Christine Eischen
Faculty Member
Last active: 1/20/2015

  1. Mdm2 promotes genetic instability and transformation independent of p53. Bouska A, Lushnikova T, Plaza S, Eischen CM (2008) Mol Cell Biol 28(15): 4862-74
    › Primary publication · 18541670 (PubMed) · PMC2493369 (PubMed Central)
  2. Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells. Mudhasani R, Zhu Z, Hutvagner G, Eischen CM, Lyle S, Hall LL, Lawrence JB, Imbalzano AN, Jones SN (2008) J Cell Biol 181(7): 1055-63
    › Primary publication · 18591425 (PubMed) · PMC2442212 (PubMed Central)
  3. Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells. Wang P, Lushnikova T, Odvody J, Greiner TC, Jones SN, Eischen CM (2008) Oncogene 27(11): 1590-8
    › Primary publication · 17828300 (PubMed)
  4. A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability. Tompkins VS, Hagen J, Frazier AA, Lushnikova T, Fitzgerald MP, di Tommaso A, Ladeveze V, Domann FE, Eischen CM, Quelle DE (2007) J Biol Chem 282(2): 1322-33
    › Primary publication · 17110379 (PubMed)
  5. Decreased Mdm2 expression inhibits tumor development induced by loss of ARF. Wang P, Greiner TC, Lushnikova T, Eischen CM (2006) Oncogene 25(26): 3708-18
    › Primary publication · 16491126 (PubMed)
  6. Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair. Alt JR, Bouska A, Fernandez MR, Cerny RL, Xiao H, Eischen CM (2005) J Biol Chem 280(19): 18771-81
    › Primary publication · 15734743 (PubMed)
  7. Loss of one allele of ARF rescues Mdm2 haploinsufficiency effects on apoptosis and lymphoma development. Eischen CM, Alt JR, Wang P (2004) Oncogene 23(55): 8931-40
    › Primary publication · 15467748 (PubMed)
  8. Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis. Alt JR, Greiner TC, Cleveland JL, Eischen CM (2003) EMBO J 22(6): 1442-50
    › Primary publication · 12628936 (PubMed) · PMC151074 (PubMed Central)
  9. The RING domain of Mdm2 can inhibit cell proliferation. Dang J, Kuo ML, Eischen CM, Stepanova L, Sherr CJ, Roussel MF (2002) Cancer Res 62(4): 1222-30
    › Primary publication · 11861407 (PubMed)
  10. Loss of Bax alters tumor spectrum and tumor numbers in ARF-deficient mice. Eischen CM, Rehg JE, Korsmeyer SJ, Cleveland JL (2002) Cancer Res 62(7): 2184-91
    › Primary publication · 11929842 (PubMed)