Borden Lacy
Last active: 3/24/2020

  1. Identification of a crucial residue required for Staphylococcus aureus LukAB cytotoxicity and receptor recognition. DuMont AL, Yoong P, Liu X, Day CJ, Chumbler NM, James DB, Alonzo F, Bode NJ, Lacy DB, Jennings MP, Torres VJ (2014) Infect Immun 82(3): 1268-76
    › Primary publication · 24379286 (PubMed) · PMC3958006 (PubMed Central)
  2. Structural analysis of the oligomeric states of Helicobacter pylori VacA toxin. Chambers MG, Pyburn TM, González-Rivera C, Collier SE, Eli I, Yip CK, Takizawa Y, Lacy DB, Cover TL, Ohi MD (2013) J Mol Biol 425(3): 524-35
    › Primary publication · 23178866 (PubMed) · PMC3612943 (PubMed Central)
  3. Staphylococcus aureus leukotoxin ED targets the chemokine receptors CXCR1 and CXCR2 to kill leukocytes and promote infection. Reyes-Robles T, Alonzo F, Kozhaya L, Lacy DB, Unutmaz D, Torres VJ (2013) Cell Host Microbe 14(4): 453-9
    › Primary publication · 24139401 (PubMed) · PMC3876884 (PubMed Central)
  4. Molecular assembly of botulinum neurotoxin progenitor complexes. Benefield DA, Dessain SK, Shine N, Ohi MD, Lacy DB (2013) Proc Natl Acad Sci U S A 110(14): 5630-5
    › Primary publication · 23509303 (PubMed) · PMC3619295 (PubMed Central)
  5. Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death. Slater LH, Hett EC, Mark K, Chumbler NM, Patel D, Lacy DB, Collier RJ, Hung DT (2013) ACS Chem Biol 8(4): 812-22
    › Primary publication · 23343607 (PubMed) · PMC3638717 (PubMed Central)
  6. Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex. Farrow MA, Chumbler NM, Lapierre LA, Franklin JL, Rutherford SA, Goldenring JR, Lacy DB (2013) Proc Natl Acad Sci U S A 110(46): 18674-9
    › Primary publication · 24167244 (PubMed) · PMC3831945 (PubMed Central)
  7. Toward a structural understanding of Clostridium difficile toxins A and B. Pruitt RN, Lacy DB (2012) Front Cell Infect Microbiol : 28
    › Primary publication · 22919620 (PubMed) · PMC3417631 (PubMed Central)
  8. Structural determinants of Clostridium difficile toxin A glucosyltransferase activity. Pruitt RN, Chumbler NM, Rutherford SA, Farrow MA, Friedman DB, Spiller B, Lacy DB (2012) J Biol Chem 287(11): 8013-20
    › Primary publication · 22267739 (PubMed) · PMC3318759 (PubMed Central)
  9. Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism. Chumbler NM, Farrow MA, Lapierre LA, Franklin JL, Haslam DB, Haslam D, Goldenring JR, Lacy DB (2012) PLoS Pathog 8(12): e1003072
    › Primary publication · 23236283 (PubMed) · PMC3516567 (PubMed Central)
  10. Studies of the mechanistic details of the pH-dependent association of botulinum neurotoxin with membranes. Mushrush DJ, Koteiche HA, Sammons MA, Link AJ, McHaourab HS, Lacy DB (2011) J Biol Chem 286(30): 27011-8
    › Primary publication · 21652698 (PubMed) · PMC3143659 (PubMed Central)