Alan Brash
Last active: 3/22/2018

  1. Identification of two cyclooxygenase active site residues, Leucine 384 and Glycine 526, that control carbon ring cyclization in prostaglandin biosynthesis. Schneider C, Boeglin WE, Brash AR (2004) J Biol Chem 279(6): 4404-14
    › Primary publication · 14594816 (PubMed)
  2. Differential expression of genes in the endometrium at implantation: upregulation of a novel member of the E2 class of ubiquitin-conjugating enzymes. Melner MH, Ducharme NA, Brash AR, Winfrey VP, Olson GE (2004) Biol Reprod 70(2): 406-14
    › Primary publication · 14561654 (PubMed)
  3. Autoxidative transformation of chiral omega6 hydroxy linoleic and arachidonic acids to chiral 4-hydroxy-2E-nonenal. Schneider C, Porter NA, Brash AR (2004) Chem Res Toxicol 17(7): 937-41
    › Primary publication · 15257619 (PubMed)
  4. A single active site residue directs oxygenation stereospecificity in lipoxygenases: stereocontrol is linked to the position of oxygenation. Coffa G, Brash AR (2004) Proc Natl Acad Sci U S A 101(44): 15579-84
    › Primary publication · 15496467 (PubMed) · PMC524819 (PubMed Central)
  5. The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase. Yu Z, Schneider C, Boeglin WE, Marnett LJ, Brash AR (2003) Proc Natl Acad Sci U S A 100(16): 9162-7
    › Primary publication · 12881489 (PubMed) · PMC170889 (PubMed Central)
  6. Elevated expression of 12/15-lipoxygenase and cyclooxygenase-2 in a transgenic mouse model of prostate carcinoma. Shappell SB, Olson SJ, Hannah SE, Manning S, Roberts RL, Masumori N, Jisaka M, Boeglin WE, Vader V, Dave DS, Shook MF, Thomas TZ, Funk CD, Brash AR, Matusik RJ (2003) Cancer Res 63(9): 2256-67
    › Primary publication · 12727848 (PubMed)
  7. Lipoxygenase-catalyzed formation of R-configuration hydroperoxides. Schneider C, Brash AR (2002) Prostaglandins Other Lipid Mediat : 291-301
    › Primary publication · 12432924 (PubMed)
  8. Inhibition of peroxisome proliferator-activated receptor (PPAR)-mediated keratinocyte differentiation by lipoxygenase inhibitors. Thuillier P, Brash AR, Kehrer JP, Stimmel JB, Leesnitzer LM, Yang P, Newman RA, Fischer SM (2002) Biochem J 366(Pt 3): 901-10
    › Primary publication · 12069687 (PubMed) · PMC1222830 (PubMed Central)
  9. Detection of the 15-acetate of prostaglandin E2 methyl ester as a prominent component of the prostaglandins in the gorgonian coral Plexaura homomalla. Schneider C, Manier ML, Hachey DL, Brash AR (2002) Lipids 37(2): 217-21
    › Primary publication · 11908914 (PubMed)
  10. Control of prostaglandin stereochemistry at the 15-carbon by cyclooxygenases-1 and -2. A critical role for serine 530 and valine 349. Schneider C, Boeglin WE, Prusakiewicz JJ, Rowlinson SW, Marnett LJ, Samel N, Brash AR (2002) J Biol Chem 277(1): 478-85
    › Primary publication · 11677234 (PubMed)