Alan Brash
Last active: 3/22/2018

  1. A critical role of non-active site residues on cyclooxygenase helices 5 and 6 in the control of prostaglandin stereochemistry at carbon 15. Valmsen K, Boeglin WE, Järving R, Järving I, Varvas K, Brash AR, Samel N (2007) J Biol Chem 282(38): 28157-63
    › Primary publication · 17652088 (PubMed)
  2. On the relationship of coral allene oxide synthase to catalase. A single active site mutation that induces catalase activity in coral allene oxide synthase. Tosha T, Uchida T, Brash AR, Kitagawa T (2006) J Biol Chem 281(18): 12610-7
    › Primary publication · 16513636 (PubMed)
  3. Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity. Furse KE, Pratt DA, Schneider C, Brash AR, Porter NA, Lybrand TP (2006) Biochemistry 45(10): 3206-18
    › Primary publication · 16519515 (PubMed) · PMC2504531 (PubMed Central)
  4. Interleukin-4 induces 15-lipoxygenase-1 expression in human orbital fibroblasts from patients with Graves disease. Evidence for anatomic site-selective actions of Th2 cytokines. Chen B, Tsui S, Boeglin WE, Douglas RS, Brash AR, Smith TJ (2006) J Biol Chem 281(27): 18296-306
    › Primary publication · 16675443 (PubMed)
  5. Identification and characterization of an arachidonate 11R-lipoxygenase. Mortimer M, Järving R, Brash AR, Samel N, Järving I (2006) Arch Biochem Biophys 445(1): 147-55
    › Primary publication · 16321357 (PubMed)
  6. Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin. Yu Z, Schneider C, Boeglin WE, Brash AR (2006) Arch Biochem Biophys 455(2): 188-96
    › Primary publication · 17045234 (PubMed) · PMC2636205 (PubMed Central)
  7. Demonstration of ubiquitin thiolester formation of UBE2Q2 (UBCi), a novel ubiquitin-conjugating enzyme with implantation site-specific expression. Melner MH, Haas AL, Klein JM, Brash AR, Boeglin WE, Nagdas SK, Winfrey VP, Olson GE (2006) Biol Reprod 75(3): 395-406
    › Primary publication · 16760379 (PubMed)
  8. The structure of coral allene oxide synthase reveals a catalase adapted for metabolism of a fatty acid hydroperoxide. Oldham ML, Brash AR, Newcomer ME (2005) Proc Natl Acad Sci U S A 102(2): 297-302
    › Primary publication · 15625113 (PubMed) · PMC544295 (PubMed Central)
  9. Synthesis of dihydroperoxides of linoleic and linolenic acids and studies on their transformation to 4-hydroperoxynonenal. Schneider C, Boeglin WE, Yin H, Ste DF, Hachey DL, Porter NA, Brash AR (2005) Lipids 40(11): 1155-62
    › Primary publication · 16459928 (PubMed)
  10. On the relationships of substrate orientation, hydrogen abstraction, and product stereochemistry in single and double dioxygenations by soybean lipoxygenase-1 and its Ala542Gly mutant. Coffa G, Imber AN, Maguire BC, Laxmikanthan G, Schneider C, Gaffney BJ, Brash AR (2005) J Biol Chem 280(46): 38756-66
    › Primary publication · 16157595 (PubMed) · PMC1351262 (PubMed Central)