Benjamin Spiller
Last active: 4/10/2019

  1. A neutralizing antibody that blocks delivery of the enzymatic cargo of toxin TcdB into host cells. Kroh HK, Chandrasekaran R, Zhang Z, Rosenthal K, Woods R, Jin X, Nyborg AC, Rainey GJ, Warrener P, Melnyk RA, Spiller BW, Lacy DB (2018) J Biol Chem 293(3): 941-952
    › Primary publication · 29180448 (PubMed) · PMC5777265 (PubMed Central)
  2. Use of a neutralizing antibody helps identify structural features critical for binding of toxin TcdA to the host cell surface. Kroh HK, Chandrasekaran R, Rosenthal K, Woods R, Jin X, Ohi MD, Nyborg AC, Rainey GJ, Warrener P, Spiller BW, Lacy DB (2017) J Biol Chem 292(35): 14401-14412
    › Primary publication · 28705932 (PubMed) · PMC5582835 (PubMed Central)
  3. The three Type 2A protein phosphatases, PP2Ac, PP4c and PP6c, are differentially regulated by Alpha4. LeNoue-Newton ML, Wadzinski BE, Spiller BW (2016) Biochem Biophys Res Commun 475(1): 64-9
    › Primary publication · 27169767 (PubMed) · PMC6484841 (PubMed Central)
  4. Crystal structure of toxin A. Chumbler NM, Rutherford SA, Zhang Z, Farrow MA, Lisher JP, Farquhar E, Giedroc DP, Spiller BW, Melnyk RA, Lacy DB (2016) Nat Microbiol
    › Primary publication · 27512603 (PubMed)
  5. Crystal structure of Clostridium difficile toxin A. Chumbler NM, Rutherford SA, Zhang Z, Farrow MA, Lisher JP, Farquhar E, Giedroc DP, Spiller BW, Melnyk RA, Lacy DB (2016) Nat Microbiol : 15002
    › Primary publication · 27571750 (PubMed) · PMC4976693 (PubMed Central)
  6. A Nonoligomerizing Mutant Form of Helicobacter pylori VacA Allows Structural Analysis of the p33 Domain. González-Rivera C, Campbell AM, Rutherford SA, Pyburn TM, Foegeding NJ, Barke TL, Spiller BW, McClain MS, Ohi MD, Lacy DB, Cover TL (2016) Infect Immun 84(9): 2662-70
    › Primary publication · 27382020 (PubMed) · PMC4995914 (PubMed Central)
  7. Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites. Winarski KL, Thornburg NJ, Yu Y, Sapparapu G, Crowe JE, Spiller BW (2015) Proc Natl Acad Sci U S A 112(30): 9346-51
    › Primary publication · 26170302 (PubMed) · PMC4522792 (PubMed Central)
  8. Short forms of Ste20-related proline/alanine-rich kinase (SPAK) in the kidney are created by aspartyl aminopeptidase (Dnpep)-mediated proteolytic cleavage. Markadieu N, Rios K, Spiller BW, McDonald WH, Welling PA, Delpire E (2014) J Biol Chem 289(42): 29273-84
    › Primary publication · 25164821 (PubMed) · PMC4200278 (PubMed Central)
  9. Differential accessibility of a rotavirus VP6 epitope in trimers comprising type I, II, or III channels as revealed by binding of a human rotavirus VP6-specific antibody. Aiyegbo MS, Eli IM, Spiller BW, Williams DR, Kim R, Lee DE, Liu T, Li S, Stewart PL, Crowe JE (2014) J Virol 88(1): 469-76
    › Primary publication · 24155406 (PubMed) · PMC3911710 (PubMed Central)
  10. A gatekeeper chaperone complex directs translocator secretion during type three secretion. Archuleta TL, Spiller BW (2014) PLoS Pathog 10(11): e1004498
    › Primary publication · 25375170 (PubMed) · PMC4222845 (PubMed Central)