Alex Waterson
Faculty Member
Last active: 3/21/2014

  1. Development of potent B-RafV600E inhibitors containing an arylsulfonamide headgroup. Stellwagen JC, Adjabeng GM, Arnone MR, Dickerson SH, Han C, Hornberger KR, King AJ, Mook RA, Petrov KG, Rheault TR, Rominger CM, Rossanese OW, Smitheman KN, Waterson AG, Uehling DE (2011) Bioorg Med Chem Lett 21(15): 4436-40
    › Primary publication · 21733693 (PubMed)
  2. Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α. Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, Salic A, Lee LA, Miller DM, Lee E (2010) Nat Chem Biol 6(11): 829-36
    › Primary publication · 20890287 (PubMed) · PMC3681608 (PubMed Central)
  3. Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines as EGFR and ErbB-2 inhibitors. Stevens KL, Alligood KJ, Alberti JG, Caferro TR, Chamberlain SD, Dickerson SH, Dickson HD, Emerson HK, Griffin RJ, Hubbard RD, Keith BR, Mullin RJ, Petrov KG, Gerding RM, Reno MJ, Rheault TR, Rusnak DW, Sammond DM, Smith SC, Uehling DE, Waterson AG, Wood ER (2009) Bioorg Med Chem Lett 19(1): 21-6
    › Primary publication · 19028424 (PubMed)
  4. Synthesis and evaluation of aniline headgroups for alkynyl thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors. Waterson AG, Petrov KG, Hornberger KR, Hubbard RD, Sammond DM, Smith SC, Dickson HD, Caferro TR, Hinkle KW, Stevens KL, Dickerson SH, Rusnak DW, Spehar GM, Wood ER, Griffin RJ, Uehling DE (2009) Bioorg Med Chem Lett 19(5): 1332-6
    › Primary publication · 19208477 (PubMed)
  5. Room-temperature Pd-catalyzed amidation of aryl bromides using tert-butyl carbamate. Bhagwanth S, Waterson AG, Adjabeng GM, Hornberger KR (2009) J Org Chem 74(12): 4634-7
    › Primary publication · 19518153 (PubMed)
  6. Dual EGFR/ErbB-2 inhibitors from novel pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines. Hubbard RD, Dickerson SH, Emerson HK, Griffin RJ, Reno MJ, Hornberger KR, Rusnak DW, Wood ER, Uehling DE, Waterson AG (2008) Bioorg Med Chem Lett 18(21): 5738-40
    › Primary publication · 18842405 (PubMed)
  7. 6-Ethynylthieno[3,2-d]- and 6-ethynylthieno[2,3-d]pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases. Wood ER, Shewchuk LM, Ellis B, Brignola P, Brashear RL, Caferro TR, Dickerson SH, Dickson HD, Donaldson KH, Gaul M, Griffin RJ, Hassell AM, Keith B, Mullin R, Petrov KG, Reno MJ, Rusnak DW, Tadepalli SM, Ulrich JC, Wagner CD, Vanderwall DE, Waterson AG, Williams JD, White WL, Uehling DE (2008) Proc Natl Acad Sci U S A 105(8): 2773-8
    › Primary publication · 18287036 (PubMed) · PMC2268535 (PubMed Central)
  8. Alkynyl pyrimidines as dual EGFR/ErbB2 kinase inhibitors. Waterson AG, Stevens KL, Reno MJ, Zhang YM, Boros EE, Bouvier F, Rastagar A, Uehling DE, Dickerson SH, Reep B, McDonald OB, Wood ER, Rusnak DW, Alligood KJ, Rudolph SK (2006) Bioorg Med Chem Lett 16(9): 2419-22
    › Primary publication · 16483772 (PubMed)
  9. Studies dealing with thionium ion promoted mannich cyclization reactions. Padwa A, Waterson AG (2000) J Org Chem 65(1): 235-44
    › Primary publication · 10813921 (PubMed)
  10. Bicyclic lactams as chiral homoenolate equivalents: synthesis of (-)-penienone. Waterson AG, Meyers AI (2000) J Org Chem 65(21): 7240-3
    › Primary publication · 11031061 (PubMed)