Carmelo Rizzo
Faculty Member
Last active: 1/7/2016

  1. Structure-function relationships in miscoding by Sulfolobus solfataricus DNA polymerase Dpo4: guanine N2,N2-dimethyl substitution produces inactive and miscoding polymerase complexes. Zhang H, Eoff RL, Kozekov ID, Rizzo CJ, Egli M, Guengerich FP (2009) J Biol Chem 284(26): 17687-99
    › Primary publication · 19542237 (PubMed) · PMC2719408 (PubMed Central)
  2. Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct. Eoff RL, Stafford JB, Szekely J, Rizzo CJ, Egli M, Guengerich FP, Marnett LJ (2009) Biochemistry 48(30): 7079-88
    › Primary publication · 19492857 (PubMed) · PMC2717710 (PubMed Central)
  3. Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases. Zhang H, Bren U, Kozekov ID, Rizzo CJ, Stec DF, Guengerich FP (2009) J Mol Biol 392(2): 251-69
    › Primary publication · 19607842 (PubMed) · PMC2755575 (PubMed Central)
  4. Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2'-deoxyguanosine adduct in the 5'-CpG-3' DNA sequence. Huang H, Kim HY, Kozekov ID, Cho YJ, Wang H, Kozekova A, Harris TM, Rizzo CJ, Stone MP (2009) J Am Chem Soc 131(24): 8416-24
    › Primary publication · 19530727 (PubMed) · PMC2753404 (PubMed Central)
  5. Replication past the N5-methyl-formamidopyrimidine lesion of deoxyguanosine by DNA polymerases and an improved procedure for sequence analysis of in vitro bypass products by mass spectrometry. Christov PP, Angel KC, Guengerich FP, Rizzo CJ (2009) Chem Res Toxicol 22(6): 1086-95
    › Primary publication · 19397282 (PubMed) · PMC2754150 (PubMed Central)
  6. Oxidation and glycolytic cleavage of etheno and propano DNA base adducts. Knutson CG, Rubinson EH, Akingbade D, Anderson CS, Stec DF, Petrova KV, Kozekov ID, Guengerich FP, Rizzo CJ, Marnett LJ (2009) Biochemistry 48(4): 800-9
    › Primary publication · 19132922 (PubMed) · PMC2975463 (PubMed Central)
  7. Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) 1,N(2)-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA. Huang H, Wang H, Lloyd RS, Rizzo CJ, Stone MP (2009) Chem Res Toxicol 22(1): 187-200
    › Primary publication · 19053179 (PubMed) · PMC2645987 (PubMed Central)
  8. Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal. Minko IG, Kozekov ID, Harris TM, Rizzo CJ, Lloyd RS, Stone MP (2009) Chem Res Toxicol 22(5): 759-78
    › Primary publication · 19397281 (PubMed) · PMC2685875 (PubMed Central)
  9. Checkpoint signaling from a single DNA interstrand crosslink. Ben-Yehoyada M, Wang LC, Kozekov ID, Rizzo CJ, Gottesman ME, Gautier J (2009) Mol Cell 35(5): 704-15
    › Primary publication · 19748363 (PubMed) · PMC2756577 (PubMed Central)
  10. The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence. Huang H, Wang H, Qi N, Lloyd RS, Rizzo CJ, Stone MP (2008) Biochemistry 47(44): 11457-72
    › Primary publication · 18847226 (PubMed) · PMC2646759 (PubMed Central)