cell 72: 791-800
• Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice.
  Lazarov O, Robinson J, Tang YP, Hairston IS, Korade-Mirnics Z, Lee VM, Hersh LB, Sapolsky RM, Mirnics K, Sisodia SS
  (2005) Cell 120: 701-13
• Recognition of a transmembrane domain: another role for the ribosome?
  Siegel V
  (1997) Cell 90: 5-8
• H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection.
  Martin WD, Hicks GG, Mendiratta SK, Leva HI, Ruley HE, Van Kaer L
  (1996) Cell 84: 543-50
• Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein.
  Bowman AB, Kamal A, Ritchings BW, Philp AV, McGrail M, Gindhart JG, Goldstein LS
  (2000) Cell 103: 583-94
• Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants.
  Ramamoorthy S, Blakely RD
  (1999) Science 285: 763-6
• A sperm cytoskeletal protein that signals oocyte meiotic maturation and ovulation.
  Miller MA, Nguyen VQ, Lee MH, Kosinski M, Schedl T, Caprioli RM, Greenstein D
  (2001) Science 291: 2144-7
• Gatekeepers of the nucleus.
  Wente SR
  (2000) Science 288: 1374-7
• Site of G protein binding to rhodopsin mapped with synthetic peptides from the alpha subunit.
  Hamm HE, Deretic D, Arendt A, Hargrave PA, Koenig B, Hofmann KP
  (1988) Science 241: 832-5
• Global analysis of protein activities using proteome chips.
  Zhu H, Bilgin M, Bangham R, Hall D, Casamayor A, Bertone P, Lan N, Jansen R, Bidlingmaier S, Houfek T, Mitchell T, Miller P, Dean RA, Gerstein M, Snyder M
  (2001) Science 293: 2101-5
• Suppression of aging in mice by the hormone Klotho.
  Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, Kuro-o M
  (2005) Science 309: 1829-33
• Aspirin-like molecules that covalently inactivate cyclooxygenase-2.
  Kalgutkar AS, Crews BC, Rowlinson SW, Garner C, Seibert K, Marnett LJ
  (1998) Science 280: 1268-70
• Teratogen-mediated inhibition of target tissue response to Shh signaling.
  Cooper MK, Porter JA, Young KE, Beachy PA
  (1998) Science 280: 1603-7
• Neurobiology. Dopamine's reversal of fortune.
  Blakely RD
  (2001) Science 293: 2407-9
• An essential role for ectodomain shedding in mammalian development.
  Peschon JJ, Slack JL, Reddy P, Stocking KL, Sunnarborg SW, Lee DC, Russell WE, Castner BJ, Johnson RS, Fitzner JN, Boyce RW, Nelson N, Kozlosky CJ, Wolfson MF, Rauch CT, Cerretti DP, Paxton RJ, March CJ, Black RA
  (1998) Science 282: 1281-4
• Medulloblastoma growth inhibition by hedgehog pathway blockade.
  Berman DM, Karhadkar SS, Hallahan AR, Pritchard JI, Eberhart CG, Watkins DN, Chen JK, Cooper MK, Taipale J, Olson JM, Beachy PA
  (2002) Science 297: 1559-61
• Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.
  Sattler M, Liang H, Nettesheim D, Meadows RP, Harlan JE, Eberstadt M, Yoon HS, Shuker SB, Chang BS, Minn AJ, Thompson CB, Fesik SW
  (1997) Science 275: 983-6
• G protein betagamma subunit-mediated presynaptic inhibition: regulation of exocytotic fusion downstream of Ca2+ entry.
  Blackmer T, Larsen EC, Takahashi M, Martin TF, Alford S, Hamm HE
  (2001) Science 292: 293-7
• Systematic identification of signal-activated stochastic gene regulation.
  Neuert G, Munsky B, Tan RZ, Teytelman L, Khammash M, van Oudenaarden A
  (2013) Science 339: 584-7