Douglas Sawyer
Faculty Member
Last active: 7/21/2014

  1. Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes. Lim CC, Zuppinger C, Guo X, Kuster GM, Helmes M, Eppenberger HM, Suter TM, Liao R, Sawyer DB (2004) J Biol Chem 279(9): 8290-9
    › Primary publication · 14676206 (PubMed)
  2. Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy. Arad M, Moskowitz IP, Patel VV, Ahmad F, Perez-Atayde AR, Sawyer DB, Walter M, Li GH, Burgon PG, Maguire CT, Stapleton D, Schmitt JP, Guo XX, Pizard A, Kupershmidt S, Roden DM, Berul CI, Seidman CE, Seidman JG (2003) Circulation 107(22): 2850-6
    › Primary publication · 12782567 (PubMed)
  3. Titin determines the Frank-Starling relation in early diastole. Helmes M, Lim CC, Liao R, Bharti A, Cui L, Sawyer DB (2003) J Gen Physiol 121(2): 97-110
    › Primary publication · 12566538 (PubMed) · PMC2217323 (PubMed Central)
  4. Serum insulin-like growth factor I and risk for heart failure in elderly individuals without a previous myocardial infarction: the Framingham Heart Study. Vasan RS, Sullivan LM, D'Agostino RB, Roubenoff R, Harris T, Sawyer DB, Levy D, Wilson PW (2003) Ann Intern Med 139(8): 642-8
    › Primary publication · 14568852 (PubMed)
  5. Regulation of neuregulin/ErbB signaling by contractile activity in skeletal muscle. Lebrasseur NK, Coté GM, Miller TA, Fielding RA, Sawyer DB (2003) Am J Physiol Cell Physiol 284(5): C1149-55
    › Primary publication · 12519750 (PubMed)
  6. Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt. Fukazawa R, Miller TA, Kuramochi Y, Frantz S, Kim YD, Marchionni MA, Kelly RA, Sawyer DB (2003) J Mol Cell Cardiol 35(12): 1473-9
    › Primary publication · 14654373 (PubMed)
  7. Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study. Vasan RS, Sullivan LM, Roubenoff R, Dinarello CA, Harris T, Benjamin EJ, Sawyer DB, Levy D, Wilson PW, D'Agostino RB, Framingham Heart Study (2003) Circulation 107(11): 1486-91
    › Primary publication · 12654604 (PubMed)
  8. H(2)O(2) regulates cardiac myocyte phenotype via concentration-dependent activation of distinct kinase pathways. Kwon SH, Pimentel DR, Remondino A, Sawyer DB, Colucci WS (2003) J Mol Cell Cardiol 35(6): 615-21
    › Primary publication · 12788379 (PubMed)
  9. Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes. Jain M, Brenner DA, Cui L, Lim CC, Wang B, Pimentel DR, Koh S, Sawyer DB, Leopold JA, Handy DE, Loscalzo J, Apstein CS, Liao R (2003) Circ Res 93(2): e9-16
    › Primary publication · 12829617 (PubMed)
  10. Beta-adrenergic receptor-stimulated apoptosis in cardiac myocytes is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of the mitochondrial pathway. Remondino A, Kwon SH, Communal C, Pimentel DR, Sawyer DB, Singh K, Colucci WS (2003) Circ Res 92(2): 136-8
    › Primary publication · 12574140 (PubMed)