Michael Waterman
Faculty Member
Last active: 2/12/2015

  1. Mechanistic analysis of a multiple product sterol methyltransferase implicated in ergosterol biosynthesis in Trypanosoma brucei. Zhou W, Lepesheva GI, Waterman MR, Nes WD (2006) J Biol Chem 281(10): 6290-6
    › Primary publication · 16414960 (PubMed)
  2. Ligand-assisted inhibition in cytochrome P450 158A2 from Streptomyces coelicolor A3(2). Zhao B, Waterman MR, Isin EM, Sundaramoorthy M, Podust LM (2006) Biochemistry 45(24): 7493-500
    › Primary publication · 16768445 (PubMed)
  3. Exploiting Streptomyces coelicolor A3(2) P450s as a model for application in drug discovery. Lamb DC, Guengerich FP, Kelly SL, Waterman MR (2006) Expert Opin Drug Metab Toxicol 2(1): 27-40
    › Primary publication · 16863466 (PubMed)
  4. Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions. McLean KJ, Warman AJ, Seward HE, Marshall KR, Girvan HM, Cheesman MR, Waterman MR, Munro AW (2006) Biochemistry 45(27): 8427-43
    › Primary publication · 16819841 (PubMed)
  5. Biodiversity of CYP51 in trypanosomes. Lepesheva GI, Hargrove TY, Ott RD, Nes WD, Waterman MR (2006) Biochem Soc Trans 34(Pt 6): 1161-4
    › Primary publication · 17073776 (PubMed)
  6. A second FMN binding site in yeast NADPH-cytochrome P450 reductase suggests a mechanism of electron transfer by diflavin reductases. Lamb DC, Kim Y, Yermalitskaya LV, Yermalitsky VN, Lepesheva GI, Kelly SL, Waterman MR, Podust LM (2006) Structure 14(1): 51-61
    › Primary publication · 16407065 (PubMed)
  7. Tetracycline protects myocardium against ischemic injury. Kagawa N, Senbonmatsu TA, Satoh K, Ichihara K, Yamagata N, Hatano O, Saito T, Nguyen VQ, Waterman MR, Price E, Atkinson JB, Inagami T (2005) Front Biosci : 608-19
    › Primary publication · 15569603 (PubMed)
  8. Structural diversities of active site in clinical azole-bound forms between sterol 14alpha-demethylases (CYP51s) from human and Mycobacterium tuberculosis. Matsuura K, Yoshioka S, Tosha T, Hori H, Ishimori K, Kitagawa T, Morishima I, Kagawa N, Waterman MR (2005) J Biol Chem 280(10): 9088-96
    › Primary publication · 15611056 (PubMed)
  9. Sterol 14 alpha-demethylase, an abundant and essential mixed-function oxidase. Waterman MR, Lepesheva GI (2005) Biochem Biophys Res Commun 338(1): 418-22
    › Primary publication · 16153595 (PubMed)
  10. Role of active site water molecules and substrate hydroxyl groups in oxygen activation by cytochrome P450 158A2: a new mechanism of proton transfer. Zhao B, Guengerich FP, Voehler M, Waterman MR (2005) J Biol Chem 280(51): 42188-97
    › Primary publication · 16239228 (PubMed)