David Cortez
Faculty Member
Last active: 2/4/2016

  1. A novel splice site mutation in SMARCAL1 results in aberrant exon definition in a child with Schimke immunoosseous dysplasia. Carroll C, Hunley TE, Guo Y, Cortez D (2015) Am J Med Genet A 167A(10): 2260-4
    › Primary publication · 25943327 (PubMed) · PMC4743909 (PubMed Central)
  2. SV40 utilizes ATM kinase activity to prevent non-homologous end joining of broken viral DNA replication products. Sowd GA, Mody D, Eggold J, Cortez D, Friedman KL, Fanning E (2014) PLoS Pathog 10(12): e1004536
    › Primary publication · 25474690 (PubMed) · PMC4256475 (PubMed Central)
  3. Phosphorylation of a C-terminal auto-inhibitory domain increases SMARCAL1 activity. Carroll C, Bansbach CE, Zhao R, Jung SY, Qin J, Cortez D (2014) Nucleic Acids Res 42(2): 918-25
    › Primary publication · 24150942 (PubMed) · PMC3902923 (PubMed Central)
  4. Mutation of serine 1333 in the ATR HEAT repeats creates a hyperactive kinase. Luzwick JW, Nam EA, Zhao R, Cortez D (2014) PLoS One 9(6): e99397
    › Primary publication · 24901225 (PubMed) · PMC4047089 (PubMed Central)
  5. Fork reversal, too much of a good thing. Couch FB, Cortez D (2014) Cell Cycle 13(7): 1049-50
    › Primary publication · 24553113 (PubMed) · PMC4013150 (PubMed Central)
  6. Discovery of a potent stapled helix peptide that binds to the 70N domain of replication protein A. Frank AO, Vangamudi B, Feldkamp MD, Souza-Fagundes EM, Luzwick JW, Cortez D, Olejniczak ET, Waterson AG, Rossanese OW, Chazin WJ, Fesik SW (2014) J Med Chem 57(6): 2455-61
    › Primary publication · 24491171 (PubMed) · PMC3969094 (PubMed Central)
  7. ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency. Mohni KN, Kavanaugh GM, Cortez D (2014) Cancer Res 74(10): 2835-45
    › Primary publication · 24662920 (PubMed) · PMC4043842 (PubMed Central)
  8. A structure-specific nucleic acid-binding domain conserved among DNA repair proteins. Mason AC, Rambo RP, Greer B, Pritchett M, Tainer JA, Cortez D, Eichman BF (2014) Proc Natl Acad Sci U S A 111(21): 7618-23
    › Primary publication · 24821763 (PubMed) · PMC4040553 (PubMed Central)
  9. Substrate-selective repair and restart of replication forks by DNA translocases. B├ętous R, Couch FB, Mason AC, Eichman BF, Manosas M, Cortez D (2013) Cell Rep 3(6): 1958-69
    › Primary publication · 23746452 (PubMed) · PMC3700663 (PubMed Central)
  10. Schimke Immunoosseous Dysplasia associated with undifferentiated carcinoma and a novel SMARCAL1 mutation in a child. Carroll C, Badu-Nkansah A, Hunley T, Baradaran-Heravi A, Cortez D, Frangoul H (2013) Pediatr Blood Cancer 60(9): E88-90
    › Primary publication · 23630135 (PubMed) · PMC3713188 (PubMed Central)