Michael Waterman
Faculty Member
Last active: 2/12/2015

  1. Electron transport pathway for a Streptomyces cytochrome P450: cytochrome P450 105D5-catalyzed fatty acid hydroxylation in Streptomyces coelicolor A3(2). Chun YJ, Shimada T, Sanchez-Ponce R, Martin MV, Lei L, Zhao B, Kelly SL, Waterman MR, Lamb DC, Guengerich FP (2007) J Biol Chem 282(24): 17486-500
    › Primary publication · 17446171 (PubMed)
  2. Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2. Zhao B, Lamb DC, Lei L, Kelly SL, Yuan H, Hachey DL, Waterman MR (2007) Biochemistry 46(30): 8725-33
    › Primary publication · 17614370 (PubMed)
  3. Cytochromes P450 and drug discovery. Lamb DC, Waterman MR, Kelly SL, Guengerich FP (2007) Curr Opin Biotechnol 18(6): 504-12
    › Primary publication · 18006294 (PubMed)
  4. Conformational dynamics in the F/G segment of CYP51 from Mycobacterium tuberculosis monitored by FRET. Lepesheva GI, Seliskar M, Knutson CG, Stourman NV, Rozman D, Waterman MR (2007) Arch Biochem Biophys 464(2): 221-7
    › Primary publication · 17585868 (PubMed) · PMC3042880 (PubMed Central)
  5. Understanding electron transport systems of Streptomyces cytochrome P450. Chun YJ, Shimada T, Waterman MR, Guengerich FP (2006) Biochem Soc Trans 34(Pt 6): 1183-5
    › Primary publication · 17073781 (PubMed)
  6. The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae. Sherman DH, Li S, Yermalitskaya LV, Kim Y, Smith JA, Waterman MR, Podust LM (2006) J Biol Chem 281(36): 26289-97
    › Primary publication · 16825192 (PubMed) · PMC2939096 (PubMed Central)
  7. The cytochrome P450 gene family CYP157 does not contain EXXR in the K-helix reducing the absolute conserved P450 residues to a single cysteine. Rupasinghe S, Schuler MA, Kagawa N, Yuan H, Lei L, Zhao B, Kelly SL, Waterman MR, Lamb DC (2006) FEBS Lett 580(27): 6338-42
    › Primary publication · 17092500 (PubMed)
  8. Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel. Nakagawa K, Holla VR, Wei Y, Wang WH, Gatica A, Wei S, Mei S, Miller CM, Cha DR, Price E, Zent R, Pozzi A, Breyer MD, Guan Y, Falck JR, Waterman MR, Capdevila JH (2006) J Clin Invest 116(6): 1696-702
    › Primary publication · 16691295 (PubMed) · PMC1459070 (PubMed Central)
  9. Raman evidence for specific substrate-induced structural changes in the heme pocket of human cytochrome P450 aromatase during the three consecutive oxygen activation steps. Tosha T, Kagawa N, Ohta T, Yoshioka S, Waterman MR, Kitagawa T (2006) Biochemistry 45(17): 5631-40
    › Primary publication · 16634644 (PubMed)
  10. Purification and characterization of bovine steroid 21-hydroxylase (P450c21) efficiently expressed in Escherichia coli. Arase M, Waterman MR, Kagawa N (2006) Biochem Biophys Res Commun 344(1): 400-5
    › Primary publication · 16597434 (PubMed)