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Michael Waterman
Faculty Member
Last active: 2/12/2015

  1. Structural insights into inhibition of sterol 14alpha-demethylase in the human pathogen Trypanosoma cruzi. Lepesheva GI, Hargrove TY, Anderson S, Kleshchenko Y, Furtak V, Wawrzak Z, Villalta F, Waterman MR (2010) J Biol Chem 285(33): 25582-90
    › Primary publication · 20530488 (PubMed) · PMC2919122 (PubMed Central)
  2. Streptomyces coelicolor A3(2) CYP102 protein, a novel fatty acid hydroxylase encoded as a heme domain without an N-terminal redox partner. Lamb DC, Lei L, Zhao B, Yuan H, Jackson CJ, Warrilow AG, Skaug T, Dyson PJ, Dawson ES, Kelly SL, Hachey DL, Waterman MR (2010) Appl Environ Microbiol 76(6): 1975-80
    › Primary publication · 20097805 (PubMed) · PMC2838009 (PubMed Central)
  3. Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections. Lepesheva GI, Park HW, Hargrove TY, Vanhollebeke B, Wawrzak Z, Harp JM, Sundaramoorthy M, Nes WD, Pays E, Chaudhuri M, Villalta F, Waterman MR (2010) J Biol Chem 285(3): 1773-80
    › Primary publication · 19923211 (PubMed) · PMC2804335 (PubMed Central)
  4. The first virally encoded cytochrome p450. Lamb DC, Lei L, Warrilow AG, Lepesheva GI, Mullins JG, Waterman MR, Kelly SL (2009) J Virol 83(16): 8266-9
    › Primary publication · 19515774 (PubMed) · PMC2715754 (PubMed Central)
  5. Structural biology: Anticancer drug target pictured. Waterman MR (2009) Nature 457(7226): 159-60
    › Primary publication · 19129840 (PubMed)
  6. Indomethacin amides as a novel molecular scaffold for targeting Trypanosoma cruzi sterol 14alpha-demethylase. Konkle ME, Hargrove TY, Kleshchenko YY, von Kries JP, Ridenour W, Uddin MJ, Caprioli RM, Marnett LJ, Nes WD, Villalta F, Waterman MR, Lepesheva GI (2009) J Med Chem 52(9): 2846-53
    › Primary publication · 19354253 (PubMed) · PMC2744100 (PubMed Central)
  7. Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site. Zhao B, Lei L, Vassylyev DG, Lin X, Cane DE, Kelly SL, Yuan H, Lamb DC, Waterman MR (2009) J Biol Chem 284(52): 36711-36719
    › Primary publication · 19858213 (PubMed) · PMC2794785 (PubMed Central)
  8. The T8590C polymorphism of CYP4A11 and 20-hydroxyeicosatetraenoic acid in essential hypertension. Laffer CL, Gainer JV, Waterman MR, Capdevila JH, Laniado-Schwartzman M, Nasjletti A, Brown NJ, Elijovich F (2008) Hypertension 51(3): 767-72
    › Primary publication · 18227405 (PubMed) · PMC2365894 (PubMed Central)
  9. The ferrous-oxy complex of human aromatase. Grinkova YV, Denisov IG, Waterman MR, Arase M, Kagawa N, Sligar SG (2008) Biochem Biophys Res Commun 372(2): 379-82
    › Primary publication · 18482580 (PubMed) · PMC2478517 (PubMed Central)
  10. Purification and functional characterization of human 11beta hydroxylase expressed in Escherichia coli. Zöllner A, Kagawa N, Waterman MR, Nonaka Y, Takio K, Shiro Y, Hannemann F, Bernhardt R (2008) FEBS J 275(4): 799-810
    › Primary publication · 18215163 (PubMed)