Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions. Mili S, Moissoglu K, Macara IG (2008) Nature 453: 115-9 How do microtubules guide migrating cells? Small JV, Geiger B, Kaverina I, Bershadsky A (2002) Nat Rev Mol Cell Biol 3: 957-64 Organization and execution of the epithelial polarity programme. Rodriguez-Boulan E, Macara IG (2014) Nat Rev Mol Cell Biol 15: 225-42 Cytokinesis monitoring during development; rapid pole-to-pole shuttling of a signaling protein by localized kinase and phosphatase in Caulobacter. Matroule JY, Lam H, Burnette DT, Jacobs-Wagner C (2004) Cell 118: 579-90 Polarity and differential inheritance--universal attributes of life? Macara IG, Mili S (2008) Cell 135: 801-12 An unusual mosaic protein with a protease domain, encoded by the nudel gene, is involved in defining embryonic dorsoventral polarity in Drosophila. Hong CC, Hashimoto C (1995) Cell 82: 785-94 Colonocyte metabolism shapes the gut microbiota. Litvak Y, Byndloss MX, Bäumler AJ (2018) Science 362: Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis. McCaffrey LM, Montalbano J, Mihai C, Macara IG (2012) Cancer Cell 22: 601-14 Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells. Miller PM, Folkmann AW, Maia AR, Efimova N, Efimov A, Kaverina I (2009) Nat Cell Biol 11: 1069-80 EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity. Löf-Öhlin ZM, Nyeng P, Bechard ME, Hess K, Bankaitis E, Greiner TU, Ameri J, Wright CV, Semb H (2017) Nat Cell Biol 19: 1313-1325 The Par3-like polarity protein Par3L is essential for mammary stem cell maintenance. Huo Y, Macara IG (2014) Nat Cell Biol 16: 529-37 Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells. Singh B, Coffey RJ (2014) Annu Rev Physiol 76: 275-300 PTK7-Src signaling at epithelial cell contacts mediates spatial organization of actomyosin and planar cell polarity. Andreeva A, Lee J, Lohia M, Wu X, Macara IG, Lu X (2014) Dev Cell 29: 20-33 Cytoskeletal interactions with the outside world. Weaver AM (2005) Dev Cell 9: 35-8 Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development. Moon KH, Kim HT, Lee D, Rao MB, Levine EM, Lim DS, Kim JW (2018) Dev Cell 44: 13-28.e3 Tea4p links microtubule plus ends with the formin for3p in the establishment of cell polarity. Martin SG, McDonald WH, Yates JR, Chang F (2005) Dev Cell 8: 479-91 The PAR proteins: fundamental players in animal cell polarization. Goldstein B, Macara IG (2007) Dev Cell 13: 609-622 The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase. Zhang H, Macara IG (2008) Dev Cell 14: 216-26 Pancreas-specific ablation of beta1 integrin induces tissue degeneration by disrupting acinar cell polarity. Bombardelli L, Carpenter ES, Wu AP, Alston N, DelGiorno KE, Crawford HC (2010) Gastroenterology 138: 2531-40, 2540.e1-4 KSR1 protects from interleukin-10 deficiency-induced colitis in mice by suppressing T-lymphocyte interferon-γ production. Goettel JA, Scott Algood HM, Olivares-Villagómez D, Washington MK, Chaturvedi R, Wilson KT, Van Kaer L, Polk DB (2011) Gastroenterology 140: 265-74 Cdc42 coordinates proliferation, polarity, migration, and differentiation of small intestinal epithelial cells in mice. Melendez J, Liu M, Sampson L, Akunuru S, Han X, Vallance J, Witte D, Shroyer N, Zheng Y (2013) Gastroenterology 145: 808-19 The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturation. Capoccia BJ, Jin RU, Kong YY, Peek RM, Fassan M, Rugge M, Mills JC (2013) J Clin Invest 123: 1475-91 CSF-1 signaling mediates recovery from acute kidney injury. Zhang MZ, Yao B, Yang S, Jiang L, Wang S, Fan X, Yin H, Wong K, Miyazawa T, Chen J, Chang I, Singh A, Harris RC (2012) J Clin Invest 122: 4519-32 IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation. Yamaoka-Tojo M, Ushio-Fukai M, Hilenski L, Dikalov SI, Chen YE, Tojo T, Fukai T, Fujimoto M, Patrushev NA, Wang N, Kontos CD, Bloom GS, Alexander RW (2004) Circ Res 95: 276-83 Epicardial/Mesothelial cell line retains vasculogenic potential of embryonic epicardium. Wada AM, Smith TK, Osler ME, Reese DE, Bader DM (2003) Circ Res 92: 525-31 RNA localization and polarity: from A(PC) to Z(BP). Mili S, Macara IG (2009) Trends Cell Biol 19: 156-64 Epithelial organization, cell polarity and tumorigenesis. McCaffrey LM, Macara IG (2011) Trends Cell Biol 21: 727-35 Asymmetric focal adhesion disassembly in motile cells. Broussard JA, Webb DJ, Kaverina I (2008) Curr Opin Cell Biol 20: 85-90 Mechanisms of polarity protein expression control. Ahmed SM, Macara IG (2016) Curr Opin Cell Biol 42: 38-45 Recycling endosomes. Goldenring JR (2015) Curr Opin Cell Biol 35: 117-22 Functional design in the actin cytoskeleton. Small JV, Rottner K, Kaverina I (1999) Curr Opin Cell Biol 11: 54-60 Microtubules meet substrate adhesions to arrange cell polarity. Small JV, Kaverina I (2003) Curr Opin Cell Biol 15: 40-7 A small part of myosin IIB takes on a big role in cell polarity. Fenix AM, Burnette DT (2015) J Cell Biol 209: 11-2 Apical enrichment of human EGF precursor in Madin-Darby canine kidney cells involves preferential basolateral ectodomain cleavage sensitive to a metalloprotease inhibitor. Dempsey PJ, Meise KS, Yoshitake Y, Nishikawa K, Coffey RJ (1997) J Cell Biol 138: 747-58 Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation. Qin Y, Meisen WH, Hao Y, Macara IG (2010) J Cell Biol 189: 661-9 Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering. El-Husseini AE, Craven SE, Chetkovich DM, Firestein BL, Schnell E, Aoki C, Bredt DS (2000) J Cell Biol 148: 159-72 UNC-45a promotes myosin folding and stress fiber assembly. Lehtimäki JI, Fenix AM, Kotila TM, Balistreri G, Paavolainen L, Varjosalo M, Burnette DT, Lappalainen P (2017) J Cell Biol 216: 4053-4072 The enterocyte microvillus is a vesicle-generating organelle. McConnell RE, Higginbotham JN, Shifrin DA, Tabb DL, Coffey RJ, Tyska MJ (2009) J Cell Biol 185: 1285-98 Microtubule targeting of substrate contacts promotes their relaxation and dissociation. Kaverina I, Krylyshkina O, Small JV (1999) J Cell Biol 146: 1033-44 Vinculin controls talin engagement with the actomyosin machinery. Atherton P, Stutchbury B, Wang DY, Jethwa D, Tsang R, Meiler-Rodriguez E, Wang P, Bate N, Zent R, Barsukov IL, Goult BT, Critchley DR, Ballestrem C (2015) Nat Commun 6: 10038
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