Rebecca Cook
Faculty Member
Last active: 4/15/2019

  1. Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactation. Sandahl M, Hunter DM, Strunk KE, Earp HS, Cook RS (2010) BMC Dev Biol : 122
    › Primary publication · 21192804 (PubMed) · PMC3022573 (PubMed Central)
  2. Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy. Zhuang G, Brantley-Sieders DM, Vaught D, Yu J, Xie L, Wells S, Jackson D, Muraoka-Cook R, Arteaga C, Chen J (2010) Cancer Res 70(1): 299-308
    › Primary publication · 20028874 (PubMed) · PMC3859619 (PubMed Central)
  3. Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation. Mahajan K, Coppola D, Challa S, Fang B, Chen YA, Zhu W, Lopez AS, Koomen J, Engelman RW, Rivera C, Muraoka-Cook RS, Cheng JQ, Schönbrunn E, Sebti SM, Earp HS, Mahajan NP (2010) PLoS One 5(3): e9646
    › Primary publication · 20333297 (PubMed) · PMC2841635 (PubMed Central)
  4. The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation. Feng SM, Muraoka-Cook RS, Hunter D, Sandahl MA, Caskey LS, Miyazawa K, Atfi A, Earp HS (2009) Mol Cell Biol 29(3): 892-906
    › Primary publication · 19047365 (PubMed) · PMC2630679 (PubMed Central)
  5. Inhibition of mammalian target of rapamycin is required for optimal antitumor effect of HER2 inhibitors against HER2-overexpressing cancer cells. Miller TW, Forbes JT, Shah C, Wyatt SK, Manning HC, Olivares MG, Sanchez V, Dugger TC, de Matos Granja N, Narasanna A, Cook RS, Kennedy JP, Lindsley CW, Arteaga CL (2009) Clin Cancer Res 15(23): 7266-76
    › Primary publication · 19934303 (PubMed) · PMC2787848 (PubMed Central)
  6. ErbB4 splice variants Cyt1 and Cyt2 differ by 16 amino acids and exert opposing effects on the mammary epithelium in vivo. Muraoka-Cook RS, Sandahl MA, Strunk KE, Miraglia LC, Husted C, Hunter DM, Elenius K, Chodosh LA, Earp HS (2009) Mol Cell Biol 29(18): 4935-48
    › Primary publication · 19596786 (PubMed) · PMC2738276 (PubMed Central)
  7. The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling. Brantley-Sieders DM, Zhuang G, Hicks D, Fang WB, Hwang Y, Cates JM, Coffman K, Jackson D, Bruckheimer E, Muraoka-Cook RS, Chen J (2008) J Clin Invest 118(1): 64-78
    › Primary publication · 18079969 (PubMed) · PMC2129239 (PubMed Central)
  8. Prolactin and ErbB4/HER4 signaling interact via Janus kinase 2 to induce mammary epithelial cell gene expression differentiation. Muraoka-Cook RS, Sandahl M, Hunter D, Miraglia L, Earp HS (2008) Mol Endocrinol 22(10): 2307-21
    › Primary publication · 18653779 (PubMed) · PMC2582536 (PubMed Central)
  9. ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition. Muraoka-Cook RS, Feng SM, Strunk KE, Earp HS (2008) J Mammary Gland Biol Neoplasia 13(2): 235-46
    › Primary publication · 18437540 (PubMed) · PMC3325098 (PubMed Central)
  10. The HER4 cytoplasmic domain, but not its C terminus, inhibits mammary cell proliferation. Feng SM, Sartor CI, Hunter D, Zhou H, Yang X, Caskey LS, Dy R, Muraoka-Cook RS, Earp HS (2007) Mol Endocrinol 21(8): 1861-76
    › Primary publication · 17505063 (PubMed) · PMC2917064 (PubMed Central)