Ethan Lee
Faculty Member
Last active: 4/10/2019

  1. Discovering small molecules as Wnt inhibitors that promote heart regeneration and injury repair. Xie S, Fu W, Yu G, Hu X, Lai KS, Peng X, Zhou Y, Zhu X, Christov P, Sawyer L, Ni TT, Sulikowski GA, Yang Z, Lee E, Zeng C, Wang WE, Zhong TP (2019) J Mol Cell Biol
    › Primary publication · 30925593 (PubMed)
  2. Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway. Neitzel LR, Spencer ZT, Nayak A, Cselenyi CS, Benchabane H, Youngblood CQ, Zouaoui A, Ng V, Stephens L, Hann T, Patton JG, Robbins D, Ahmed Y, Lee E (2019) Mech Dev : 20-31
    › Primary publication · 30904594 (PubMed)
  3. Blood vessel epicardial substance (BVES) reduces LRP6 receptor and cytoplasmic -catenin levels to modulate Wnt signaling and intestinal homeostasis. Thompson JJ, Short SP, Parang B, Brown RE, Li C, Ng VH, Saito-Diaz K, Choksi YA, Washington MK, Smith JJ, Fingleton B, Brand T, Lee E, Coffey RJ, Williams CS (2019) Carcinogenesis
    › Primary publication · 30689807 (PubMed)
  4. Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling. Ng VH, Hang BI, Sawyer LM, Neitzel LR, Crispi EE, Rose KL, Popay TM, Zhong A, Lee LA, Tansey WP, Huppert S, Lee E (2018) J Cell Sci 131(10)
    › Primary publication · 29678905 (PubMed) · PMC6031333 (PubMed Central)
  5. Chemical Screening Using Cell-Free Egg Extract. Broadus MR, Lee E (2018) Cold Spring Harb Protoc 2018(8): pdb.prot098277
    › Primary publication · 29475996 (PubMed) · PMC6368528 (PubMed Central)
  6. Characterization of a null allele in . Neitzel LR, Broadus MR, Zhang N, Sawyer L, Wallace HA, Merkle JA, Jodoin JN, Sitaram P, Crispi EE, Rork W, Lee LA, Pan D, Gould KL, Page-McCaw A, Lee E (2018) Biol Open 7(7)
    › Primary publication · 29945873 (PubMed) · PMC6078348 (PubMed Central)
  7. APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway. Saito-Diaz K, Benchabane H, Tiwari A, Tian A, Li B, Thompson JJ, Hyde AS, Sawyer LM, Jodoin JN, Santos E, Lee LA, Coffey RJ, Beauchamp RD, Williams CS, Kenworthy AK, Robbins DJ, Ahmed Y, Lee E (2018) Dev Cell 44(5): 566-581.e8
    › Primary publication · 29533772 (PubMed) · PMC5884143 (PubMed Central)
  8. The MAPK Pathway Regulates Intrinsic Resistance to BET Inhibitors in Colorectal Cancer. Ma Y, Wang L, Neitzel LR, Loganathan SN, Tang N, Qin L, Crispi EE, Guo Y, Knapp S, Beauchamp RD, Lee E, Wang J (2017) Clin Cancer Res 23(8): 2027-2037
    › Primary publication · 27678457 (PubMed) · PMC5368030 (PubMed Central)
  9. Pharmacologic Inhibition of β-Catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor. Polosukhina D, Love HD, Moses HL, Lee E, Zent R, Clark PE (2017) Oncol Res 25(9): 1653-1664
    › Primary publication · 28695795 (PubMed) · PMC5670010 (PubMed Central)
  10. lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling. Lu Y, Zhao X, Liu Q, Li C, Graves-Deal R, Cao Z, Singh B, Franklin JL, Wang J, Hu H, Wei T, Yang M, Yeatman TJ, Lee E, Saito-Diaz K, Hinger S, Patton JG, Chung CH, Emmrich S, Klusmann JH, Fan D, Coffey RJ (2017) Nat Med 23(11): 1331-1341
    › Primary publication · 29035371 (PubMed) · PMC5961502 (PubMed Central)