Utpal Dave
Faculty Member
Last active: 2/22/2016

  1. Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm. Chmielecki J, Peifer M, Viale A, Hutchinson K, Giltnane J, Socci ND, Hollis CJ, Dean RS, Yenamandra A, Jagasia M, Kim AS, Davé UP, Thomas RK, Pao W (2012) Genes Chromosomes Cancer 51(1): 54-65
    › Primary publication · 21938754 (PubMed)
  2. Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia. Aue G, Du Y, Cleveland SM, Smith SB, Davé UP, Liu D, Weniger MA, Metais JY, Jenkins NA, Copeland NG, Dunbar CE (2011) Blood 118(17): 4674-81
    › Primary publication · 21878674 (PubMed) · PMC3208283 (PubMed Central)
  3. FERM domain mutations induce gain of function in JAK3 in adult T-cell leukemia/lymphoma. Elliott NE, Cleveland SM, Grann V, Janik J, Waldmann TA, Davé UP (2011) Blood 118(14): 3911-21
    › Primary publication · 21821710 (PubMed) · PMC3193267 (PubMed Central)
  4. A role for proapoptotic Bax and Bak in T-cell differentiation and transformation. Biswas S, Shi Q, Matise L, Cleveland S, Dave U, Zinkel S (2010) Blood 116(24): 5237-46
    › Primary publication · 20813900 (PubMed) · PMC3012541 (PubMed Central)
  5. Murine leukemias with retroviral insertions at Lmo2 are predictive of the leukemias induced in SCID-X1 patients following retroviral gene therapy. Davé UP, Akagi K, Tripathi R, Cleveland SM, Thompson MA, Yi M, Stephens R, Downing JR, Jenkins NA, Copeland NG (2009) PLoS Genet 5(5): e1000491
    › Primary publication · 19461887 (PubMed) · PMC2679194 (PubMed Central)
  6. Leukemia takes center (late) stage. Davé UP (2008) Blood 112(6): 2175-6
    › Primary publication · 18779397 (PubMed)
  7. Gene therapy insertional mutagenesis insights. Davé UP, Jenkins NA, Copeland NG (2004) Science 303(5656): 333
    › Primary publication · 14726584 (PubMed)
  8. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Ye J, Rawson RB, Komuro R, Chen X, Davé UP, Prywes R, Brown MS, Goldstein JL (2000) Mol Cell 6(6): 1355-64
    › Primary publication · 11163209 (PubMed)
  9. Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by site-2 protease. Ye J, Davé UP, Grishin NV, Goldstein JL, Brown MS (2000) Proc Natl Acad Sci U S A 97(10): 5123-8
    › Primary publication · 10805775 (PubMed) · PMC25792 (PubMed Central)
  10. Second-site cleavage in sterol regulatory element-binding protein occurs at transmembrane junction as determined by cysteine panning. Duncan EA, Davé UP, Sakai J, Goldstein JL, Brown MS (1998) J Biol Chem 273(28): 17801-9
    › Primary publication · 9651382 (PubMed)