Alan Brash
Last active: 3/22/2018

  1. The structural basis for specificity in lipoxygenase catalysis. Newcomer ME, Brash AR (2015) Protein Sci 24(3): 298-309
    › Primary publication · 25524168 (PubMed) · PMC4353356 (PubMed Central)
  2. The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier. Muñoz-Garcia A, Thomas CP, Keeney DS, Zheng Y, Brash AR (2014) Biochim Biophys Acta 1841(3): 401-8
    › Primary publication · 24021977 (PubMed) · PMC4116325 (PubMed Central)
  3. Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction. Teder T, Boeglin WE, Brash AR (2014) J Lipid Res 55(12): 2587-96
    › Primary publication · 25293588 (PubMed) · PMC4242451 (PubMed Central)
  4. Inhibitory effects of a novel Val to Thr mutation on the distal heme of human catalase. Mashhadi Z, Boeglin WE, Brash AR (2014) Biochimie : 180-3
    › Primary publication · 25086217 (PubMed) · PMC4250446 (PubMed Central)
  5. Crystal structure of a lipoxygenase in complex with substrate: the arachidonic acid-binding site of 8R-lipoxygenase. Neau DB, Bender G, Boeglin WE, Bartlett SG, Brash AR, Newcomer ME (2014) J Biol Chem 289(46): 31905-31913
    › Primary publication · 25231982 (PubMed) · PMC4231669 (PubMed Central)
  6. An ancient relative of cyclooxygenase in cyanobacteria is a linoleate 10S-dioxygenase that works in tandem with a catalase-related protein with specific 10S-hydroperoxide lyase activity. Brash AR, Niraula NP, Boeglin WE, Mashhadi Z (2014) J Biol Chem 289(19): 13101-11
    › Primary publication · 24659780 (PubMed) · PMC4036322 (PubMed Central)
  7. Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis. Thomas CP, Boeglin WE, Garcia-Diaz Y, O'Donnell VB, Brash AR (2013) Chem Phys Lipids : 21-32
    › Primary publication · 23352713 (PubMed) · PMC3678760 (PubMed Central)
  8. Isolation and characterization of two geometric allene oxide isomers synthesized from 9S-hydroperoxylinoleic acid by cytochrome P450 CYP74C3: stereochemical assignment of natural fatty acid allene oxides. Brash AR, Boeglin WE, Stec DF, Voehler M, Schneider C, Cha JK (2013) J Biol Chem 288(29): 20797-20806
    › Primary publication · 23709224 (PubMed) · PMC3774351 (PubMed Central)
  9. Demonstration of HNE-related aldehyde formation via lipoxygenase-catalyzed synthesis of a bis-allylic dihydroperoxide intermediate. Jin J, Zheng Y, Brash AR (2013) Chem Res Toxicol 26(6): 896-903
    › Primary publication · 23668325 (PubMed) · PMC3719183 (PubMed Central)
  10. Biosynthesis, isolation, and NMR analysis of leukotriene A epoxides: substrate chirality as a determinant of the cis or trans epoxide configuration. Jin J, Zheng Y, Boeglin WE, Brash AR (2013) J Lipid Res 54(3): 754-761
    › Primary publication · 23242647 (PubMed) · PMC3617949 (PubMed Central)