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Ethan Lee
Faculty Member
Last active: 2/6/2020

  1. XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling. Hanson AJ, Wallace HA, Freeman TJ, Beauchamp RD, Lee LA, Lee E (2012) Mol Cell 45(5): 619-28
    › Primary publication · 22304967 (PubMed) · PMC3299836 (PubMed Central)
  2. Screening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs. Hang BI, Thorne CA, Robbins DJ, Huppert SS, Lee LA, Lee E (2012) Bioorg Med Chem 20(6): 1869-77
    › Primary publication · 22261025 (PubMed) · PMC3298638 (PubMed Central)
  3. Regulation of dynein localization and centrosome positioning by Lis-1 and asunder during Drosophila spermatogenesis. Sitaram P, Anderson MA, Jodoin JN, Lee E, Lee LA (2012) Development 139(16): 2945-54
    › Primary publication · 22764052 (PubMed) · PMC3403104 (PubMed Central)
  4. Human Asunder promotes dynein recruitment and centrosomal tethering to the nucleus at mitotic entry. Jodoin JN, Shboul M, Sitaram P, Zein-Sabatto H, Reversade B, Lee E, Lee LA (2012) Mol Biol Cell 23(24): 4713-24
    › Primary publication · 23097494 (PubMed) · PMC3521680 (PubMed Central)
  5. A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts. Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, Lee LA, Robbins DJ, Huppert SS, Lee E (2011) J Biomol Screen 16(9): 995-1006
    › Primary publication · 21859680 (PubMed) · PMC3694444 (PubMed Central)
  6. Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α. Thorne CA, Hanson AJ, Schneider J, Tahinci E, Orton D, Cselenyi CS, Jernigan KK, Meyers KC, Hang BI, Waterson AG, Kim K, Melancon B, Ghidu VP, Sulikowski GA, LaFleur B, Salic A, Lee LA, Miller DM, Lee E (2010) Nat Chem Biol 6(11): 829-36
    › Primary publication · 20890287 (PubMed) · PMC3681608 (PubMed Central)
  7. sFRP2 suppression of bone morphogenic protein (BMP) and Wnt signaling mediates mesenchymal stem cell (MSC) self-renewal promoting engraftment and myocardial repair. Alfaro MP, Vincent A, Saraswati S, Thorne CA, Hong CC, Lee E, Young PP (2010) J Biol Chem 285(46): 35645-53
    › Primary publication · 20826809 (PubMed) · PMC2975189 (PubMed Central)
  8. Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling. Saraswati S, Alfaro MP, Thorne CA, Atkinson J, Lee E, Young PP (2010) PLoS One 5(11): e15521
    › Primary publication · 21170416 (PubMed) · PMC2993965 (PubMed Central)
  9. Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization. Speirs CK, Jernigan KK, Kim SH, Cha YI, Lin F, Sepich DS, DuBois RN, Lee E, Solnica-Krezel L (2010) Development 137(8): 1327-37
    › Primary publication · 20332150 (PubMed) · PMC2847468 (PubMed Central)
  10. Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity. Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E (2010) Sci Signal 3(121): ra37
    › Primary publication · 20460648 (PubMed) · PMC3088111 (PubMed Central)