Michael Waterman
Faculty Member
Last active: 2/12/2015

  1. Cytochrome p450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2). Lamb DC, Ikeda H, Nelson DR, Ishikawa J, Skaug T, Jackson C, Omura S, Waterman MR, Kelly SL (2003) Biochem Biophys Res Commun 307(3): 610-9
    › Primary publication · 12893267 (PubMed)
  2. Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function. Lepesheva GI, Virus C, Waterman MR (2003) Biochemistry 42(30): 9091-101
    › Primary publication · 12885242 (PubMed)
  3. Transcriptional activation of human CYP17 in H295R adrenocortical cells depends on complex formation among p54(nrb)/NonO, protein-associated splicing factor, and SF-1, a complex that also participates in repression of transcription. Sewer MB, Nguyen VQ, Huang CJ, Tucker PW, Kagawa N, Waterman MR (2002) Endocrinology 143(4): 1280-90
    › Primary publication · 11897684 (PubMed)
  4. Substrate recognition sites in 14alpha-sterol demethylase from comparative analysis of amino acid sequences and X-ray structure of Mycobacterium tuberculosis CYP51. Podust LM, Stojan J, Poulos TL, Waterman MR (2001) J Inorg Biochem 87(4): 227-35
    › Primary publication · 11744060 (PubMed)
  5. Structural requirements for substrate recognition of Mycobacterium tuberculosis 14 alpha-demethylase: implications for sterol biosynthesis. Bellamine A, Mangla AT, Dennis AL, Nes WD, Waterman MR (2001) J Lipid Res 42(1): 128-36
    › Primary publication · 11160374 (PubMed)
  6. Microsomal p450s use specific proline-rich sequences for efficient folding, but not for maintenance of the folded structure. Kusano K, Sakaguchi M, Kagawa N, Waterman MR, Omura T (2001) J Biochem 129(2): 259-69
    › Primary publication · 11173528 (PubMed)
  7. Insights into the transcriptional regulation of steroidogenic enzymes and StAR. Sewer MB, Waterman MR (2001) Rev Endocr Metab Disord 2(3): 269-74
    › Primary publication · 11705132 (PubMed)
  8. Importance of a proline-rich sequence in the amino-terminal region for correct folding of mitochondrial and soluble microbial p450s. Kusano K, Kagawa N, Sakaguchi M, Omura T, Waterman MR (2001) J Biochem 129(2): 271-7
    › Primary publication · 11173529 (PubMed)
  9. Folding requirements are different between sterol 14alpha-demethylase (CYP51) from Mycobacterium tuberculosis and human or fungal orthologs. Lepesheva GI, Podust LM, Bellamine A, Waterman MR (2001) J Biol Chem 276(30): 28413-20
    › Primary publication · 11373285 (PubMed)
  10. Evolutionarily divergent electron donor proteins interact with P450MT2 through the same helical domain but different contact points. Anandatheerthavarada HK, Amuthan G, Biswas G, Robin MA, Murali R, Waterman MR, Avadhani NG (2001) EMBO J 20(10): 2394-403
    › Primary publication · 11350928 (PubMed) · PMC125462 (PubMed Central)