Benjamin Spiller
Last active: 4/10/2019

  1. Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore. Aiyegbo MS, Sapparapu G, Spiller BW, Eli IM, Williams DR, Kim R, Lee DE, Liu T, Li S, Woods VL, Nannemann DP, Meiler J, Stewart PL, Crowe JE (2013) PLoS One 8(5): e61101
    › Primary publication · 23671563 (PubMed) · PMC3650007 (PubMed Central)
  2. Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses. Thornburg NJ, Nannemann DP, Blum DL, Belser JA, Tumpey TM, Deshpande S, Fritz GA, Sapparapu G, Krause JC, Lee JH, Ward AB, Lee DE, Li S, Winarski KL, Spiller BW, Meiler J, Crowe JE (2013) J Clin Invest 123(10): 4405-9
    › Primary publication · 23999429 (PubMed) · PMC3784541 (PubMed Central)
  3. Structural determinants of Clostridium difficile toxin A glucosyltransferase activity. Pruitt RN, Chumbler NM, Rutherford SA, Farrow MA, Friedman DB, Spiller B, Lacy DB (2012) J Biol Chem 287(11): 8013-20
    › Primary publication · 22267739 (PubMed) · PMC3318759 (PubMed Central)
  4. Monoubiquitination promotes calpain cleavage of the protein phosphatase 2A (PP2A) regulatory subunit α4, altering PP2A stability and microtubule-associated protein phosphorylation. Watkins GR, Wang N, Mazalouskas MD, Gomez RJ, Guthrie CR, Kraemer BC, Schweiger S, Spiller BW, Wadzinski BE (2012) J Biol Chem 287(29): 24207-15
    › Primary publication · 22613722 (PubMed) · PMC3397847 (PubMed Central)
  5. Crystal structure of an activated variant of small heat shock protein Hsp16.5. McHaourab HS, Lin YL, Spiller BW (2012) Biochemistry 51(25): 5105-12
    › Primary publication · 22670769 (PubMed) · PMC3384710 (PubMed Central)
  6. The E3 ubiquitin ligase- and protein phosphatase 2A (PP2A)-binding domains of the Alpha4 protein are both required for Alpha4 to inhibit PP2A degradation. LeNoue-Newton M, Watkins GR, Zou P, Germane KL, McCorvey LR, Wadzinski BE, Spiller BW (2011) J Biol Chem 286(20): 17665-71
    › Primary publication · 21454489 (PubMed) · PMC3093842 (PubMed Central)
  7. The Chlamydia effector chlamydial outer protein N (CopN) sequesters tubulin and prevents microtubule assembly. Archuleta TL, Du Y, English CA, Lory S, Lesser C, Ohi MD, Ohi R, Spiller BW (2011) J Biol Chem 286(39): 33992-8
    › Primary publication · 21841198 (PubMed) · PMC3190796 (PubMed Central)
  8. Structural and functional studies indicate that the EPEC effector, EspG, directly binds p21-activated kinase. Germane KL, Spiller BW (2011) Biochemistry 50(6): 917-9
    › Primary publication · 21235237 (PubMed) · PMC3040069 (PubMed Central)
  9. Crystal structure of arrestin-3 reveals the basis of the difference in receptor binding between two non-visual subtypes. Zhan X, Gimenez LE, Gurevich VV, Spiller BW (2011) J Mol Biol 406(3): 467-78
    › Primary publication · 21215759 (PubMed) · PMC3034793 (PubMed Central)
  10. A single mutation in arrestin-2 prevents ERK1/2 activation by reducing c-Raf1 binding. Coffa S, Breitman M, Spiller BW, Gurevich VV (2011) Biochemistry 50(32): 6951-8
    › Primary publication · 21732673 (PubMed) · PMC3153575 (PubMed Central)