Borden Lacy
Last active: 3/24/2020

  1. Clostridium sordellii Lethal-Toxin Autoprocessing and Membrane Localization Activities Drive GTPase Glucosylation Profiles in Endothelial Cells. Craven R, Lacy DB (2016) mSphere 1(1)
    › Primary publication · 27303685 (PubMed) · PMC4863631 (PubMed Central)
  2. Clostridium difficile Toxins TcdA and TcdB Cause Colonic Tissue Damage by Distinct Mechanisms. Chumbler NM, Farrow MA, Lapierre LA, Franklin JL, Lacy DB (2016) Infect Immun 84(10): 2871-7
    › Primary publication · 27456833 (PubMed) · PMC5038081 (PubMed Central)
  3. Clostridium difficile Toxin A Undergoes Clathrin-Independent, PACSIN2-Dependent Endocytosis. Chandrasekaran R, Kenworthy AK, Lacy DB (2016) PLoS Pathog 12(12): e1006070
    › Primary publication · 27942025 (PubMed) · PMC5152916 (PubMed Central)
  4. Clostridium difficile infection. Smits WK, Lyras D, Lacy DB, Wilcox MH, Kuijper EJ (2016) Nat Rev Dis Primers : 16020
    › Primary publication · 27158839 (PubMed) · PMC5453186 (PubMed Central)
  5. A Nonoligomerizing Mutant Form of Helicobacter pylori VacA Allows Structural Analysis of the p33 Domain. González-Rivera C, Campbell AM, Rutherford SA, Pyburn TM, Foegeding NJ, Barke TL, Spiller BW, McClain MS, Ohi MD, Lacy DB, Cover TL (2016) Infect Immun 84(9): 2662-70
    › Primary publication · 27382020 (PubMed) · PMC4995914 (PubMed Central)
  6. Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities. Quesada-Gómez C, López-Ureña D, Chumbler N, Kroh HK, Castro-Peña C, Rodríguez C, Orozco-Aguilar J, González-Camacho S, Rucavado A, Guzmán-Verri C, Lawley TD, Lacy DB, Chaves-Olarte E (2016) Infect Immun 84(3): 856-65
    › Primary publication · 26755157 (PubMed) · PMC4771349 (PubMed Central)
  7. The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid. Varela Chavez C, Hoos S, Haustant GM, Chenal A, England P, Blondel A, Pauillac S, Lacy DB, Popoff MR (2015) Cell Microbiol 17(10): 1477-93
    › Primary publication · 25882477 (PubMed)
  8. Identification of an epithelial cell receptor responsible for Clostridium difficile TcdB-induced cytotoxicity. LaFrance ME, Farrow MA, Chandrasekaran R, Sheng J, Rubin DH, Lacy DB (2015) Proc Natl Acad Sci U S A 112(22): 7073-8
    › Primary publication · 26038560 (PubMed) · PMC4460460 (PubMed Central)
  9. Cloning and variation of ground state intestinal stem cells. Wang X, Yamamoto Y, Wilson LH, Zhang T, Howitt BE, Farrow MA, Kern F, Ning G, Hong Y, Khor CC, Chevalier B, Bertrand D, Wu L, Nagarajan N, Sylvester FA, Hyams JS, Devers T, Bronson R, Lacy DB, Ho KY, Crum CP, McKeon F, Xian W (2015) Nature 522(7555): 173-8
    › Primary publication · 26040716 (PubMed) · PMC4853906 (PubMed Central)
  10. Translocation domain mutations affecting cellular toxicity identify the Clostridium difficile toxin B pore. Zhang Z, Park M, Tam J, Auger A, Beilhartz GL, Lacy DB, Melnyk RA (2014) Proc Natl Acad Sci U S A 111(10): 3721-6
    › Primary publication · 24567384 (PubMed) · PMC3956163 (PubMed Central)