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•  Igor Feoktistov

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Publications

• Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
  Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR
  (2017) Nature 551: 464-471
• Prostacyclin inhibits mobilisation of fibrinogen-binding sites on human ADP- and thrombin-treated platelets.
  Hawiger J, Parkinson S, Timmons S
  (1980) Nature 283: 195-7
• Adenosine diphosphate induces binding of von Willebrand factor to human platelets.
  Fujimoto T, Hawiger J
  (1982) Nature 297: 154-6
• Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.
  Huang DT, Hunt HW, Zhuang M, Ohi MD, Holton JM, Schulman BA
  (2007) Nature 445: 394-8
• Regulation of serotonin-2C receptor G-protein coupling by RNA editing.
  Burns CM, Chu H, Rueter SM, Hutchinson LK, Canton H, Sanders-Bush E, Emeson RB
  (1997) Nature 387: 303-8
• Regulation of alternative splicing by RNA editing.
  Rueter SM, Dawson TR, Emeson RB
  (1999) Nature 399: 75-80
• Telomere dysfunction induces metabolic and mitochondrial compromise.
  Sahin E, Colla S, Liesa M, Moslehi J, Müller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, Shukla SA, Jaskelioff M, Martin ES, Heffernan TP, Protopopov A, Ivanova E, Mahoney JE, Kost-Alimova M, Perry SR, Bronson R, Liao R, Mulligan R, Shirihai OS, Chin L, DePinho RA
  (2011) Nature 470: 359-65
• Dynamic landscape and regulation of RNA editing in mammals.
  Tan MH, Li Q, Shanmugam R, Piskol R, Kohler J, Young AN, Liu KI, Zhang R, Ramaswami G, Ariyoshi K, Gupte A, Keegan LP, George CX, Ramu A, Huang N, Pollina EA, Leeman DS, Rustighi A, Goh YPS, GTEx Consortium, Laboratory, Data Analysis &Coordinating Center (LDACC)—Analysis Working Group, Statistical Methods groups—Analysis Working Group, Enhancing GTEx (eGTEx) groups, NIH Common Fund, NIH/NCI, NIH/NHGRI, NIH/NIMH, NIH/NIDA, Biospecimen Collection Source Site—NDRI, Biospecimen Collection Source Site—RPCI, Biospecimen Core Resource—VARI, Brain Bank Repository—University of Miami Brain Endowment Bank, Leidos Biomedical—Project Management, ELSI Study, Genome Browser Data Integration &Visualization—EBI, Genome Browser Data Integration &Visualization—UCSC Genomics Institute, University of California Santa Cruz, Chawla A, Del Sal G, Peltz G, Brunet A, Conrad DF, Samuel CE, O'Connell MA, Walkley CR, Nishikura K, Li JB
  (2017) Nature 550: 249-254
• Targeting Plasmodium PI(4)K to eliminate malaria.
  McNamara CW, Lee MC, Lim CS, Lim SH, Roland J, Simon O, Yeung BK, Chatterjee AK, McCormack SL, Manary MJ, Zeeman AM, Dechering KJ, Kumar TS, Henrich PP, Gagaring K, Ibanez M, Kato N, Kuhen KL, Fischli C, Nagle A, Rottmann M, Plouffe DM, Bursulaya B, Meister S, Rameh L, Trappe J, Haasen D, Timmerman M, Sauerwein RW, Suwanarusk R, Russell B, Renia L, Nosten F, Tully DC, Kocken CH, Glynne RJ, Bodenreider C, Fidock DA, Diagana TT, Winzeler EA
  (2013) Nature 504: 248-253
• Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes.
  Silva JP, Köhler M, Graff C, Oldfors A, Magnuson MA, Berggren PO, Larsson NG
  (2000) Nat Genet 26: 336-40
• The solution structure of the ADAR2 dsRBM-RNA complex reveals a sequence-specific readout of the minor groove.
  Stefl R, Oberstrass FC, Hood JL, Jourdan M, Zimmermann M, Skrisovska L, Maris C, Peng L, Hofr C, Emeson RB, Allain FH
  (2010) Cell 143: 225-37
• The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators.
  Lee D, Ezhkova E, Li B, Pattenden SG, Tansey WP, Workman JL
  (2005) Cell 123: 423-36
• The power of pumping together; deconstructing the engine of a DNA replication machine.
  Eichman BF, Fanning E
  (2004) Cell 119: 3-4
• HIF-1alpha is essential for myeloid cell-mediated inflammation.
  Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS
  (2003) Cell 112: 645-57
• Regulation of chromatin remodeling by inositol polyphosphates.
  Steger DJ, Haswell ES, Miller AL, Wente SR, O'Shea EK
  (2003) Science 299: 114-6
• Solution nuclear magnetic resonance structure of membrane-integral diacylglycerol kinase.
  Van Horn WD, Kim HJ, Ellis CD, Hadziselimovic A, Sulistijo ES, Karra MD, Tian C, Sönnichsen FD, Sanders CR
  (2009) Science 324: 1726-9
• Restoring auditory cortex plasticity in adult mice by restricting thalamic adenosine signaling.
  Blundon JA, Roy NC, Teubner BJW, Yu J, Eom TY, Sample KJ, Pani A, Smeyne RJ, Han SB, Kerekes RA, Rose DC, Hackett TA, Vuppala PK, Freeman BB, Zakharenko SS
  (2017) Science 356: 1352-1356
• Molecular basis for interactions of G protein betagamma subunits with effectors.
  Ford CE, Skiba NP, Bae H, Daaka Y, Reuveny E, Shekter LR, Rosal R, Weng G, Yang CS, Iyengar R, Miller RJ, Jan LY, Lefkowitz RJ, Hamm HE
  (1998) Science 280: 1271-4
• Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome.
  Verma R, Aravind L, Oania R, McDonald WH, Yates JR, Koonin EV, Deshaies RJ
  (2002) Science 298: 611-5
• Glutamate receptor RNA editing in vitro by enzymatic conversion of adenosine to inosine.
  Rueter SM, Burns CM, Coode SA, Mookherjee P, Emeson RB
  (1995) Science 267: 1491-4
• Neurobiology. Dopamine's reversal of fortune.
  Blakely RD
  (2001) Science 293: 2407-9
• Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase.
  Hunter RW, Hughey CC, Lantier L, Sundelin EI, Peggie M, Zeqiraj E, Sicheri F, Jessen N, Wasserman DH, Sakamoto K
  (2018) Nat Med 24: 1395-1406
• A channel to neurodegeneration.
  Deutch AY, Winder DG
  (2006) Nat Med 12: 17-8
• Adenosine A2B receptors.
  Feoktistov I, Biaggioni I
  (1997) Pharmacol Rev 49: 381-402
• The epidermal growth factor receptor: from mutant oncogene in nonhuman cancers to therapeutic target in human neoplasia.
  Arteaga CL
  (2001) J Clin Oncol 19: 32S-40S
• ATP serves as a negative feedback inhibitor of voltage-gated Ca2+ channel currents in cultured bovine adrenal chromaffin cells.
  Currie KP, Fox AP
  (1996) Neuron 16: 1027-36
• Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions.
  Nair KS, Hanson SM, Mendez A, Gurevich EV, Kennedy MJ, Shestopalov VI, Vishnivetskiy SA, Chen J, Hurley JB, Gurevich VV, Slepak VZ
  (2005) Neuron 46: 555-67
• Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3.
  Ezhkova E, Tansey WP
  (2004) Mol Cell 13: 435-42
• Visualizing a circadian clock protein: crystal structure of KaiC and functional insights.
  Pattanayek R, Wang J, Mori T, Xu Y, Johnson CH, Egli M
  (2004) Mol Cell 15: 375-88
• Endothelial modulation of the coronary vasculature in vessels perfused via mature collaterals.
  Sellke FW, Quillen JE, Brooks LA, Harrison DG
  (1990) Circulation 81: 1938-47
• Blockade of nucleoside transport is required for delivery of intraarterial adenosine into the interstitium: relevance to therapeutic preconditioning in humans.
  Gamboa A, Ertl AC, Costa F, Farley G, Manier ML, Hachey DL, Diedrich A, Biaggioni I
  (2003) Circulation 108: 2631-5
• Adenosine increases sympathetic nerve traffic in humans.
  Biaggioni I, Killian TJ, Mosqueda-Garcia R, Robertson RM, Robertson D
  (1991) Circulation 83: 1668-75
• Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis.
  Saunders DC, Brissova M, Phillips N, Shrestha S, Walker JT, Aramandla R, Poffenberger G, Flaherty DK, Weller KP, Pelletier J, Cooper T, Goff MT, Virostko J, Shostak A, Dean ED, Greiner DL, Shultz LD, Prasad N, Levy SE, Carnahan RH, Dai C, Sévigny J, Powers AC
  (2019) Cell Metab 29: 745-754.e4
• An arginine tetrad as mediator of input-dependent and input-independent ATPases in the clock protein KaiC.
  Pattanayek R, Xu Y, Lamichhane A, Johnson CH, Egli M
  (2014) Acta Crystallogr D Biol Crystallogr 70: 1375-90
• Antiangiogenic agents protect liver sinusoidal lining cells from cold preservation injury in rat liver transplantation.
  Gao W, Washington MK, Bentley RC, Clavien PA
  (1997) Gastroenterology 113: 1692-700