F. Guengerich
Faculty Member
Last active: 3/3/2020

  1. In Vitro Activation of Cytochrome P450 46A1 (CYP46A1) by Efavirenz-Related Compounds. Mast N, Verwilst P, Wilkey CJ, Guengerich FP, Pikuleva IA (2020) J Med Chem 63(12): 6477-6488
    › Primary publication · 31617715 (PubMed) · PMC7226586 (PubMed Central)
  2. FEMA GRAS assessment of natural flavor complexes: Mint, buchu, dill and caraway derived flavoring ingredients. Cohen SM, Eisenbrand G, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IMCM, Bastaki M, Davidsen JM, Harman CL, McGowen MM, Taylor SV (2020) Food Chem Toxicol : 110870
    › Primary publication · 31604112 (PubMed)
  3. FEMA GRAS assessment of natural flavor complexes: Cinnamomum and Myroxylon-derived flavoring ingredients. Rietjens IMCM, Cohen SM, Eisenbrand G, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rosol TJ, Davidsen JM, Harman CL, Murray IJ, Taylor SV (2020) Food Chem Toxicol : 110949
    › Primary publication · 31751643 (PubMed)
  4. Engineering cytochrome P450 enzyme systems for biomedical and biotechnological applications. Li Z, Jiang Y, Guengerich FP, Ma L, Li S, Zhang W (2020) J Biol Chem 295(3): 833-849
    › Primary publication · 31811088 (PubMed) · PMC6970918 (PubMed Central)
  5. Validation of Human Sterol 14α-Demethylase (CYP51) Druggability: Structure-Guided Design, Synthesis, and Evaluation of Stoichiometric, Functionally Irreversible Inhibitors. Friggeri L, Hargrove TY, Wawrzak Z, Guengerich FP, Lepesheva GI (2019) J Med Chem 62(22): 10391-10401
    › Primary publication · 31663733 (PubMed) · PMC6881533 (PubMed Central)
  6. The abundant DNA adduct -methyl deoxyguanosine contributes to miscoding during replication by human DNA polymerase η. Njuma OJ, Su Y, Guengerich FP (2019) J Biol Chem 294(26): 10253-10265
    › Primary publication · 31101656 (PubMed) · PMC6664181 (PubMed Central)
  7. Synthesis and Characterization of Site-Specific O -Alkylguanine DNA-Alkyl Transferase-Oligonucleotide Crosslinks. Ghodke PP, Albertolle ME, Johnson KM, Guengerich FP (2019) Curr Protoc Nucleic Acid Chem 76(1): e74
    › Primary publication · 30657645 (PubMed) · PMC6504252 (PubMed Central)
  8. Oxidation of Flavone, 5-Hydroxyflavone, and 5,7-Dihydroxyflavone to Mono-, Di-, and Tri-Hydroxyflavones by Human Cytochrome P450 Enzymes. Nagayoshi H, Murayama N, Kakimoto K, Tsujino M, Takenaka S, Katahira J, Lim YR, Kim D, Yamazaki H, Komori M, Guengerich FP, Shimada T (2019) Chem Res Toxicol 32(6): 1268-1280
    › Primary publication · 30964977 (PubMed)
  9. Mitochondrially targeted cytochrome P450 2D6 is involved in monomethylamine-induced neuronal damage in mouse models. Chattopadhyay M, Chowdhury AR, Feng T, Assenmacher CA, Radaelli E, Guengerich FP, Avadhani NG (2019) J Biol Chem 294(26): 10336-10348
    › Primary publication · 31113867 (PubMed) · PMC6664168 (PubMed Central)
  10. Kinetic Modeling of Steady-State Situations in Cytochrome P450 Enzyme Reactions. Guengerich FP (2019) Drug Metab Dispos 47(11): 1232-1239
    › Primary publication · 31427434 (PubMed) · PMC6815944 (PubMed Central)