Robert Macdonald
Last active: 4/6/2017

  1. GABRB3 mutation, G32R, associated with childhood absence epilepsy alters α1β3γ2L γ-aminobutyric acid type A (GABAA) receptor expression and channel gating. Gurba KN, Hernandez CC, Hu N, Macdonald RL (2012) J Biol Chem 287(15): 12083-97
    › Primary publication · 22303015 (PubMed) · PMC3320954 (PubMed Central)
  2. The GABRA6 mutation, R46W, associated with childhood absence epilepsy, alters 6β22 and 6β2 GABA(A) receptor channel gating and expression. Hernandez CC, Gurba KN, Hu N, Macdonald RL (2011) J Physiol 589(Pt 23): 5857-78
    › Primary publication · 21930603 (PubMed) · PMC3249055 (PubMed Central)
  3. Slow degradation and aggregation in vitro of mutant GABAA receptor gamma2(Q351X) subunits associated with epilepsy. Kang JQ, Shen W, Lee M, Gallagher MJ, Macdonald RL (2010) J Neurosci 30(41): 13895-905
    › Primary publication · 20943930 (PubMed) · PMC2976503 (PubMed Central)
  4. Mutations in GABAA receptor subunits associated with genetic epilepsies. Macdonald RL, Kang JQ, Gallagher MJ (2010) J Physiol 588(Pt 11): 1861-9
    › Primary publication · 20308251 (PubMed) · PMC2901974 (PubMed Central)
  5. Glycosylation of {beta}2 subunits regulates GABAA receptor biogenesis and channel gating. Lo WY, Lagrange AH, Hernandez CC, Harrison R, Dell A, Haslam SM, Sheehan JH, Macdonald RL (2010) J Biol Chem 285(41): 31348-61
    › Primary publication · 20639197 (PubMed) · PMC2951209 (PubMed Central)
  6. Barbiturates require the N terminus and first transmembrane domain of the delta subunit for enhancement of alpha1beta3delta GABAA receptor currents. Feng HJ, Macdonald RL (2010) J Biol Chem 285(31): 23614-21
    › Primary publication · 20525684 (PubMed) · PMC2911329 (PubMed Central)