Michael Waterman
Faculty Member
Last active: 2/12/2015

  1. Structural complex of sterol 14α-demethylase (CYP51) with 14α-methylenecyclopropyl-Delta7-24, 25-dihydrolanosterol. Hargrove TY, Wawrzak Z, Liu J, Waterman MR, Nes WD, Lepesheva GI (2012) J Lipid Res 53(2): 311-20
    › Primary publication · 22135275 (PubMed) · PMC3269163 (PubMed Central)
  2. Structural analysis of cytochrome P450 105N1 involved in the biosynthesis of the zincophore, coelibactin. Zhao B, Moody SC, Hider RC, Lei L, Kelly SL, Waterman MR, Lamb DC (2012) Int J Mol Sci 13(7): 8500-13
    › Primary publication · 22942716 (PubMed) · PMC3430247 (PubMed Central)
  3. Organocatalytic, enantioselective synthesis of VNI: a robust therapeutic development platform for Chagas, a neglected tropical disease. Dobish MC, Villalta F, Waterman MR, Lepesheva GI, Johnston JN (2012) Org Lett 14(24): 6322-5
    › Primary publication · 23214987 (PubMed) · PMC3528807 (PubMed Central)
  4. Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms. Nes CR, Singha UK, Liu J, Ganapathy K, Villalta F, Waterman MR, Lepesheva GI, Chaudhuri M, Nes WD (2012) Biochem J 443(1): 267-77
    › Primary publication · 22176028 (PubMed) · PMC3491665 (PubMed Central)
  5. Investigating conservation of the albaflavenone biosynthetic pathway and CYP170 bifunctionality in streptomycetes. Moody SC, Zhao B, Lei L, Nelson DR, Mullins JG, Waterman MR, Kelly SL, Lamb DC (2012) FEBS J 279(9): 1640-9
    › Primary publication · 22151149 (PubMed)
  6. Targeting Trypanosoma cruzi sterol 14α-demethylase (CYP51). Lepesheva GI, Villalta F, Waterman MR (2011) Adv Parasitol : 65-87
    › Primary publication · 21820552 (PubMed) · PMC3488290 (PubMed Central)
  7. Substrate preferences and catalytic parameters determined by structural characteristics of sterol 14alpha-demethylase (CYP51) from Leishmania infantum. Hargrove TY, Wawrzak Z, Liu J, Nes WD, Waterman MR, Lepesheva GI (2011) J Biol Chem 286(30): 26838-48
    › Primary publication · 21632531 (PubMed) · PMC3143644 (PubMed Central)
  8. Structural basis for conservation in the CYP51 family. Lepesheva GI, Waterman MR (2011) Biochim Biophys Acta 1814(1): 88-93
    › Primary publication · 20547249 (PubMed) · PMC2962772 (PubMed Central)
  9. Sterol 14alpha-demethylase (CYP51) as a therapeutic target for human trypanosomiasis and leishmaniasis. Lepesheva GI, Waterman MR (2011) Curr Top Med Chem 11(16): 2060-71
    › Primary publication · 21619513 (PubMed) · PMC3391166 (PubMed Central)
  10. Moonlighting cytochrome P450 monooxygenases. Zhao B, Waterman MR (2011) IUBMB Life 63(7): 473-7
    › Primary publication · 21698750 (PubMed) · PMC3122146 (PubMed Central)