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Carmelo Rizzo
Faculty Member
Last active: 1/7/2016

  1. Translesion synthesis across 1,N2-ethenoguanine by human DNA polymerases. Choi JY, Zang H, Angel KC, Kozekov ID, Goodenough AK, Rizzo CJ, Guengerich FP (2006) Chem Res Toxicol 19(6): 879-86
    › Primary publication · 16780368 (PubMed) · PMC3130186 (PubMed Central)
  2. Stereospecific formation of interstrand carbinolamine DNA cross-links by crotonaldehyde- and acetaldehyde-derived alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine adducts in the 5'-CpG-3' sequence. Cho YJ, Wang H, Kozekov ID, Kurtz AJ, Jacob J, Voehler M, Smith J, Harris TM, Lloyd RS, Rizzo CJ, Stone MP (2006) Chem Res Toxicol 19(2): 195-208
    › Primary publication · 16485895 (PubMed) · PMC2631444 (PubMed Central)
  3. Site-specific synthesis of oligonucleotides containing malondialdehyde adducts of deoxyguanosine and deoxyadenosine via a postsynthetic modification strategy. Wang H, Kozekov ID, Kozekova A, Tamura PJ, Marnett LJ, Harris TM, Rizzo CJ (2006) Chem Res Toxicol 19(11): 1467-74
    › Primary publication · 17112234 (PubMed) · PMC2441645 (PubMed Central)
  4. Orientation of the crotonaldehyde-derived N2-[3-Oxo-1(S)-methyl-propyl]-dG DNA adduct hinders interstrand cross-link formation in the 5'-CpG-3' sequence. Cho YJ, Wang H, Kozekov ID, Kozekova A, Kurtz AJ, Jacob J, Voehler M, Smith J, Harris TM, Rizzo CJ, Lloyd RS, Stone MP (2006) Chem Res Toxicol 19(8): 1019-29
    › Primary publication · 16918240 (PubMed)
  5. In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG. Otteneder MB, Knutson CG, Daniels JS, Hashim M, Crews BC, Remmel RP, Wang H, Rizzo C, Marnett LJ (2006) Proc Natl Acad Sci U S A 103(17): 6665-9
    › Primary publication · 16614064 (PubMed) · PMC1458938 (PubMed Central)
  6. Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta selectively produces a two-base deletion in copying the N2-guanyl adduct of 2-amino-3-methylimidazo[4,5-f]quinoline but not the C8 adduct at the NarI G3 site. Choi JY, Stover JS, Angel KC, Chowdhury G, Rizzo CJ, Guengerich FP (2006) J Biol Chem 281(35): 25297-306
    › Primary publication · 16835218 (PubMed)
  7. Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions. Wang F, DeMuro NE, Elmquist CE, Stover JS, Rizzo CJ, Stone MP (2006) J Am Chem Soc 128(31): 10085-95
    › Primary publication · 16881637 (PubMed) · PMC2692337 (PubMed Central)
  8. Structure of an oligodeoxynucleotide containing a butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adduct in the human N-ras codon 61 sequence. Scholdberg TA, Merritt WK, Dean SM, Kowalcyzk A, Harris CM, Harris TM, Rizzo CJ, Lloyd RS, Stone MP (2005) Biochemistry 44(9): 3327-37
    › Primary publication · 15736943 (PubMed)
  9. Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5'-CpG-3' sequence by the acrolein-derived gamma-OH-1,N2-propano-2'-deoxyguanosine DNA adduct. Cho YJ, Kim HY, Huang H, Slutsky A, Minko IG, Wang H, Nechev LV, Kozekov ID, Kozekova A, Tamura P, Jacob J, Voehler M, Harris TM, Lloyd RS, Rizzo CJ, Stone MP (2005) J Am Chem Soc 127(50): 17686-96
    › Primary publication · 16351098 (PubMed) · PMC2631571 (PubMed Central)
  10. Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine. Goodenough AK, Kozekov ID, Zang H, Choi JY, Guengerich FP, Harris TM, Rizzo CJ (2005) Chem Res Toxicol 18(11): 1701-14
    › Primary publication · 16300379 (PubMed) · PMC3135970 (PubMed Central)