Ethan Lee
Faculty Member
Last active: 7/23/2019

  1. lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling. Lu Y, Zhao X, Liu Q, Li C, Graves-Deal R, Cao Z, Singh B, Franklin JL, Wang J, Hu H, Wei T, Yang M, Yeatman TJ, Lee E, Saito-Diaz K, Hinger S, Patton JG, Chung CH, Emmrich S, Klusmann JH, Fan D, Coffey RJ (2017) Nat Med 23(11): 1331-1341
    › Primary publication · 29035371 (PubMed) · PMC5961502 (PubMed Central)
  2. Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma. Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss WA, Rodriguez C, Mehrdad N, Nguyen DM, Ayad NG, Rai P, Capobianco AJ, Robbins DJ (2017) Oncogene 36(45): 6306-6314
    › Primary publication · 28714964 (PubMed) · PMC5680121 (PubMed Central)
  3. Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors. Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, Jin K, Nguyen DM, Sands LR, Marchetti F, Abreu MT, Cobb MH, Capobianco AJ, Lee E, Robbins DJ (2017) Sci Signal 10(485)
    › Primary publication · 28655862 (PubMed) · PMC5555225 (PubMed Central)
  4. Casein kinase1α activators, a precision weapon for CRC. Li B, Lee E, Robbins DJ (2017) Oncotarget 8(57): 96462-96463
    › Primary publication · 29228537 (PubMed) · PMC5722489 (PubMed Central)
  5. Blocking TGF- and -Catenin Epithelial Crosstalk Exacerbates CKD. Nlandu-Khodo S, Neelisetty S, Phillips M, Manolopoulou M, Bhave G, May L, Clark PE, Yang H, Fogo AB, Harris RC, Taketo MM, Lee E, Gewin LS (2017) J Am Soc Nephrol 28(12): 3490-3503
    › Primary publication · 28701516 (PubMed) · PMC5698068 (PubMed Central)
  6. Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase. Wang Z, Tacchelly-Benites O, Yang E, Thorne CA, Nojima H, Lee E, Ahmed Y (2016) Genetics 203(1): 269-81
    › Primary publication · 26975665 (PubMed) · PMC4858779 (PubMed Central)
  7. Wnt pathway activation by ADP-ribosylation. Yang E, Tacchelly-Benites O, Wang Z, Randall MP, Tian A, Benchabane H, Freemantle S, Pikielny C, Tolwinski NS, Lee E, Ahmed Y (2016) Nat Commun : 11430
    › Primary publication · 27138857 (PubMed) · PMC4857404 (PubMed Central)
  8. The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis. Astudillo L, Da Silva TG, Wang Z, Han X, Jin K, VanWye J, Zhu X, Weaver K, Oashi T, Lopes PE, Orton D, Neitzel LR, Lee E, Landgraf R, Robbins DJ, MacKerell AD, Capobianco AJ (2016) Cancer Res 76(12): 3593-603
    › Primary publication · 27197169 (PubMed) · PMC4911243 (PubMed Central)
  9. Reconstitution of the Cytoplasmic Regulation of the Wnt Signaling Pathway Using Xenopus Egg Extracts. Hyde AS, Hang BI, Lee E (2016) Methods Mol Biol : 101-9
    › Primary publication · 27590156 (PubMed) · PMC5567996 (PubMed Central)
  10. Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E (2016) Cell Rep 15(9): 1920-9
    › Primary publication · 27210761 (PubMed) · PMC4889555 (PubMed Central)