Shu Xu
Last active: 4/14/2017

  1. nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2. Neumann W, Xu S, Sárosi MB, Scholz MS, Crews BC, Ghebreselasie K, Banerjee S, Marnett LJ, Hey-Hawkins E (2016) ChemMedChem 11(2): 175-8
    › Primary publication · 26088701 (PubMed) · PMC4900168 (PubMed Central)
  2. Covalent Modification of CDK2 by 4-Hydroxynonenal as a Mechanism of Inhibition of Cell Cycle Progression. Camarillo JM, Rose KL, Galligan JJ, Xu S, Marnett LJ (2016) Chem Res Toxicol 29(3): 323-32
    › Primary publication · 26910110 (PubMed) · PMC5058421 (PubMed Central)
  3. Conservative Secondary Shell Substitution In Cyclooxygenase-2 Reduces Inhibition by Indomethacin Amides and Esters via Altered Enzyme Dynamics. Konkle ME, Blobaum AL, Moth CW, Prusakiewicz JJ, Xu S, Ghebreselasie K, Akingbade D, Jacobs AT, Rouzer CA, Lybrand TP, Marnett LJ (2016) Biochemistry 55(2): 348-59
    › Primary publication · 26704937 (PubMed) · PMC4721528 (PubMed Central)
  4. Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors. Uddin MJ, Crews BC, Xu S, Ghebreselasie K, Daniel CK, Kingsley PJ, Banerjee S, Marnett LJ (2016) ACS Chem Biol 11(11): 3052-3060
    › Primary publication · 27588346 (PubMed) · PMC5289892 (PubMed Central)
  5. Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe. Uddin MJ, Crews BC, Ghebreselasie K, Daniel CK, Kingsley PJ, Xu S, Marnett LJ (2015) J Biomed Opt 20(5): 50502
    › Primary publication · 25970082 (PubMed) · PMC4430360 (PubMed Central)
  6. Action at a distance: mutations of peripheral residues transform rapid reversible inhibitors to slow, tight binders of cyclooxygenase-2. Blobaum AL, Xu S, Rowlinson SW, Duggan KC, Banerjee S, Kudalkar SN, Birmingham WR, Ghebreselasie K, Marnett LJ (2015) J Biol Chem 290(20): 12793-803
    › Primary publication · 25825493 (PubMed) · PMC4432295 (PubMed Central)
  7. 13-Methylarachidonic acid is a positive allosteric modulator of endocannabinoid oxygenation by cyclooxygenase. Kudalkar SN, Nikas SP, Kingsley PJ, Xu S, Galligan JJ, Rouzer CA, Banerjee S, Ji L, Eno MR, Makriyannis A, Marnett LJ (2015) J Biol Chem 290(12): 7897-909
    › Primary publication · 25648895 (PubMed) · PMC4367288 (PubMed Central)
  8. Oxicams bind in a novel mode to the cyclooxygenase active site via a two-water-mediated H-bonding Network. Xu S, Hermanson DJ, Banerjee S, Ghebreselasie K, Clayton GM, Garavito RM, Marnett LJ (2014) J Biol Chem 289(10): 6799-6808
    › Primary publication · 24425867 (PubMed) · PMC3945341 (PubMed Central)
  9. Oxicams, a class of nonsteroidal anti-inflammatory drugs and beyond. Xu S, Rouzer CA, Marnett LJ (2014) IUBMB Life 66(12): 803-11
    › Primary publication · 25537198 (PubMed) · PMC5300000 (PubMed Central)
  10. Exploring the molecular determinants of substrate-selective inhibition of cyclooxygenase-2 by lumiracoxib. Windsor MA, Valk PL, Xu S, Banerjee S, Marnett LJ (2013) Bioorg Med Chem Lett 23(21): 5860-4
    › Primary publication · 24060487 (PubMed) · PMC3857387 (PubMed Central)