1. Vitamin E does not prevent Western diet-induced NASH progression and increases metabolic flux dysregulation in mice. Hasenour CM, Kennedy AJ, Bednarski T, Trenary IA, Eudy BJ, da Silva RP, Boyd KL, Young JD (2020) J Lipid Res 61(5): 707-721
    › Primary publication · 32086244 (PubMed) · PMC7193953 (PubMed Central)
  2. Tracing metabolic flux through time and space with isotope labeling experiments. Allen DK, Young JD (2020) Curr Opin Biotechnol : 92-100
    › Primary publication · 31864070 (PubMed) · PMC7302994 (PubMed Central)
  3. Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver. Deja S, Fu X, Fletcher JA, Kucejova B, Browning JD, Young JD, Burgess SC (2020) Metab Eng : 1-14
    › Primary publication · 31891762 (PubMed) · PMC7108978 (PubMed Central)
  4. Genome-Scale Model-Based Identification of Metabolite Indicators for Early Detection of Kidney Toxicity. Pannala VR, Vinnakota KC, Estes SK, Trenary I, OňąBrien TP, Printz RL, Papin JA, Reifman J, Oyama T, Shiota M, Young JD, Wallqvist A (2020) Toxicol Sci 173(2): 293-312
    › Primary publication · 31722432 (PubMed) · PMC8000070 (PubMed Central)
  5. Applications of stable isotope-based metabolomics and fluxomics toward synthetic biology of cyanobacteria. Babele PK, Young JD (2020) Wiley Interdiscip Rev Syst Biol Med 12(3): e1472
    › Primary publication · 31816180 (PubMed)
  6. Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat. Vinnakota KC, Pannala VR, Wall ML, Rahim M, Estes SK, Trenary I, O'Brien TP, Printz RL, Reifman J, Shiota M, Young JD, Wallqvist A (2019) Front Physiol : 161
    › Primary publication · 30881311 (PubMed) · PMC6405515 (PubMed Central)
  7. Mechanistic identification of biofluid metabolite changes as markers of acetaminophen-induced liver toxicity in rats. Pannala VR, Vinnakota KC, Rawls KD, Estes SK, O'Brien TP, Printz RL, Papin JA, Reifman J, Shiota M, Young JD, Wallqvist A (2019) Toxicol Appl Pharmacol : 19-32
    › Primary publication · 30974156 (PubMed) · PMC6599641 (PubMed Central)
  8. Glutamate-oxaloacetate transaminase activity promotes palmitate lipotoxicity in rat hepatocytes by enhancing anaplerosis and citric acid cycle flux. Egnatchik RA, Leamy AK, Sacco SA, Cheah YE, Shiota M, Young JD (2019) J Biol Chem 294(9): 3081-3090
    › Primary publication · 30563841 (PubMed) · PMC6398133 (PubMed Central)
  9. xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression. Ji X, Qian J, Rahman SMJ, Siska PJ, Zou Y, Harris BK, Hoeksema MD, Trenary IA, Heidi C, Eisenberg R, Rathmell JC, Young JD, Massion PP (2018) Oncogene 37(36): 5007-5019
    › Primary publication · 29789716 (PubMed) · PMC6127081 (PubMed Central)
  10. The TLR4 Agonist Monophosphoryl Lipid A Drives Broad Resistance to Infection via Dynamic Reprogramming of Macrophage Metabolism. Fensterheim BA, Young JD, Luan L, Kleinbard RR, Stothers CL, Patil NK, McAtee-Pereira AG, Guo Y, Trenary I, Hernandez A, Fults JB, Williams DL, Sherwood ER, Bohannon JK (2018) J Immunol 200(11): 3777-3789
    › Primary publication · 29686054 (PubMed) · PMC5964009 (PubMed Central)