David Cortez
Faculty Member
Last active: 2/4/2016

  1. Cyclin-dependent kinase 2 dependent phosphorylation of ATRIP regulates the G2-M checkpoint response to DNA damage. Myers JS, Zhao R, Xu X, Ham AJ, Cortez D (2007) Cancer Res 67(14): 6685-90
    › Primary publication · 17638878 (PubMed) · PMC2728292 (PubMed Central)
  2. Rapid activation of ATR by ionizing radiation requires ATM and Mre11. Myers JS, Cortez D (2006) J Biol Chem 281(14): 9346-50
    › Primary publication · 16431910 (PubMed) · PMC1821075 (PubMed Central)
  3. DDB1 maintains genome integrity through regulation of Cdt1. Lovejoy CA, Lock K, Yenamandra A, Cortez D (2006) Mol Cell Biol 26(21): 7977-90
    › Primary publication · 16940174 (PubMed) · PMC1636754 (PubMed Central)
  4. Unwind and slow down: checkpoint activation by helicase and polymerase uncoupling. Cortez D (2005) Genes Dev 19(9): 1007-12
    › Primary publication · 15879550 (PubMed) · PMC1360198 (PubMed Central)
  5. ATRIP oligomerization is required for ATR-dependent checkpoint signaling. Ball HL, Cortez D (2005) J Biol Chem 280(36): 31390-6
    › Primary publication · 16027118 (PubMed) · PMC1360181 (PubMed Central)
  6. ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation. Ball HL, Myers JS, Cortez D (2005) Mol Biol Cell 16(5): 2372-81
    › Primary publication · 15743907 (PubMed) · PMC1087242 (PubMed Central)
  7. Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases. Cortez D, Glick G, Elledge SJ (2004) Proc Natl Acad Sci U S A 101(27): 10078-83
    › Primary publication · 15210935 (PubMed) · PMC454167 (PubMed Central)
  8. Caffeine inhibits checkpoint responses without inhibiting the ataxia-telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) protein kinases. Cortez D (2003) J Biol Chem 278(39): 37139-45
    › Primary publication · 12847089 (PubMed)
  9. Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin. Zou L, Cortez D, Elledge SJ (2002) Genes Dev 16(2): 198-208
    › Primary publication · 11799063 (PubMed) · PMC155323 (PubMed Central)
  10. Direct DNA binding by Brca1. Paull TT, Cortez D, Bowers B, Elledge SJ, Gellert M (2001) Proc Natl Acad Sci U S A 98(11): 6086-91
    › Primary publication · 11353843 (PubMed) · PMC33426 (PubMed Central)