H. Manning
Faculty Member
Last active: 3/22/2018

  1. The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer. Joseph JD, Darimont B, Zhou W, Arrazate A, Young A, Ingalla E, Walter K, Blake RA, Nonomiya J, Guan Z, Kategaya L, Govek SP, Lai AG, Kahraman M, Brigham D, Sensintaffar J, Lu N, Shao G, Qian J, Grillot K, Moon M, Prudente R, Bischoff E, Lee KJ, Bonnefous C, Douglas KL, Julien JD, Nagasawa JY, Aparicio A, Kaufman J, Haley B, Giltnane JM, Wertz IE, Lackner MR, Nannini MA, Sampath D, Schwarz L, Manning HC, Tantawy MN, Arteaga CL, Heyman RA, Rix PJ, Friedman L, Smith ND, Metcalfe C, Hager JH (2016) Elife
    › Primary publication · 27410477 (PubMed) · PMC4961458 (PubMed Central)
  2. Preclinical Evaluation of 4-[18F]Fluoroglutamine PET to Assess ASCT2 Expression in Lung Cancer. Hassanein M, Hight MR, Buck JR, Tantawy MN, Nickels ML, Hoeksema MD, Harris BK, Boyd K, Massion PP, Manning HC (2016) Mol Imaging Biol 18(1): 18-23
    › Primary publication · 25971659 (PubMed) · PMC4644503 (PubMed Central)
  3. New structure-activity relationships of N-acetamide substituted pyrazolopyrimidines as pharmacological ligands of TSPO. Li J, Schulte ML, Nickels ML, Manning HC (2016) Bioorg Med Chem Lett 26(15): 3472-7
    › Primary publication · 27353534 (PubMed) · PMC4993599 (PubMed Central)
  4. Mouse Models of Breast Cancer: Platforms for Discovering Precision Imaging Diagnostics and Future Cancer Medicine. Manning HC, Buck JR, Cook RS (2016) J Nucl Med : 60S-8S
    › Primary publication · 26834104 (PubMed) · PMC6231414 (PubMed Central)
  5. Identification and characterization of EGF receptor in individual exosomes by fluorescence-activated vesicle sorting. Higginbotham JN, Zhang Q, Jeppesen DK, Scott AM, Manning HC, Ochieng J, Franklin JL, Coffey RJ (2016) J Extracell Vesicles : 29254
    › Primary publication · 27345057 (PubMed) · PMC4921784 (PubMed Central)
  6. F-FLT Positron Emission Tomography (PET) is a Pharmacodynamic Marker for EWS-FLI1 Activity and Ewing Sarcoma. Osgood CL, Tantawy MN, Maloney N, Madaj ZB, Peck A, Boguslawski E, Jess J, Buck J, Winn ME, Manning HC, Grohar PJ (2016) Sci Rep : 33926
    › Primary publication · 27671553 (PubMed) · PMC5037393 (PubMed Central)
  7. Activation of GRP/GRP-R signaling contributes to castration-resistant prostate cancer progression. Qiao J, Grabowska MM, Forestier-Roman IS, Mirosevich J, Case TC, Chung DH, Cates JM, Matusik RJ, Manning HC, Jin R (2016) Oncotarget 7(38): 61955-61969
    › Primary publication · 27542219 (PubMed) · PMC5308703 (PubMed Central)
  8. 2-Amino-4-bis(aryloxybenzyl)aminobutanoic acids: A novel scaffold for inhibition of ASCT2-mediated glutamine transport. Schulte ML, Khodadadi AB, Cuthbertson ML, Smith JA, Manning HC (2016) Bioorg Med Chem Lett 26(3): 1044-1047
    › Primary publication · 26750251 (PubMed) · PMC4727990 (PubMed Central)
  9. World Molecular Imaging Congress 2015: precision medicine visualized. Manning HC (2015) Mol Imaging Biol 17(3): 295-6
    › Primary publication · 25862478 (PubMed)
  10. Utility of [18 F]FLT-PET to assess treatment response in trastuzumab-resistant and trastuzumab-sensitive HER2-overexpressing human breast cancer xenografts. Whisenant JG, McIntyre JO, Peterson TE, Kang H, Sánchez V, Manning HC, Arteaga CL, Yankeelov TE (2015) Mol Imaging Biol 17(1): 119-28
    › Primary publication · 25034624 (PubMed) · PMC4311727 (PubMed Central)